Research on Gambling Agreement in Private Equity Financing

Due to the high threshold requirements of applying for a large number of loans from banks, more and more small and medium-sized enterprises have chosen private placement to raise funds, and the betting agreements have been signed to protect the interests of both enterprises and investors. This paper analyzes the case that the bet agreement was applied by Mengniu Dairy and Morgan Stanley in private equity financing. It firstly expounds its background and financing process at that time, then explores why Mengniu Dairy can bet successfully. Finally, countermeasures and suggestions are put forward to promote success of the gambling agreement in private equity especially for small and medium-sized enterprises

Long-Term Sphere Culture Cannot Maintain a High Ratio of Cancer Stem Cells: A Mathematical Model and Experiment

Acquiring abundant and high-purity cancer stem cells (CSCs) is an important prerequisite for CSC research. At present, researchers usually gain high-purity CSCs through flow cytometry sorting and expand them by short-term sphere culture. However, it is still uncertain whether we can amplify high-purity CSCs through long-term sphere culture. We have proposed a mathematical model using ordinary differential equations to derive the continuous variation of the CSC ratio in long-term sphere culture and estimated the model parameters based on a long-term sphere culture of MCF-7 stem cells. We found that the CSC ratio in long-term sphere culture presented as gradually decreased drift and might be stable at a lower level. Furthermore, we found that fitted model parameters could explain the main growth pattern of CSCs and differentiated cancer cells in long-term sphere culture

Real-time Monitoring for the Next Core-Collapse Supernova in JUNO

Core-collapse supernova (CCSN) is one of the most energetic astrophysical events in the Universe. The early and prompt detection of neutrinos before (pre-SN) and during the SN burst is a unique opportunity to realize the multi-messenger observation of the CCSN events. In this work, we describe the monitoring concept and present the sensitivity of the system to the pre-SN and SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), which is a 20 kton liquid scintillator detector under construction in South China. The real-time monitoring system is designed with both the prompt monitors on the electronic board and online monitors at the data acquisition stage, in order to ensure both the alert speed and alert coverage of progenitor stars. By assuming a false alert rate of 1 per year, this monitoring system can be sensitive to the pre-SN neutrinos up to the distance of about 1.6 (0.9) kpc and SN neutrinos up to about 370 (360) kpc for a progenitor mass of 30$M_{\odot}$ for the case of normal (inverted) mass ordering. The pointing ability of the CCSN is evaluated by using the accumulated event anisotropy of the inverse beta decay interactions from pre-SN or SN neutrinos, which, along with the early alert, can play important roles for the followup multi-messenger observations of the next Galactic or nearby extragalactic CCSN.Comment: 24 pages, 9 figure

Research on Gambling Agreement in Private Equity Financing

Due to the high threshold requirements of applying for a large number of loans from banks, more and more small and medium-sized enterprises have chosen private placement to raise funds, and the betting agreements have been signed to protect the interests of both enterprises and investors. This paper analyzes the case that the bet agreement was applied by Mengniu Dairy and Morgan Stanley in private equity financing. It firstly expounds its background and financing process at that time, then explores why Mengniu Dairy can bet successfully. Finally, countermeasures and suggestions are put forward to promote success of the gambling agreement in private equity especially for small and medium-sized enterprises