Tarrajeo exterior según el avance estructural para incrementar la productividad en una edificación de altura, distrito san miguel año 2019

La presente investigación lleva por título “Tarrajeo Exterior según el avance estructural para incrementar la productividad en una edificación de altura, distrito San Miguel año 2019” cuyo objetivo principal fue determinar el incremento de la productividad al realizar la ejecución simultánea de las partidas de edificación estructural, albañilería y tarrajeo exterior, aplicando las herramientas de lean construction tales como carta de balance, trenes de trabajo y contar con un adecuado y continuo proceso constructivo. Con lo que se logró mejorar el rendimiento, determinando el rendimiento de la mano de obra en base a la duración de la ejecución de la partida y el análisis del costo real total de la partida de tarrajeo sin considerar equipo de andamios colgantes. La presente tesis tuvo el método de investigación, deductivo, de orientación aplicada, de enfoque mixto, la fuente de recolección de datos es retroelectivo y de tipo descriptivo, correlacional y explicativo con un diseño de investigación no experimental y según el número de mediciones es transversal. La población estuvo delimitada por la edificación residencial estudiantil “MODO” de Lima Metropolitana y la muestra se determinó a través de un método estadístico cumpliendo con los criterios de inclusión y exclusión. Para esta investigación se logró incrementar la productividad en un 41.24%, el tiempo que demandó las actividades del proceso constructivo de todos los sectores evaluados el cual fue de 177 días y el costo real fue de 103’320.43 soles considerando solo el costo de la mano de obra el cual fue 93’568.43 soles y el costo de los materiales fue 9’752.01 soles usados en la partida de tarrajeo exterior.Tesi

Tarrajeo exterior según el avance estructural para incrementar la productividad en una edificación de altura, distrito San Miguel año 2019

La presente investigación lleva por título “Tarrajeo Exterior según el avance estructural para incrementar la productividad en una edificación de altura, distrito San Miguel año 2019” cuyo objetivo principal fue determinar el incremento de la productividad al realizar la ejecución simultánea de las partidas de edificación estructural, albañilería y tarrajeo exterior, aplicando las herramientas de lean construction tales como carta de balance, trenes de trabajo y contar con un adecuado y continuo proceso constructivo. Con lo que se logró mejorar el rendimiento, determinando el rendimiento de la mano de obra en base a la duración de la ejecución de la partida y el análisis del costo real total de la partida de tarrajeo sin considerar equipo de andamios colgantes. La presente tesis tuvo el método de investigación, deductivo, de orientación aplicada, de enfoque mixto, la fuente de recolección de datos es retroelectivo y de tipo descriptivo, correlacional y explicativo con un diseño de investigación no experimental y según el número de mediciones es transversal. La población estuvo delimitada por la edificación residencial estudiantil “MODO” de Lima Metropolitana y la muestra se determinó a través de un método estadístico cumpliendo con los criterios de inclusión y exclusión. Para esta investigación se logró incrementar la productividad en un 41.24%, el tiempo que demandó las actividades del proceso constructivo de todos los sectores evaluados el cual fue de 177 días y el costo real fue de 103’320.43 soles considerando solo el costo de la mano de obra el cual fue 93’568.43 soles y el costo de los materiales fue 9’752.01 soles usados en la partida de tarrajeo exterior.Tesi

Long-range transportation of polyclic aromatic hydrocarbons and nitropolycyclic aromatic hydrocarbons from China to Japan

金沢大学大学院自然科学研究科Promoting Environmental Pesearch in Pan-Japan Sea Area : Young Researchers\u27 Network, Schedule: March 8-10,2006,Kanazawa Excel Hotel Tokyu, Japan, Organized by: Kanazawa University 21st-Century COE Program, Environmental Monitoring and Prediction of Long- & Short- Term Dynamics of Pan-Japan Sea Area ; IICRC(Ishikawa International Cooperation Research Centre), Sponsors : Japan Sea Research ; UNU-IAS(United Nations University Institute of Advanced Studies)+Ishikawa Prefecture Government ; City of Kanazaw

Atmospheric behaviors of polycyclic aromatic hydrocarbons at a Japanese remote background site, Noto peninsula, from 2004 to 2014

Total suspended particulates were collected at a Japanese remote background site (Noto Air Monitoring Station; NAMS) on the Noto Peninsula from September 2004 to June 2014. Nine polycyclic aromatic hydrocarbons (PAHs) in the particulates (fluoranthene, pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, benzo[ghi]perylene and indeno[1,2,3-cd]pyrene) were determined by HPLC with fluorescence detection. The mean total concentrations of the nine PAHs in the cold season (November to May for the years 2004-2014) was 670 pg m-3 (range 37-4100 pg m-3). The mean total concentration in the warm season (June to October for the same period) was 170 pg m-3 (range 31-960 pg m-3). The atmospheric PAH level at NAMS decreased in recent years, although no significant change was found in the warm season. An analysis of meteorological conditions showed that the atmospheric PAHs at NAMS were long range transported from Northeast China in the cold seasons and were contributed to by Japanese domestic sources in the warm seasons. Lower concentration ratios of reactive PAHs to their isomers at NAMS also supported these results. Activities associated with the Beijing Olympic and Paralympic Games in 2008 and reconstruction after the 2007 Noto Hanto earthquake may have contributed to the yearly variations of atmospheric PAH levels at NAMS during the period 2007-2009. Source control measures implemented by the Chinese and Japanese governments appear to have been effective in decreasing the atmospheric PAH levels at NAMS in recent years. © 2015 Elsevier Ltd.Embargo Period 24 month

Correlation study of observation data of polycyclic aromatic hydrocarbons and chemical transport model calculation data of other pollutants at Wajima

金沢大学大学院自然科学研究科場所：金沢大学自然科学研究科図書館棟1階，講演会場：図書館棟1階　大会議室，ポスター会場：図書館棟1階12会議室,主催・共催：文部科学省２１世紀COE「環日本海域の環境計測と長期・短期変動予測」， 大気環境学会， 金沢大学工学

Correlation study of observation data of polycyclic aromatic hydrocarbons and chemical transport model calculation data of other pollutants at Wajima

金沢大学大学院自然科学研究科場所：東京大学弥生講堂，共催：文部科学省２１世紀COE「環日本海域の環境計測と長期・短期変動予測」，大気環境学

Antibody stabilization for thermally accelerated deep immunostaining

Antibodies have diverse applications due to their high reaction specificities but are sensitive to denaturation when a higher working temperature is required. We have developed a simple, highly scalable and generalizable chemical approach for stabilizing off-the-shelf antibodies against thermal and chemical denaturation. We demonstrate that the stabilized antibodies (termed SPEARs) can withstand up to 4 weeks of continuous heating at 55 °C and harsh denaturants, and apply our method to 33 tested antibodies. SPEARs enable flexible applications of thermocycling and denaturants to dynamically modulate their binding kinetics, reaction equilibrium, macromolecular diffusivity and aggregation propensity. In particular, we show that SPEARs permit the use of a thermally facilitated three-dimensional immunolabeling strategy (termed ThICK staining), achieving whole mouse brain immunolabeling within 72 h, as well as nearly fourfold deeper penetration with threefold less antibodies in human brain tissue. With faster deep-tissue immunolabeling and broad compatibility with tissue processing and clearing methods without the need for any specialized equipment, we anticipate the wide applicability of ThICK staining with SPEARs for deep immunostaining

Identification of biomarkers in ductal carcinoma in situ of the breast with microinvasion

<p>Abstract</p> <p>Background</p> <p>Widespread use of mammography in breast cancer screening has led to the identification of increasing numbers of patients with ductal carcinoma <it>in situ </it>(DCIS). DCIS of the breast with an area of focal invasion 1 mm or less in diameter is defined as DCIS with microinvasion, DCIS-Mi. Identification of biological differences between DCIS and DCIS-Mi may aid in understanding of the nature and causes of the progression of DCIS to invasiveness.</p> <p>Methods</p> <p>In this study, using resected breast cancer tissues, we compared pure DCIS (52 cases) and DCIS-Mi (28 cases) with regard to pathological findings of intraductal lesions, biological factors, apoptosis-related protein expression, and proliferative capacity through the use of immunohistochemistry and the TdT-mediated dUTP-biotin nick end labeling (TUNEL) method.</p> <p>Results</p> <p>There were no differences in biological factors between DCIS and DCIS-Mi, with respect to levels of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor type 2. The frequency of necrosis and positive expression ratio of survivin and Bax were significantly higher in DCIS-Mi than in DCIS. In addition, apoptotic index, Ki-67 index, and positive Bcl-2 immunolabeling tended to be higher in DCIS-Mi than in DCIS. Multivariate analysis revealed that the presence of necrosis and positive survivin expression were independent factors associated with invasion.</p> <p>Conclusion</p> <p>Compared with DCIS, DCIS-Mi is characterized by a slightly elevated cell proliferation capacity and enhanced apoptosis within the intraductal lesion, both of which are thought to promote the formation of cell necrotic foci. Furthermore, the differential expression of survivin may serve in deciding the response to therapy and may have some prognostic significance.</p

Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort Consortium

Objective: To evaluate the association between body mass index and mortality from overall cardiovascular disease and specific subtypes of cardiovascular disease in east and south Asians. Design: Pooled analyses of 20 prospective cohorts in Asia, including data from 835 082 east Asians and 289 815 south Asians. Cohorts were identified through a systematic search of the literature in early 2008, followed by a survey that was sent to each cohort to assess data availability. Setting: General populations in east Asia (China, Taiwan, Singapore, Japan, and Korea) and south Asia (India and Bangladesh). Participants: 1 124 897 men and women (mean age 53.4 years at baseline). Main outcome measures: Risk of death from overall cardiovascular disease, coronary heart disease, stroke, and (in east Asians only) stroke subtypes. Results: 49 184 cardiovascular deaths (40 791 in east Asians and 8393 in south Asians) were identified during a mean follow-up of 9.7 years. East Asians with a body mass index of 25 or above had a raised risk of death from overall cardiovascular disease, compared with the reference range of body mass index (values 22.5-24.9; hazard ratio 1.09 (95% confidence interval 1.03 to 1.15), 1.27 (1.20 to 1.35), 1.59 (1.43 to 1.76), 1.74 (1.47 to 2.06), and 1.97 (1.44 to 2.71) for body mass index ranges 25.0-27.4, 27.5-29.9, 30.0-32.4, 32.5-34.9, and 35.0-50.0, respectively). This association was similar for risk of death from coronary heart disease and ischaemic stroke; for haemorrhagic stroke, the risk of death was higher at body mass index values of 27.5 and above. Elevated risk of death from cardiovascular disease was also observed at lower categories of body mass index (hazard ratio 1.19 (95% confidence interval 1.02 to 1.39) and 2.16 (1.37 to 3.40) for body mass index ranges 15.0-17.4 and less than 15.0, respectively), compared with the reference range. In south Asians, the association between body mass index and mortality from cardiovascular disease was less pronounced than that in east Asians. South Asians had an increased risk of death observed for coronary heart disease only in individuals with a body mass index greater than 35 (hazard ratio 1.90, 95% confidence interval 1.15 to 3.12). Conclusions: Body mass index shows a U shaped association with death from overall cardiovascular disease among east Asians: increased risk of death from cardiovascular disease is observed at lower and higher ranges of body mass index. A high body mass index is a risk factor for mortality from overall cardiovascular disease and for specific diseases, including coronary heart disease, ischaemic stroke, and haemorrhagic stroke in east Asians. Higher body mass index is a weak risk factor for mortality from cardiovascular disease in south Asians