1,093 research outputs found

    “You’re On Your Own”: Examining the Wellbeing of Unaccompanied Refugee Minors Who Have Transitioned into Adulthood in the United States

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    The United States\u27 Unaccompanied Refugee Minor (URM) Program, which has served around 13,000 foreign-born children since the 1980s, aims to incorporate unaccompanied refugee minors (URMs) in need of international protection into the child welfare systems of 15 individual states. Despite the fact that children accepted into the URM program have access to the same benefits as those in state custody, URMs face unique challenges from their non-refugee peers. Limited research exists regarding the wellbeing of URMs who have transitioned out of the URM program and into adulthood. This study aimed to explore the experiences of participants who have transitioned out of the URM Program, related to their health (physical/mental), environment, and social connections. Individual in-depth interviews were conducted with 21 adults who have transitioned out of the URM Program across five states. Utilizing the World Health Organization’s Quality of Life Framework (WHO, 2012), the URM program’s “successful integration” outcomes (USCCB, 2013), and domains from the Midwest Evaluation of the Adult Functioning of Former Foster Youth (Midwest study) (Courtney et al., 2007), phenomenological data collection focused on participants’ quality of life, identification of services and supports that have facilitated their transition to adult life, and primary challenges faced. Results showed that despite strong support from URM programs pre-transition, URM youth face significant challenges in adulthood. These challenges include a lack of support post-transition, societal expectations of self-sufficiency, economic insecurity, and difficulty continuing their educational pursuits. Utilizing the findings from this study, policy and practice recommendations are proposed to help inform future service provision for URMs transitioning out of the URM program. Recommendations are also made for future research on this population, based on the study’s findings

    From stem and progenitor cells to neurons in the developing neocortex: Key differences among hominids

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    Comparing the biology of humans to that of other primates, and notably other hominids, is a useful path to learn more about what makes us human. Some of the most interesting differences among hominids are closely related to brain development and function, for example behaviour and cognition. This makes it particularly interesting to compare the hominid neural cells of the neocortex, a part of the brain that plays central roles in those processes. However, well-preserved tissue from great apes is usually extremely difficult to obtain. A variety of new alternative tools, for example brain organoids, are now beginning to make it possible to search for such differences and analyse their potential biological and biomedical meaning. Here, we present an overview of recent findings from comparisons of the neural stem and progenitor cells (NSPCs) and neurons of hominids. In addition to differences in proliferation and differentiation of NSPCs, and maturation of neurons, we highlight that the regulation of the timing of these processes is emerging as a general foundational difference in the development of the neocortex of hominids

    The influence of Hickson-like compact group environment on galaxy luminosities

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    Compact groups of galaxies are devised as extreme environments where interactions may drive galaxy evolution. In this work, we analysed whether the luminosities of galaxies inhabiting compact groups differ from those of galaxies in loose galaxy groups. We computed the luminosity functions of galaxy populations inhabiting a new sample of 1412 Hickson-like compact groups of galaxies identified in the Sloan Digital Sky Survey Data Release 16. We observed a characteristic absolute magnitude for galaxies in compact groups brighter than that observed in the field or loose galaxy systems. We also observed a deficiency of faint galaxies in compact groups in comparison with loose systems. Our analysis showed that the brightening is mainly due to galaxies inhabiting the more massive compact groups. In contrast to what is observed in loose systems, where only the luminosities of Red (and Early) galaxies show a dependency with group mass, luminosities of Red and Blue (also Early and Late) galaxies in compact groups are affected similarly as a function of group virial mass. When using Hubble types, we observed that elliptical galaxies in compact groups are the brightest galaxy population, and groups dominated by an elliptical galaxy also display the brightest luminosities in comparison with those dominated by spiral galaxies. Moreover, we show that the general luminosity trends can be reproduced using a mock catalogue obtained from a semi-analytical model of galaxy formation. These results suggest that the inner extreme environment in compact groups prompts a different evolutionary history for their galaxies.Fil: Zandivarez, Arnaldo Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba; ArgentinaFil: Díaz Giménez, E.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba; ArgentinaFil: Taverna, Maria Antonela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Astronomía Teórica y Experimental. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba. Instituto de Astronomía Teórica y Experimental; Argentina. Universidad Nacional de Córdoba. Observatorio Astronómico de Córdoba; Argentin

    Aplicação de métodos quimiométricos em análises não-destrutivas de Eucalyptus grandis.

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    Este trabalho teve como objetivo a construção de uma curva de calibração utilizando a espectroscopia no infravermelho próximo (NIR) para predição de propriedades físicas como densidade básica, retratibilidade radial, longitudinal e tangencial e anisotropia de contração de amostras de Eucalyptus grandis. A partir de análise matemática multivariada dos resultados observou-se que existe correlação estatística, de acordo com o modelo proposto, com as propriedades retratibilidade radial e longitudinal

    miR-214 coordinates melanoma progression by upregulating ALCAM through TFAP2 and miR-148b downmodulation.

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    Malignant melanoma is one of the most aggressive human cancers, but the mechanisms governing its metastatic dissemination are not fully understood. Upregulation of miR-214 and ALCAM and the loss of TFAP2 expression have been implicated in this process, with TFAP2 a direct target of miR-214. Here, we link miR-214 and ALCAM as well as identify a core role for miR-214 in organizing melanoma metastasis. miR- 214 upregulated ALCAM, acting transcriptionally through TFAP2 and also posttranscriptionally through miR-148b (itself controlled by TFAP2), both negative regulators of ALCAM. We also identified several miR-214–mediated prometastatic functions directly promoted by ALCAM. Silencing ALCAM in miR-214–overexpressing melanoma cells reduced cell migration and invasion without affecting growth or anoikisin vitro, and it also impaired extravasation and metastasis formation in vivo. Conversely, cell migration and extravasation was reduced in miR-214–overexpressing cells by upregulation of either miR 148b or TFAP2. These findings were consistent with patterns of expression of miR-214, ALCAM, and miR-148b in human melanoma specimens. Overall, our results define a pathway involving miR-214, miR-148b, TFAP2, and ALCAM that is critical for establishing distant metastases in melanoma

    Compact groups from semi-analytical models of galaxy formation -- V: their assembly channels as a function of the environment

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    We delved into the assembly pathways and environments of compact groups (CGs) of galaxies using mock catalogues generated from semi-analytical models (SAMs) on the Millennium simulation. We investigate the ability of SAMs to replicate the observed CG environments and whether CGs with different assembly histories tend to inhabit specific cosmic environments. We also analyse whether the environment or the assembly history is more important in tailoring CG properties. We find that about half of the CGs in SAMs are non-embedded systems, 40% are inhabiting loose groups or nodes of filaments, while the rest distribute evenly in filaments and voids, in agreement with observations. We observe that early-assembled CGs preferentially inhabit large galaxy systems (~ 60%), while around 30% remain non-embedded. Conversely, lately-formed CGs exhibit the opposite trend. We also obtain that lately-formed CGs have lower velocity dispersions and larger crossing times than early-formed CGs, but mainly because they are preferentially non-embedded. Those lately-formed CGs that inhabit large systems do not show the same features. Therefore, the environment plays a strong role in these properties for lately-formed CGs. Early-formed CGs are more evolved, displaying larger velocity dispersions, shorter crossing times, and more dominant first-ranked galaxies, regardless of the environment. Finally, the difference in brightness between the two brightest members of CGs is dependent only on the assembly history and not on the environment. CGs residing in diverse environments have undergone varied assembly processes, making them suitable for studying their evolution and the interplay of nature and nurture on their traits.Comment: 13 pages, 8 figures. Accepted for publication in MNRA

    Fractional Brownian motions ruled by nonlinear equations

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    In this note we consider generalized diffusion equations in which the diffusivity coefficient is not necessarily constant in time, but instead it solves a nonlinear fractional differential equation involving fractional Riemann–Liouville time-derivative. Our main contribution is to highlight the link between these generalised equations and fractional Brownian motion (fBm). In particular, we investigate the governing equation of fBm and show that its diffusion coefficient must satisfy an additive evolutive fractional equation. We derive in a similar way the governing equation of the iterated fractional Brownian motion
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