De-biasing interferometric visibilities in VLTI-AMBER data of low SNR observations

AIMS: We have found that the interferometric visibilities of VLTI-AMBER observations, extracted via the standard reduction package, are significantly biased when faint targets are concerned. The visibility biases derive from a time variable fringing effect (correlated noise) appearing on the detector. METHODS: We have developed a method to correct this bias that consists in a subtraction of the extra power due to such correlated noise, so that the real power spectrum at the spatial frequencies of the fringing artifact can be restored. RESULTS: This pre-processing procedure is implemented in a software, called AMDC and available to the community, to be run before the standard reduction package. Results obtained on simulated and real observations are presented and discussed.Comment: 7 pages, 9 figure

AMBER on the VLTI: data processing and calibration issues

We present here the current performances of the AMBER / VLTI instrument for standard use and compare these with the offered modes of the instrument. We show that the instrument is able to reach its specified precision only for medium and high spectral resolution modes, differential observables and bright objects. For absolute observables, the current achievable accuracy is strongly limited by the vibrations of the Unit Telescopes, and also by the observing procedure which does not take into account the night-long transfer function monitoring. For low-resolution mode, the current limitation is more in the data reduction side, since several effects negligible at medium spectral resolution are not taken into account in the current pipeline. Finally, for faint objects (SNR around 1 per spectral channel), electromagnetic interferences in the VLTI interferometric laboratory with the detector electronics prevents currently to get unbiased measurements. Ideas are under study to correct in the data processing side this effect, but a hardware fix should be investigated seriously since it limits seriously the effective limiting magnitude of the instrument.Comment: 10 page

Mitochondrial Hormesis links nutrient restriction to improved metabolism in fat cell

Fasting promotes longevity by reprogramming metabolic and stress resistance pathways. However, although the impact on adipose tissue physiology through hormonal inputs is well established, the direct role of fasting on adipose cells is poorly understood. Herein we show that white and beige adipocytes, as well as mouse epididymal and subcutaneous adipose depots, respond to nutrient scarcity by acquiring a brown-like phenotype. Indeed, they improve oxidative metabolism through modulating the expression of mitochondrial- and nuclear-encoded oxidative phosphorylation genes as well as mitochondrial stress defensive proteins (UCP1, SOD2). Such adaptation is placed in a canonical mitohormetic response that proceeds via mitochondrial reactive oxygen species ((mt)ROS) production and redistribution of FoxO1 transcription factor into nucleus. Nuclear FoxO1 ((n)FoxO1) mediates retrograde communication by inducing the expression of mitochondrial oxidative and stress defensive genes. Collectively, our findings describe an unusual white/beige fat cell response to nutrient availability highlighting another health-promoting mechanism of fasting

First astrophysical results from AMBER/VLTI

The AMBER instrument installed at the Very Large Telescope (VLT) combines three beams from as many telescopes to produce spectrally dispersed fringes from milli-arcsecond angular scale in the near infrared. Two years after installation, first scientific observations have been carried out during the Science Demonstration Time and the Guaranteed Time mostly on bright sources due to some VLTI limitations. In this paper, we review these first astrophysical results and we show which types of completely new information is brought by AMBER. The first astrophysical results have been mainly focusing on stellar wind structure, kinematics, and its interaction with dust usually concentrated in a disk. Because AMBER has dramatically increased the number of measures per baseline, this instrument brings strong constraints on morphology and models despite a relatively poor (u, v) coverage for each object.Comment: SPIE 6268 proceeding

Near-infrared interferometric observation of the Herbig Ae star HD144432 with VLTI/AMBER

We study the sub-AU-scale circumstellar environment of the Herbig Ae star HD144432 with near-infrared (NIR) VLTI/AMBER observations to investigate the structure of its inner dust disk. The interferometric observations were carried out with the AMBER instrument in the H and K band. We interpret the measured H- and K-band visibilities, the near- and mid-infrared visibilities from the literature, and the SED of HD144432 by using geometric ring models and ring-shaped temperature-gradient disk models with power-law temperature distributions. We derived a K-band ring-fit radius of 0.17 \pm 0.01 AU and an H-band radius of 0.18 \pm 0.01 AU (for a distance of 145 pc). This measured K-band radius of \sim0.17 AU lies in the range between the dust sublimation radius of \sim0.13 AU (predicted for a dust sublimation temperature of 1500 K and gray dust) and the prediction of models including backwarming (\sim0.27 AU). We found that an additional extended halo component is required in both the geometric and temperature-gradient modeling. In the best temperature- gradient model, the disk consists of two components. The inner part of the disk is a thin ring with an inner radius of \sim0.21 AU, a temperature of \sim1600 K, and a ring thickness \sim0.02 AU. The outer part extends from \sim1 AU to \sim10 AU with an inner temperature of \sim400 K. We find that the disk is nearly face-on with an inclination angle of < 28 degree. Our temperature-gradient modeling suggests that the NIR excess is dominated by emission from a narrow, bright rim located at the dust sublimation radius, while an extended halo component contributes \sim6% to the total flux at 2 {\mu}m. The MIR model emission has a two-component structure with \sim20% flux from the inner ring and the rest from the outer part. This two-component structure suggests a disk gap, which is possibly caused by the shadow of a puffed-up inner rim.Comment: 7 pages, 5 figures, accepted by A&

Data reduction for the AMBER instrument

We present here the general formalism and data processing steps used in the data reduction pipeline of the AMBER instrument. AMBER is a three-telescope interferometric beam combiner in J, H and K bands installed at ESO\'s Very Large Telescope Interferometer. The fringes obtained on the 3 pairs of telescopes are spatially coded and spectrally dispersed. These are monitored on a 512x512 infrared camera at frame rates up to 100 frames per second, and this paper presents the algorithm used to retrieve the complex coherent visibility of the science target and the subsequent squared visibility, dierential phase and phase closure on the 3 bases and in the 3 spectral bands available in AMBER

Glutathione Decrement Drives Thermogenic Program in Adipose Cells

Adipose tissue metabolically adapts to external stimuli. We demonstrate that the induction of the thermogenic program in white adipocytes, through cold exposure in mice or in vitro adrenergic stimulation, is accompanied by a decrease in the intracellular content of glutathione (GSH). Moreover, the treatment with a GSH depleting agent, buthionine sulfoximine (BSO), recapitulates the effect of cold exposure resulting in the induction of thermogenic program. In particular, BSO treatment leads to enhanced uncoupling respiration as demonstrated by increased expression of thermogenic genes (e.g. Ucp1, Ppargc1a), augmented oxygen consumption and decreased mitochondrial transmembrane potential. Buffering GSH decrement by pre-treatment with GSH ester prevents the up-regulation of typical markers of uncoupling respiration. We demonstrate that FoxO1 activation is responsible for the conversion of white adipocytes into a brown phenotype as the "browning" effects of BSO are completely abrogated in cells down-regulating FoxO1. In mice, the BSO-mediated up-regulation of uncoupling genes results in weight loss that is at least in part ascribed to adipose tissue mass reduction. The induction of thermogenic program has been largely proposed to counteract obesity-related diseases. Based on these findings, we propose GSH as a novel therapeutic target to increase energy expenditure in adipocytes.Adipose tissue metabolically adapts to external stimuli. We demonstrate that the induction of the thermogenic program in white adipocytes, through cold exposure in mice or in vitro adrenergic stimulation, is accompanied by a decrease in the intracellular content of glutathione (GSH). Moreover, the treatment with a GSH depleting agent, buthionine sulfoximine (BSO), recapitulates the effect of cold exposure resulting in the induction of thermogenic program. In particular, BSO treatment leads to enhanced uncoupling respiration as demonstrated by increased expression of thermogenic genes (e.g. Ucp1, Ppargc1a), augmented oxygen consumption and decreased mitochondrial transmembrane potential. Buffering GSH decrement by pre-treatment with GSH ester prevents the up-regulation of typical markers of uncoupling respiration. We demonstrate that FoxO1 activation is responsible for the conversion of white adipocytes into a brown phenotype as the "browning" effects of BSO are completely abrogated in cells down-regulating FoxO1. In mice, the BSO-mediated up-regulation of uncoupling genes results in weight loss that is at least in part ascribed to adipose tissue mass reduction. The induction of thermogenic program has been largely proposed to counteract obesity-related diseases. Based on these findings, we propose GSH as a novel therapeutic target to increase energy expenditure in adipocytes

The 2008 outburst in the young stellar system ZCMa: I. Evidence of an enhanced bipolar wind on the AU-scale

Accretion is a fundamental process in star formation. Although the time evolution of accretion remains a matter of debate, observations and modelling studies suggest that episodic outbursts of strong accretion may dominate the formation of the protostar. Observing young stellar objects during these elevated accretion states is crucial to understanding the origin of unsteady accretion. ZCMa is a pre-main-sequence binary system composed of an embedded Herbig Be star, undergoing photometric outbursts, and a FU Orionis star. The Herbig Be component recently underwent its largest optical photometric outburst detected so far. We aim to constrain the origin of this outburst by studying the emission region of the HI Brackett gamma line, a powerful tracer of accretion/ejection processes on the AU-scale in young stars. Using the AMBER/VLTI instrument at spectral resolutions of 1500 and 12 000, we performed spatially and spectrally resolved interferometric observations of the hot gas emitting across the Brackett gamma emission line, during and after the outburst. From the visibilities and differential phases, we derive characteristic sizes for the Brackett gamma emission and spectro-astrometric measurements across the line, with respect to the continuum. We find that the line profile, the astrometric signal, and the visibilities are inconsistent with the signature of either a Keplerian disk or infall of matter. They are, instead, evidence of a bipolar wind, maybe partly seen through a disk hole inside the dust sublimation radius. The disappearance of the Brackett gamma emission line after the outburst suggests that the outburst is related to a period of strong mass loss rather than a change of the extinction along the line of sight. Based on these conclusions, we speculate that the origin of the outburst is an event of enhanced mass accretion, similar to those occuring in EX Ors and FU Ors.Comment: Accepted for publication in Astronomy and Astrophysics Letter

Ellipsoidal primary of the RS CVn binary zeta And: Investigation using high-resolution spectroscopy and optical interferometry

We have obtained high-resolution spectroscopy, optical interferometry, and long-term broad band photometry of the ellipsoidal primary of the RS CVn-type binary system zeta And. Based on the optical interferometry the apparent limb darkened diameter of zeta And is 2.55 +/- 0.09 mas using a uniform disk fit. The Hipparcos distance and the limb-darkened diameter obtained with a uniform disk fit give stellar radius of 15.9 +/- 0.8 Rsolar, and combined with bolometric luminosity, it implies an effective temperature of 4665 +/- 140 K. The temperature maps obtained from high resolution spectra using Doppler imaging show a strong belt of equatorial spots and hints of a cool polar cap. The equatorial spots show a concentration around the phase 0.75. This spot configuration is reminiscent of the one seen in the earlier published temperature maps of zeta And. Investigation of the Halpha line reveals both prominences and cool clouds in the chromosphere. Long-term photometry spanning 12 years shows hints of a spot activity cycle, which is also implied by the Doppler images, but the cycle length cannot be reliably determined from the current data.Comment: 9 pages, 9 figures, accepted for A&

The origin of hydrogen line emission for five Herbig Ae/Be stars spatially resolved by VLTI/AMBER spectro-interferometry

To trace the accretion and outflow processes around YSOs, diagnostic spectral lines such as the BrG 2.166 micron line are widely used, although due to a lack of spatial resolution, the origin of the line emission is still unclear. Employing the AU-scale spatial resolution which can be achieved with infrared long-baseline interferometry, we aim to distinguish between theoretical models which associate the BrG line emission with mass infall or mass outflow processes. Using the VLTI/AMBER instrument, we spatially and spectrally (R=1500) resolved the inner environment of five Herbig Ae/Be stars (HD163296, HD104237, HD98922, MWC297, V921Sco) in the BrG emission line as well as in the adjacent continuum. All objects (except MWC297) show an increase of visibility within the BrG emission line, indicating that the BrG-emitting region in these objects is more compact than the dust sublimation radius. For HD98922, our quantitative analysis reveals that the line-emitting region is compact enough to be consistent with the magnetospheric accretion scenario. For HD163296, HD104237, MWC297, and V921Sco we identify a stellar wind or a disk wind as the most likely line-emitting mechanism. We search for general trends and find that the size of the BrG-emitting region does not seem to depend on the basic stellar parameters, but correlates with the H-alpha line profile shape. We find evidence for at least two distinct BrG line-formation mechanisms. Stars with a P-Cygni H-alpha line profile and a high mass-accretion rate seem to show particularly compact BrG-emitting regions (R_BrG/R_cont<0.2), while stars with a double-peaked or single-peaked H-alpha-line profile show a significantly more extended BrG-emitting region (0.6<R_BrG/R_cont<1.4), possibly tracing a stellar wind or a disk wind.Comment: 20 pages; 11 figures; Accepted by A&A; a high quality version of the paper can be obtained at http://www.skraus.eu/papers/kraus.HAeBe-BrGsurvey.pd