SUPPORTING ACTIVITIES DALAM SUPPLY CHAIN MANAGEMENT: SUATU LANGKAH AWAL PADA BUMDes RANCABANGO, KECAMATAN TAROGONG KALER, KABUPATEN GARUT

Pengabdian masyarakat yang dilakukan oleh Program Studi Magister Akuntansi Universitas Kristen Maranatha ini bertujuan untuk melanjutkan program pendampingan dalam rangka mengembangkan potensi Badan Usaha Milik Desa (BUMDes) di Desa Rancabango, Kecamatan Tarogong Kaler, Kabupaten Garut, Jawa Barat. Khususnya pada tahun 2021 ini, fokus pendampingan BUMDes dilakukan melalui aktivitas mendesain supply chain management untuk mendistribusikan produk unggulan desa-desa di kota Garut yang rencananya akan didistribusikan ke pihak end-user, termasuk di kota Bandung. Aktivitas desain supply chain ini akan mendorong terbentuknya value chain yang berguna untuk mengidentifikasikan kegiatan utama dalam menciptakan nilai kepada pelanggan dan kegiatan dukungan yang terkait.  Selanjutnya, penciptaan nilai ini memungkinkan struktur biaya dapat dikelola dengan baik untuk menawarkan kemampuan harga yang kompetitif. Selain itu, fungsi atau unsur dalam value chain juga dapat meningkatkan diferensiasi dalam mendukung penetapan harga jual yang lebih tinggi. Melalui program pendampingan ini diharapkan dapat memperkuat kontribusi BUMDES Rancabango bagi penduduk desa. Kata kunci: BUMDes Rancabango, program pendampingan, value chain.   ABSTRACT This community service implemented by the Master of Accountancy program of Maranatha Christian University concentrates to resume the mentoring program in order to develop the potential of Village-Owned Enterprises (BUMDes) in Rancabango Village, Tarogong Kaler District, Garut Regency, West Java. Specifically in year 2021, the plan of assisting BUMDes is to design supply chain management activities in order to distribute superior products to villages in the city of Garut which are arranged to be distributed to end-users, including in the city of Bandung. This supply chain design activity will encourage the formation of a value chain which is useful for identifying key activities in creating value to customers and related-support activities. Furthermore, this value creation allows the cost structure to be properly managed to offer competitive pricing capabilities. In addition, functions or elements in the value chain can also increase differentiation in support of higher selling prices. Through this mentoring program, it is hoped that the contribution of BUMDES Rancabango to the villagers is strenghtened. Keywords: BUMDes Rancabango, mentoring program, value chain

Metformin monotherapy downregulates diabetes-associated inflammatory status and impacts on mortality

Aging is the main risk factor for developing diabetes and other age-related diseases. One of the most common features of age-related comorbidities is the presence of low-grade chronic inflammation. This is also the case of metabolic syndrome and diabetes. At the subclinical level, a pro-inflammatory phenotype was shown to be associated with Type-2 diabetes mellitus (T2DM). This low to mid-grade inflammation is also present in elderly individuals and has been termed inflammaging. Whether inflammation is a component of aging or exclusively associated with age-related diseases in not entirely known. We used clinical data and biological readouts in a group of individuals stratified by age, diabetes status and comorbidities to investigate this aspect. While aging is the main predisposing factor for several diseases there is a concomitant increased level of pro-inflammatory cytokines. DM patients show an increased level of sTNFRll, sICAM-1, and TIMP-1 when compared to Healthy, Non-DM and Pre-DM individuals. These inflammatory molecules are also associated with insulin resistance and metabolic syndrome in Non-DM and pre-DM individuals. We also show that metformin monotherapy was associated with significantly lower levels of inflammatory molecules, like TNF, sTNFRI and sTNFRII, when compared to other monotherapies. Longitudinal follow up indicates a higher proportion of death occurs in individuals taking other monotherapies compared to metformin monotherapy. Together our finding shows that chronic inflammation is present in healthy elderly individuals and exacerbated with diabetes patients. Likewise, metformin could help target age-related chronic inflammation in general, and reduce the predisposition to comorbidities and mortality

Open Problems in DAOs

Decentralized autonomous organizations (DAOs) are a new, rapidly-growing class of organizations governed by smart contracts. Here we describe how researchers can contribute to the emerging science of DAOs and other digitally-constituted organizations. From granular privacy primitives to mechanism designs to model laws, we identify high-impact problems in the DAO ecosystem where existing gaps might be tackled through a new data set or by applying tools and ideas from existing research fields such as political science, computer science, economics, law, and organizational science. Our recommendations encompass exciting research questions as well as promising business opportunities. We call on the wider research community to join the global effort to invent the next generation of organizations

Physiological Correlates of Volunteering

We review research on physiological correlates of volunteering, a neglected but promising research field. Some of these correlates seem to be causal factors influencing volunteering. Volunteers tend to have better physical health, both self-reported and expert-assessed, better mental health, and perform better on cognitive tasks. Research thus far has rarely examined neurological, neurochemical, hormonal, and genetic correlates of volunteering to any significant extent, especially controlling for other factors as potential confounds. Evolutionary theory and behavioral genetic research suggest the importance of such physiological factors in humans. Basically, many aspects of social relationships and social activities have effects on health (e.g., Newman and Roberts 2013; Uchino 2004), as the widely used biopsychosocial (BPS) model suggests (Institute of Medicine 2001). Studies of formal volunteering (FV), charitable giving, and altruistic behavior suggest that physiological characteristics are related to volunteering, including specific genes (such as oxytocin receptor [OXTR] genes, Arginine vasopressin receptor [AVPR] genes, dopamine D4 receptor [DRD4] genes, and 5-HTTLPR). We recommend that future research on physiological factors be extended to non-Western populations, focusing specifically on volunteering, and differentiating between different forms and types of volunteering and civic participation

Ushering in energy regionalism

This dissertation explores the impact of existing regional energy institutions on the much purported Southeast Asian energy market integration (EMI). It seeks to bridge neoliberal espousement of regional energy regimes and institutions with political economy determinants that induce broad cooperation at the supra-state level, specifically probing at institutional factors that could lead states to converge on certain policy points, i.e. attainment of benefits derived from the provision of regional public goods. As such, the regional public goods framework is employed to examine which aspects of EMI should be prioritised on regional agendas that requires greater agency and structure within governance. Taken together, these form a guiding framework to illuminate the impact of institutions and market structures on EMI in ASEAN and the ED.Master of Science (International Political Economy

Exploring the real estate and insurance industry in Metro Manila: Implications of moonlighting and work motivation to employee agility as moderated by self-efficacy and Work from Home

The gig economy has been growing exponentially over the past decade, yet there is little known research on the implications of multiple job holders for employees and businesses alike. The study aims to determine the relationship between moonlighting and work motivation to work agility as moderated by work from home and self-efficacy in the real estate and insurance industry. This study utilized a quantitative research design, particularly, causal-explanatory, descriptive and correlational. Through an online questionnaire, 151 Metro Manila-based real estate and insurance professionals were surveyed. Supplementing this was a qualitative approach by interviewing four (4) subject matter experts. Analysis of data was conducted through descriptive statistics, Pearson’s correlation, linear and multiple regression, analysis of variance, pattern matching, and moderated regression. Findings revealed no moderating effect of working from home and self-efficacy on moonlighting and work motivation on employee agility. This implies that work-from-home and self-efficacy should be improved by real estate and insurance industries to capitalize on moonlighting behavior and improve work motivation to have employee agility. It is recommended that the real estate industry increase its work-from-home setup by incorporating CRM technologies and investing in virtual property showcases. Insurance management can boost motivation via certifications and proper rewards

Qubit Measurement by Multichannel Driving

| openaire: EC/H2020/681311/EU//QUESS | openaire: EC/H2020/795159/EU//NEQCWe theoretically propose and experimentally implement a method of measuring a qubit by driving it close to the frequency of a dispersively coupled bosonic mode. The separation of the bosonic states corresponding to different qubit states begins essentially immediately at maximum rate, leading to a speedup in the measurement protocol. Also the bosonic mode can be simultaneously driven to optimize measurement speed and fidelity. We experimentally test this measurement protocol using a superconducting qubit coupled to a resonator mode. For a certain measurement time, we observe that the conventional dispersive readout yields close to 100% higher average measurement error than our protocol. Finally, we use an additional resonator drive to leave the resonator state to vacuum if the qubit is in the ground state during the measurement protocol. This suggests that the proposed measurement technique may become useful in unconditionally resetting the resonator to a vacuum state after the measurement pulse.Peer reviewe