760 research outputs found
Quantitative assessment of reflex blood pressure regulation using a dynamic model of the cardiovascular system
A quantitative understanding of the changes in coronary, pulmonary and systemic hemodynamic variables and their effects on the regulation mechanism is important to the better postoperative management of patients with impaired cardiac function. The arterial baroreflex plays a key role in blood pressure homeostasis, and its impairment may result in exaggerated blood pressure fluctuations and an increased risk of cardiovascular morbid events.
The objective of this work was to construct a mathematical model of the cardiovascular system, which will allow us to simulate the effects of the baroreceptor reflex regulation on sudden changes in blood pressure, caused by sudden changes in one or more hemodynamic parameters. These parameters include heart rate, peripheral resistance and ventricular contractility. A comprehensive model of the baroreflexfeedback mechanism regulating the heart rate, the contractility of the ventricle and the peripheral vascular resistance is presented. The model used is a combination of several models, which have been reported in literature, along with our own modifications. The important feature of the model is that it is dynamic in nature and thus it is helpful in real time analysis. The model is also useful to conceptualize the problem and test relationships, helping researchers frame hypotheses and design experiments
Social movement against corruption: Evaluating the contribution of Transparency International Bangladesh (TIB)
Addressing corruption requires active public participation. Transparency International Bangladesh (TIB) strives to mobilize Bangladeshi citizens in an anti-corruption social movement. This research explores TIB’s activities (research, communication and engagement) and investigates their achievements. The study finds that besides building capacity among stakeholders, TIB creates a unique trustworthy brand among people. Potential issues triggered by over-expectation, discontinuity and expanding the scope of work are identified and recommendations are made to facilitate TIB’s resilience and efficiency
Comparison of 99mTc-DMSA renal scintigraphy with biochemical and histopathological findings in animal models of acute kidney injury
Biochemical and histological assays are currently
used for the diagnosis and characterization of kidney
injury. The purpose of this study was to compare technetium-
99m-labeled dimercaptosuccinic acid (99mTc-
DMSA) renal scintigraphy, as a non-invasive method, with
common biochemical and histopathological methods in
two animal models of acute kidney injury. Nephrotoxicity
was induced either by gentamicin (100 mg/kg/day for one
week) or unilateral ureteral ligation (UUO). Renal
scintigraphy was performed 1 h after intravenous injection
of 99mTc-DMSA (3 mCi). Furthermore, plasma levels of
blood urea nitrogen (BUN), creatinine, sodium, and
potassium were determined using an autoanalyzer. At the
end of experiments, kidneys were excised for the measurement
of activity uptake (mCi/gr) using a dose calibrator
as well as histopathological examinations with
hematoxylin and eosin (H&E) staining. There was a significant
decrease in 99mTc-DMSA uptake in both gentamicin
(P value = 0.049) and UUO (P value = 0.034)
groups, and it was more significant in the former. The
levels of BUN and creatinine increased in both gentamicin
and UUO groups, while the levels of sodium and potassium
remained unchanged. Furthermore, a strong correlation was
found between DMSA uptake and histopathological findings.
Scintigraphy with 99mTc-DMSA is capable of
detection of kidney injury in both gentamicin and UUO
groups. Moreover, a significant correlation was found
between scintigraphy parameters and histopathological
findings. This suggests 99mTc-DMSA as a non-invasive
method for the evaluation of kidney injury induced by
drugs or anatomical disorders
Reply to Comments on "Overlapped Phased Array Antenna for Avalanche Radar"
In this reply, we refer to comments made by a
reader on our publication “Overlapped Phased Array Antenna
for Avalanche Radar”. Authors would like to thank the reader
for reading the paper. In this paper authors provided detailed
answers to the comments made by the reade
Oil Price Shocks and Renewable Energy Transition: Empirical evidence from net oil-importing South Asian economies
This paper makes a novel attempt to model the non-linear association between renewable energy consumption and crude oil prices across four net oil-importing South Asian economies namely Bangladesh, India, Pakistan and Sri Lanka. Using annual data from 1990 to 2018, the results from the panel data regression analyses confirm the non-linear nexus and show that although rising crude oil prices do not facilitate renewable energy consumption initially, in the latter phases higher crude oil prices are associated with higher levels of renewable energy consumption. The similar non-linearity is also confirmed in the context of the renewable energy share in total final energy consumption and crude oil prices. Moreover, the nexus between renewable electricity share in aggregate electricity output and crude oil prices is also found to be non-linear in nature. However, rising crude oil prices were not found to enhance the share of renewable electricity. The causality results, overall, implicates that movements crude oil prices do influence the renewable energy transition within the concerned South Asian economies. Thus, these results impose critically important policy implications with respect to attainment of energy security and environmental sustainability across South Asia, particularly via reducing the imported crude oil-dependencies of these nations
“Exploring leadership behavior in support of gender diversity as a competitive advantage: A case study on Nordic service industry”.
This dissertation explores the leadership behavior and perspective through leadership
ontologies that support gender diversity to gain competitive advantage. The present and past
literature on diversity leadership is focused more on identifying to “fix” diversity with the
end goal of improving the KPI of the organization. Only a few studies have demonstrated the
leadership behaviors to embrace diversity as a strength, a source of value, and a competitive
advantage. Therefore, this research aims to fill this gap in the literature, as it focuses on the
leadership perceptions to get meaningful progress in the corporate gender diversity programs.
The research questions then become:
Which leadership behaviors support gender diversity to achieve competitive advantage?
A study aimed to answer this question and look at all three leadership ontologies: tripod
ontology, DAC, and PAC, and how they would function in the Nordic hotel and IT service
sectors. Empirical data was collected through interviews of employees in the formal and
informal leadership positions in 2 hotels and 1 IT company.
This dissertation has the world view of interpretivism, and the analysis is qualitative content
analysis. And the data reveals that there are six main themes of relevance to the problem
question. The findings suggest that tripod ontology, where leadership influences most of its
integration and expects followers and shared goals to follow, has adverse effects on gender
diversity in the hotel and IT industry. DAC ontology which focuses on collective interest,
coordination of knowledge and works and has a widespread agreement on the overall goals,
mission, and vision, has limited practice. Still, it can diversely affect the integration of gender
diversity in both industries. PAC ontology which defines leadership as a collective pursuit of
delivering on purpose, not a privilege of the few, has a mixed findings in this research. In the
hotel sector, leaders tried to implement gender equality within their organization in a way that
hasn’t had known to have a business value, on the other hand, the IT sector has an excellent
potential to implement PAC to integrate gender.
This dissertation is based on a paradigm that allows for consistent re-evaluation of the
problem question. However, the main recommendation is to develop the problem question
early and review the literature at a stage where one can utilize the literature to form a problem
question. In addition, this dissertation recommends the careful use of leadership definitions.
Because there are so much disagreement and vagueness among scholars in this field, this thesis also suggests combining leadership studies with quantifiable data besides qualitative
data
Exploring leadership behavior in support of gender diversity as a competitive advantage: A case study on Nordic service industry
This dissertation explores the leadership behavior and perspective through leadership
ontologies that support gender diversity to gain competitive advantage. The present and past
literature on diversity leadership is focused more on identifying to “fix” diversity with the
end goal of improving the KPI of the organization. Only a few studies have demonstrated the
leadership behaviors to embrace diversity as a strength, a source of value, and a competitive
advantage. Therefore, this research aims to fill this gap in the literature, as it focuses on the
leadership perceptions to get meaningful progress in the corporate gender diversity programs.
The research questions then become:
Which leadership behaviors support gender diversity to achieve competitive advantage?
A study aimed to answer this question and look at all three leadership ontologies: tripod
ontology, DAC, and PAC, and how they would function in the Nordic hotel and IT service
sectors. Empirical data was collected through interviews of employees in the formal and
informal leadership positions in 2 hotels and 1 IT company.
This dissertation has the world view of interpretivism, and the analysis is qualitative content
analysis. And the data reveals that there are six main themes of relevance to the problem
question. The findings suggest that tripod ontology, where leadership influences most of its
integration and expects followers and shared goals to follow, has adverse effects on gender
diversity in the hotel and IT industry. DAC ontology which focuses on collective interest,
coordination of knowledge and works and has a widespread agreement on the overall goals,
mission, and vision, has limited practice. Still, it can diversely affect the integration of gender
diversity in both industries. PAC ontology which defines leadership as a collective pursuit of
delivering on purpose, not a privilege of the few, has a mixed findings in this research. In the
hotel sector, leaders tried to implement gender equality within their organization in a way that
hasn’t had known to have a business value, on the other hand, the IT sector has an excellent
potential to implement PAC to integrate gender.
This dissertation is based on a paradigm that allows for consistent re-evaluation of the
problem question. However, the main recommendation is to develop the problem question
early and review the literature at a stage where one can utilize the literature to form a problem
question. In addition, this dissertation recommends the careful use of leadership definitions.
Because there are so much disagreement and vagueness among scholars in this field, this thesis also suggests combining leadership studies with quantifiable data besides qualitative
data
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