First Union National Bank v. Florida Department of Revenue, 502 So. 2d 964 (Fla. 1st DCA 1987)

Tax-CORPORATE FRANCHISE TAX-A TAX IN SEARCH OF AN IDENTIT

Transit times and electrical discharge in a steady-state gas activation system

This study deals with the problem of transporting a gas from the core of the Ames Laboratory Research Reactor to the ion source of an electromagnetic isotope separator in a steady-state fashion. The parameters on which this flow depends are ascertained so that the flow may be predictably controlled by a computer. The transit time through the activation line is calculated and confirmed experimentally for nitrogen and xenon. The initiation of an electrical discharge in the low pressure gas by a 60 kv potential is studied as a function of the gas and the gradient length

Herbicide Evaluation in Arkansas Rice, 1997

Weed control is economically important for production of rice, a major crop in Arkansas. These findings summarize efforts of the team of Arkansas scientists working on weed control strategies for rice during 1997. Various technologies were evaluated in field studies at five locations involving the major weed problems and rice production systems used in the state. Results from these studies will add to the arsenal of weed control options for producers. Highlights include synergists and safeners for herbicides to aid in control of propanil-resistant barnyardgrass; herbicides and flooding techniques for control of red rice and other weeds; and the use of transgenic rice cultivars for broadspectrum weed control. The preliminary results reported here generally warrant further testing for more advanced findings and for the labeling of new technologies, and finally are the basis for updating safe, effective, and economical recommendations to Arkansas rice producers

Antenatal and Intrapartum Risk Factors for Use of Emergency and Restorative Medicaid Dental Services for Children

Purpose: To investigate the relationship between antenatal/intrapartum factors and Medicaid use. Methods: Three databases were used: (1) birth records; (2) Medicaid files; and (3) Medicaid dental claims. Results: Children of Caucasian mothers were 34 percent more likely to have more than one restorative claim versus children of African American mothers (odds ratio [OR] equals 1.34, 95 percent confidence interval [95% CI] equals 1.10 to 1.65, P<.005). Children born with low birth weight were 37 percent more likely to have emergency claims (OR equals 1.37, 95% CI equals 1.02 to 1.83, P=.03). The adjusted analysis found that Caucasian mothers had higher odds ratio of having a dental claim than African American mothers (P<.001): 33 percent for a restorative claim and 56 percent for an emergency claim. When race was analyzed, the odds of a restorative claim among African American mothers were 2.5 times higher in children delivered by C-section versus those vaginally delivered (OR equals 2.52, 95% CI equals 1.02-6.2, P<.001). Conclusions: This study found: an association between children of Caucasian mothers and the likelihood of experiencing claims; and a relationship between children born with low birth weight and C-section and the likelihood of use of Medicaid services

Herbicide Evaluation in Arkansas Rice 2000

With the widespread development of resistance to propanil by barnyardgrass, the major weed in rice, research has been intensified in recent years to develop alternative weed control technology to the repeated use of propanil. The use of herbicides is economically important for production of rice. Field experiments are conducted annually in Arkansas to evaluate the activity of developmental and commercial herbicides for selective control of barnyardgrass and other weeds in rice. These experiments serve both industry and Arkansas agriculture by providing information on the selectivity of herbicides still in the developmental stage and by comparing the activity of these new herbicides with that of recommended herbicides

Tumour-derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour-bearing mice

BACKGROUND: Cancer cachexia is a metabolic wasting syndrome that is strongly associated with a poor prognosis. The initiating factors causing fat and muscle loss are largely unknown. Previously, we found that leukaemia inhibitory factor (LIF) secreted by C26 colon carcinoma cells was responsible for atrophy in treated myotubes. In the present study, we tested whether C26 tumour‐derived LIF is required for cancer cachexia in mice by knockout of Lif in C26 cells. METHODS: A C26 Lif null tumour cell line was made using CRISPR‐Cas9. Measurements of cachexia were compared in mice inoculated with C26 vs. C26^Lif−/− tumour cells, and atrophy was compared in myotubes treated with medium from C26 vs. C26^Lif−/− tumour cells. Levels of 25 cytokines/chemokines were compared in serum of mice bearing C26 vs. C26^Lif−/− tumours and in the medium from these tumour cell lines. RESULTS: At study endpoint, C26 mice showed outward signs of sickness while mice with C26^Lif−/− tumours appeared healthy. Mice with C26^Lif−/− tumours showed a 55–75% amelioration of body weight loss, muscle loss, fat loss, and splenomegaly compared with mice with C26 tumours (P < 0.05). The heart was not affected by LIF levels because the loss of cardiac mass was the same in C26 and C^26Lif−/− tumour‐bearing mice. LIF levels in mouse serum was entirely dependent on secretion from the tumour cells. Serum levels of interleukin‐6 and G‐CSF were increased by 79‐fold and 68‐fold, respectively, in C26 mice but only by five‐fold and two‐fold, respectively, in C26^Lif−/− mice, suggesting that interleukin‐6 and G‐CSF increases are dependent on tumour‐derived LIF. CONCLUSIONS: This study shows the first use of CRISPR‐Cas9 knockout of a candidate cachexia factor in tumour cells. The results provide direct evidence for LIF as a major cachexia initiating factor for the C26 tumour in vivo. Tumour‐derived LIF was also a regulator of multiple cytokines in C26 tumour cells and in C26 tumour‐bearing mice. The identification of tumour‐derived factors such as LIF that initiate the cachectic process is immediately applicable to the development of therapeutics to treat cachexia. This is a proof of principle for studies that when carried out in human cells, will make possible an understanding of the factors causing cachexia in a patient‐specific manner.This work was supported by NIAMS R01AR060217 to S. C. K. and R. W. J. and NIAMS R01 R01AR060209 to A. R. J., and by the Dudley Allen Sargent Research Fund. The authors certify that they comply with the ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle: update 2017.40 (R01AR060217 - NIAMS; R01 R01AR060209 - NIAMS; Dudley Allen Sargent Research Fund)Published versio

Herbicide Evaluation in Arkansas Rice, 1998

Weed control is economically important for production of rice, a major crop in Arkansas. These findings summarize efforts of the team of Arkansas scientists working on weed control strategies for rice during 1998. Various technologies were evaluated in field studies involving the major weed problems and rice production systems used in the state. Results from these studies will add to the arsenal of weed control options for producers. The preliminary results reported here generally warrant further testing for more advanced findings and for the labeling of new technologies and, finally, are the basis for updating safe, effective, and economical recommendations to Arkansas rice producers

Modeling Human Cancer-induced Cachexia

Talbert et al. developed an inducible mouse model of cachexia caused by pancreatic cancer. This model exhibits features of the human condition, including the progressive depletion of muscle and adipose tissue associated with tumor progression