162 research outputs found
How Preserving Biodiversity Mitigates the Impacts of Small-scale Land Grab on Livelihoods and Agricultural Production in Central Java
Large-scale land grabbing has had much attention in the literature in recent years, leaving little room for research on small-scale land grabbing and its impacts. Notably, because of the varied contexts in which these small-scale land grabs have happened, few studies have focused on the different mitigation strategies that can either be adopted by communities or are simply inherent in rural communities. This article contributes to filling this gap by presenting a case of small-scale land grab in the highlands of Central Java, and by using a landscape approach within the framework of ecoagriculture. First, the community of Soko Kembang hamlet and the surrounding landscape, located in the subdistrict of Petungkriyono, district of Pekalongan, are described, as well as their multifaceted dynamics. Second, it is shown that the drawbacks in the community brought about by a land grab in 2013, where all rice fields were forcibly sold for a low price to the state electricity enterprise, are somewhat compensated by the benefits associated with a local biodiversity conservation project. More precisely, the agroforestry systems promoted within this project are sustained harmoniously with the natural environment and its primate populations, while being directly beneficial to the community. Thus, although this mitigation strategy has not been adopted directly in response to the rice fields grab, this study shows how complex socio-ecological systems can help enhance the resilience of rural communities in the face of social disturbances. And it also shows how an analysis based on a landscape approach, more precisely within the framework of ecoagriculture in this very case, can shed some light on such complex systems
The ERP correlates of self-knowledge: Are assessments of one’s past, present, and future traits closer to semantic or episodic memory?
Self-knowledge concerns one’s own preferences and personality. It pertains to the self (similar to episodic memory), yet does not concern events. It is factual (like semantic memory), but also idiosyncratic. For these reasons, it is unclear where self-knowledge might fall on a continuum in relation to semantic and episodic memory. In this study, we aimed to compare the event-related potential (ERP) correlates of self-knowledge to those of semantic and episodic memory, using N400 and Late Positive Component (LPC) as proxies for semantic and episodic processing, respectively. We considered an additional factor: time perspective. Temporally distant selves have been suggested to be more semantic compared to the present self, but thinking about one’s past and future selves may also engage episodic memory. Twenty-eight adults answered whether traits (e.g., persistent) were true of most people holding an occupation (e.g. soldiers; semantic memory condition), or true of themselves 5 years ago, in the present, or 5 years from now (past, present, and future self-knowledge conditions). The study ended with an episodic recognition memory task for previously seen traits. Present self-knowledge produced mean LPC amplitudes at posterior parietal sites that fell between semantic and episodic memory. Mean LPC amplitudes for past and future self-knowledge were greater than for semantic memory, and not significantly different from episodic memory. Mean N400 amplitudes for the self-knowledge conditions were smaller than for semantic memory at sagittal sites. However, this N400 effect was not separable from a preceding P200 effect at these same electrode sites. This P200 effect can be interpreted as reflecting the greater emotional salience of self as compared to general knowledge, which may have facilitated semantic processing. Overall, our findings are consistent with a distinction between knowledge of others and self-knowledge, but the closeness of self-knowledge’s neural correlates to either semantic or episodic memory appears to depend to some extent on time perspective
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A Missense Mutation (Q279R) in the Fumarylacetoacetate Hydrolase Gene, Responsible for Hereditary Tyrosinemia, Acts as a Splicing Mutation
Background: Tyrosinemia type I, the most severe disease of the tyrosine catabolic pathway is caused by a deficiency in fumarylacetoacetate hydrolase (FAH). A patient showing few of the symptoms associated with the disease, was found to be a compound heterozygote for a splice mutation, IVS6-1g->t, and a putative missense mutation, Q279R. Analysis of FAH expression in liver sections obtained after resection for hepatocellular carcinoma revealed a mosaic pattern of expression. No FAH was found in tumor regions while a healthy region contained enzymeexpressing nodules. Results: Analysis of DNA from a FAH expressing region showed that the expression of the protein was due to correction of the Q279R mutation. RT-PCR was used to assess if Q279R RNA was produced in the liver cells and in fibroblasts from the patient. Normal mRNA was found in the liver region where the mutation had reverted while splicing intermediates were found in nonexpressing regions suggesting that the Q279R mutation acted as a splicing mutation in vivo. Sequence of transcripts showed skipping of exon 8 alone or together with exon 9. Using minigenes in transfection assays, the Q279R mutation was shown to induce skipping of exon 9 when placed in a constitutive splicing environment. Conclusion: These data suggest that the putative missense mutation Q279R in the FAH gene acts as a splicing mutation in vivo. Moreover FAH expression can be partially restored in certain liver cells as a result of a reversion of the Q279R mutation and expansion of the corrected cells
La durabilité de deux systèmes intégrés d'agriculture et d'aquaculture adoptés dans le delta du Mékong au Vietnam : étude de cas
Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de Montréal
Analyse géographique de la vulnérabilité de la population associée aux inondations dans trois municipalités québécoises : Châteauguay, Montmagny et Sainte-Brigitte-de-Laval
Dans un contexte d'amplification d'évènements climatiques majeurs, la population fait face à différents impacts négatifs, touchant autant leur bien-être que leur environnement. Ce mémoire de maîtrise consiste à réaliser une analyse géographique de la vulnérabilité de la population québécoise face aux inondations. Une analyse plus approfondie est effectuée sur les municipalités de Châteauguay, Montmagny et Sainte-Brigitte-de-Laval. Jusqu'à ce jour, peu d'indicateurs étaient disponibles pour analyser la vulnérabilité de la population face à cet aléa climatique à l'échelle du Québec. Cette étude permet d'identifier et d'analyser les zones vulnérables aux inondations à l'échelle des municipalités québécoises. Dans le but de cartographier ces phénomènes, la sélection de variables retenues d'après une revue de littérature, la création d'indicateurs synthétiques et d'une cartographie synthétique de la vulnérabilité sont primordiales. La mise en place d'une cartographie participative auprès des acteurs municipaux a été effectuée afin de connaître la situation spécifique des municipalités face aux inondations et de valider les résultats obtenus lors de l'élaboration des indicateurs synthétiques. Cette recherche, autant au niveau méthodologique que cartographique, se base sur deux dimensions de la vulnérabilité, soit la sensibilité et la capacité à faire face. À terme, cette étude a permis de mettre en évidence les zones se retrouvant dans une situation de vulnérabilité à la survenue de cet aléa climatique extrême, correspondant ainsi aux zones sensibles et où la capacité à faire face aux inondations est moindre. Mots-clés : Vulnérabilité, inondation, sensibilité, capacité à faire face, cartographie, municipalités québécoises
Synthétiseur de fréquences RF destiné aux dispositifs médicaux implantables
RÉSUMÉ Les microsystèmes biomédicaux implantables présentent un énorme potentiel pour la recherche
médicale. Les dispositifs médicaux intelligents implantables, qui combinent des capteurs et/ou des
actuateurs avec des circuits intégrés, ouvrent la voie à des applications fascinantes. Aujourd’hui,
la possibilité d’utiliser la technologie CMOS pour intégrer des circuits RF, numériques, et même
certains types de capteurs sur une même puce, suscite un vif intérêt dans un domaine nouveau : celui
des réseaux de capteurs implantables, ou BSN (Body-Sensor Networks) et leurs applications en
recherche biomédicale. L’implantation dans le corps de tels réseaux de capteurs sans-fils permettrait
de surveiller, détecter ou même combattre différentes maladies, et ce de manière in situ.
Avec des dimensions minimales inférieures à 100 nm, la technologie CMOS représente un choix
viable pour l’implémentation des blocs de bases des circuits intégrés radio-fréquences (Radio-
Frequency Integrated Circuits - RFIC) à faible consommation de puissance. Toutefois, la réduction
de la tension d’alimentation permise dans les procédés CMOS nanométriques, l’impédance de sortie
limitée des transistors disponibles, ainsi que les variations de procédés ont pour conséquence que
plusieurs architectures de circuits analogiques n’offrent plus les performances requises ou ne sont
tout simplement plus applicables. Des méthodes de conception innovatrices doivent être utilisées
et des compromis judicieux doivent être faits afin de maintenir les performances requises.
Dans un système de communication sans-fil, l’oscillateur local (Local Oscillator - LO) est l’un
des modules les plus importants puisqu’il sert à générer la porteuse du lien RF qui sera par la
suite modulée pour transmettre les données. Dans un contexte où la consommation de puissance
doit être strictement minimisée, la génération d’une fréquence porteuse RF stable dans un procédé
CMOS nanométrique présente des défis énormes. Dans cette optique, cette thèse se concentre sur la
conception, l’analyse, ainsi que sur l’implémentation de circuits analogiques et RF à basse tension
faisant partie d’un synthétiseur de fréquences à consommation ultra faible utilisant un procédé
CMOS nanométrique.
Tout d’abord, une nouvelle architecture de miroir de courant présentant une impédance de sortie
très élevée destiné aux applications à faible tension d’alimentation est présentée. Ce miroir de
courant de faible complexité présente une résistance de sortie très élevée et ce pour des tensions
de sortie s’approchant des alimentations. Ensuite, une nouvelle architecture de pompe de charges
CMOS destinée aux boucles à verrouillage de phase à faible tension et faible puissance est proposée
afin de contourner les difficultés causées par la basse tension d’alimentation et la faible impédance
de sortie des transistors nanométriques.----------ABSTRACT
Implantable biomedical microsystems present a huge potential for medical research. The recent possibility to use CMOS technology to integrate radio-frequency (RF) circuits, baseband signal processing, and even sensors on a same chip has led to a tremendous growth of interest in wireless sensors and their applications. Such microsystems typically include a microprocessor and memory, an energy source, one or more sensors, an analog-to-digital converter (ADC), and a RF transceiver to communicate with a remote base-station or processing unit. In the biomedical field, it is expected that implanting such wireless sensing microsystems could greatly help the medical research
community in learning about the progression of some diseases and assess degree of response to
treatment. With a minimum feature size that has reduced under 100 nm, CMOS technology has become a
viable choice for the implementation of low-power radio-frequency integrated circuits (RFIC) building
blocks. However, the reduction of the supply voltage combined with the low output impedance of nanometer transistors have caused many analog and RF circuit solutions to be unsuitable, or even unusable due to voltage headroom constraints. Therefore, new circuit techniques and innovative design approaches are needed in order to meet the required performance level while maintaining low
power consumption. In a wireless communications system, the local oscillator (LO) is one of the most important building
blocks since it generates the RF carrier signal upon which data is modulated for transmission. In a context where power consumption must be strictly minimized, the generation of a stable RF carrier using a nanometer CMOS process presents huge challenges. In this regard, this thesis focuses on the design, the analysis and the implementation of low-voltage analog and RF circuits used to build an ultra-low power integer-N frequency synthesizer.
First, a new current mirror architecture dedicated to low-voltage, low-power applications is presented. The proposed current mirror offers a very high output resistance and an enhanced output voltage range in comparison with other current mirrors similar in architecture. Then, a novel charge pump dedicated to low-power low-voltage PLLs is proposed. The design of this circuit was motivated
by the need of a nano-CMOS charge pump that would offer constant current magnitude and minimum current mismatch over a wide range of output voltage, while maintaining power
consumption and complexity level as low as possible. A LC resonator-based voltage-controlled oscillator (LC-VCO) that implements a new technique to reduce the impact of process variation on phase noise and power consumption is presented
Approaches to Global Citizenship
James Tully, University of Virginia, describes two different yet overlapping modes of global citizenship which he calls liberal and democratic global citizenship. More information ...
Respondent: Louis-Philippe Hodgson, York University, Dept. of Philosoph
Approaches to Global Citizenship
James Tully, University of Virginia, describes two different yet overlapping modes of global citizenship which he calls liberal and democratic global citizenship. More information ...
Respondent: Louis-Philippe Hodgson, York University, Dept. of Philosoph
Les besoins informationnels en gestion de la production dans les PME : une approche autodiagnostique assisté par ordinateur
Operations management in manufacturing SMEs is becoming more complex and demanding (just-in-time, ISO 9000). For managers, this implies increased information needs that only computer-based systems can adequately satisfy. This article presents a prototype computer-based tool for the self-diagnostic of these needs, including the justification of the approach, strategy and method of analysis used, and its experimentation in two enterprises
Personal semantics: Is it distinct from episodic and semantic memory? An electrophysiological study of memory for autobiographical facts and repeated events in honor of Shlomo Bentin
Declarative memory is thought to consist of two independent systems: episodic and semantic. Episodic memory represents personal and contextually unique events, while semantic memory represents culturally-shared, acontextual factual knowledge. Personal semantics refers to aspects of declarative memory that appear to fall somewhere in between the extremes of episodic and semantic. Examples include autobiographical knowledge and memories of repeated personal events. These two aspects of personal semantics have been studied little and rarely compared to both semantic and episodic memory. We recorded the event-related potentials (ERPs) of 27 healthy participants while they verified the veracity of sentences probing four types of questions: general (i.e., semantic) facts, autobiographical facts, repeated events, and unique (i.e., episodic) events. Behavioral results showed equivalent reaction times in all 4 conditions. True sentences were verified faster than false sentences, except for unique events for which no significant difference was observed. Electrophysiological results showed that the N400 (which is classically associated with retrieval from semantic memory) was maximal for general facts and the LPC (which is classically associated with retrieval from episodic memory) was maximal for unique events. For both ERP components, the two personal semantic conditions (i.e., autobiographical facts and repeated events) systematically differed from semantic memory. In addition, N400 amplitudes also differentiated autobiographical facts from unique events. Autobiographical facts and repeated events did not differ significantly from each other but their corresponding scalp distributions differed from those associated with general facts. Our results suggest that the neural correlates of personal semantics can be distinguished from those of semantic and episodic memory, and may provide clues as to how unique events are transformed to semantic memory
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