Observations of Detailed Structure in the Solar Wind at 1 AU with STEREO/HI-2

Heliospheric imagers offer the promise of remote sensing of large-scale structures present in the solar wind. The STEREO/HI-2 imagers, in particular, offer high resolution, very low noise observations of the inner heliosphere but have not yet been exploited to their full potential. This is in part because the signal of interest, Thomson scattered sunlight from free electrons, is ~1000 times fainter than the background visual field in the images, making background subtraction challenging. We have developed a procedure for separating the Thomson-scattered signal from the other background/foreground sources in the HI-2 data. Using only the Level 1 data from STEREO/HI-2, we are able to generate calibrated imaging data of the solar wind with sensitivity of a few times 1e-17 Bsun, compared to the background signal of a few times 1e-13 Bsun. These images reveal detailed spatial structure in CMEs and the solar wind at projected solar distances in excess of 1 AU, at the instrumental motion-blur resolution limit of 1-3 degree. CME features visible in the newly reprocessed data from December 2008 include leading-edge pileup, interior voids, filamentary structure, and rear cusps. "Quiet" solar wind features include V shaped structure centered on the heliospheric current sheet, plasmoids, and "puffs" that correspond to the density fluctuations observed in-situ. We compare many of these structures with in-situ features detected near 1 AU. The reprocessed data demonstrate that it is possible to perform detailed structural analyses of heliospheric features with visible light imagery, at distances from the Sun of at least 1 AU.Comment: Accepted by Astrophysical Journa

Major epidemiological changes in sudden infant death syndrome : a 20-year population-based study in the UK

Background Results of case-control studies in the past 5 years suggest that the epidemiology of sudden infant death syndrome (SIDS) has changed since the 1991 UK Back to Sleep campaign. The campaign's advice that parents put babies on their back to sleep led to a fall in death rates. We used a longitudinal dataset to assess these potential changes. Methods Population-based data from home visits have been collected for 369 consecutive unexpected infant deaths (300 SIDS and 69 explained deaths) in Avon over 20 years (1984—2003). Data obtained between 1993 and 1996 from 1300 controls with a chosen “reference” sleep before interview have been used for comparison. Findings Over the past 20 years, the proportion of children who died from SIDS while co-sleeping with their parents, has risen from 12% to 50% (p<0·0001), but the actual number of SIDS deaths in the parental bed has halved (p=0·01). The proportion seems to have increased partly because the Back to Sleep campaign led to fewer deaths in infants sleeping alone—rather than because of a rise in deaths of infants who bed-shared, and partly because of an increase in the number of deaths in infants sleeping with their parents on a sofa. The proportion of deaths in families from deprived socioeconomic backgrounds has risen from 47% to 74% (p=0·003), the prevalence of maternal smoking during pregnancy from 57% to 86% (p=0·0004), and the proportion of pre-term infants from 12% to 34% (p=0·0001). Although many SIDS infants come from large families, first-born infants are now the largest group. The age of infants who bed-share is significantly smaller than that before the campaign, and fewer are breastfed. Interpretation Factors that contribute to SIDS have changed in their importance over the past 20 years. Although the reasons for the rise in deaths when a parent sleeps with their infant on a sofa are still unclear, we strongly recommend that parents avoid this sleeping environment. Most SIDS deaths now occur in deprived families. To better understand contributory factors and plan preventive measures we need control data from similarly deprived families, and particularly, infant sleep environments

Pharmaceuticals in soils of lower income countries: Physico-chemical fate and risks from wastewater irrigation.

Population growth, increasing affluence, and greater access to medicines have led to an increase in active pharmaceutical ingredients (APIs) entering sewerage networks. In areas with high wastewater reuse, residual quantities of APIs may enter soils via irrigation with treated, partially treated, or untreated wastewater and sludge. Wastewater used for irrigation is currently not included in chemical environmental risk assessments and requires further consideration in areas with high water reuse. This study critically assesses the contemporary understanding of the occurrence and fate of APIs in soils of low and lower-middle income countries (LLMIC) in order to contribute to the development of risk assessments for APIs in LLMIC. The physico-chemical properties of APIs and soils vary greatly globally, impacting on API fate, bioaccumulation and toxicity. The impact of pH, clay and organic matter on the fate of organic ionisable compounds is discussed in detail. This study highlights the occurrence and the partitioning and degradation coefficients for APIs in soil:porewater systems, API usage data in LLMICS and removal rates (where used) within sewage treatment plants as key areas where data are required in order to inform robust environmental risk assessment methodologies

Source of the tsunami generated by the 1650 AD eruption of Kolumbo submarine volcano (Aegean Sea, Greece)

The 1650 AD explosive eruption of Kolumbo submarine volcano (Aegean Sea, Greece) generated a destructive tsunami. In this paper we propose a source mechanism of this poorly documented tsunami using both geological investigations and numerical simulations. Sedimentary evidence of the 1650 AD tsunami was found along the coast of Santorini Island at maximum altitudes ranging between 3.5 m a.s.l. (Perissa, southern coast) and 20 m a.s.l. (Monolithos, eastern coast), corresponding to a minimum inundation of 360 and 630 m respectively. Tsunami deposits consist of an irregular 5 to 30 cm thick layer of dark grey sand that overlies pumiceous deposits erupted during the Minoan eruption and are found at depths of 30–50 cm below the surface. Composition of the tsunami sand is similar to the composition of the present-day beach sand but differs from the pumiceous gravelly deposits on which it rests. The spatial distribution of the tsunami deposits was compared to available historical records and to the results of numerical simulations of tsunami inundation. Different source mechanisms were tested: earthquakes, underwater explosions, caldera collapse, and pyroclastic flows. The most probable source of the 1650 AD Kolumbo tsunami is a 250 m high water surface displacement generated by underwater explosion with an energy of ~ 2 × 1016 J at water depths between 20 and 150 m. The tsunamigenic explosion(s) occurred on September 29, 1650 during the transition between submarine and subaerial phases of the eruption. Caldera subsidence is not an efficient tsunami source mechanism as short (and probably unrealistic) collapse durations (< 5 min) are needed. Pyroclastic flows cannot be discarded, but the required flux (106 to 107 m3 · s− 1) is exceptionally high compared to the magnitude of the eruption

The cessation in pregnancy incentives trial (CPIT): study protocol for a randomized controlled trial

Background: Seventy percent of women in Scotland have at least one baby, making pregnancy an opportunity to help most young women quit smoking before their own health is irreparably compromised. By quitting during pregnancy their infants will be protected from miscarriage and still birth as well as low birth weight, asthma, attention deficit disorder and adult cardiovascular disease. In the UK, the NICE guidelines: 'How to stop smoking in pregnancy and following childbirth' (June 2010) highlighted that little evidence exists in the literature to confirm the efficacy of financial incentives to help pregnant smokers to quit. Its first research recommendation was to determine: Within a UK context, are incentives an acceptable, effective and cost-effective way to help pregnant women who smoke to quit? &lt;p/&gt;Design and Methods: This study is a phase II exploratory individually randomised controlled trial comparing standard care for pregnant smokers with standard care plus the additional offer of financial voucher incentives to engage with specialist cessation services and/or to quit smoking during pregnancy. Participants (n=600) will be pregnant smokers identified at maternity booking who when contacted by specialist cessation services agree to having their details passed to the NHS Smokefree Pregnancy Study Helpline to discuss the trial. The NHS Smokefree Pregnancy Study Helpline will be responsible for telephone consent and follow-up in late pregnancy. The primary outcome will be self reported smoking in late pregnancy verified by cotinine measurement. An economic evaluation will refine cost data collection and assess potential cost-effectiveness while qualitative research interviews with clients and health professionals will assess the level of acceptance of this form of incentive payment. Research questions What is the likely therapeutic efficacy? Are incentives potentially cost-effective? Is individual randomisation an efficient trial design without introducing outcome bias? Can incentives be introduced in a way that is feasible and acceptable? &lt;p/&gt;Discussion: This phase II trial will establish a workable design to reduce the risks associated with a future definitive phase III multicentre randomised controlled trial and establish a framework to assess the costs and benefits of financial incentives to help pregnant smokers to quit

Duration of breastfeeding and risk of SIDS: an individual participant data meta-analysis

CONTEXT: Sudden infant death syndrome (SIDS) is a leading cause of postneonatal infant mortality. Our previous meta-analyses showed that any breastfeeding is protective against SIDS with exclusive breastfeeding conferring a stronger effect.The duration of breastfeeding required to confer a protective effect is unknown. OBJECTIVE: To assess the associations between breastfeeding duration and SIDS. DATA SOURCES: Individual-level data from 8 case-control studies. STUDY SELECTION: Case-control SIDS studies with breastfeeding data. DATA EXTRACTION: Breastfeeding variables, demographic factors, and other potential confounders were identified. Individual-study and pooled analyses were performed. RESULTS: A total of 2267 SIDS cases and 6837 control infants were included. In multivariable pooled analysis, breastfeeding for &#60;2 months was not protective (adjusted odds ratio [aOR]: 0.91, 95% confidence interval [CI]: 0.68–1.22). Any breastfeeding ≥2 months was protective, with greater protection seen with increased duration (2–4 months: aOR: 0.60, 95% CI: 0.44–0.82; 4–6 months: aOR: 0.40, 95% CI: 0.26–0.63; and &gt;6 months: aOR: 0.36, 95% CI: 0.22–0.61). Although exclusive breastfeeding for &#60;2 months was not protective (aOR: 0.82, 95% CI: 0.59–1.14), longer periods were protective (2–4 months: aOR: 0.61, 95% CI: 0.42–0.87; 4–6 months: aOR: 0.46, 95% CI: 0.29–0.74). LIMITATIONS: The variables collected in each study varied slightly, limiting our ability to include all studies in the analysis and control for all confounders. CONCLUSIONS: Breastfeeding duration of at least 2 months was associated with half the risk of SIDS. Breastfeeding does not need to be exclusive to confer this protection