Modeling Human Cancer-induced Cachexia

Cuitin˜ o, Maria C.; Dilhoff, Mary E.; Eiferman, Daniel S.; Evans, David C.; Ladner, Katherine J.; Leone, Gustavo W.; Ostrowski, Michael C.; Paleo, Brain; Rajasekerea, Priyani V.; Reiser, Peter J.; Schmidt, Carl R.; Shakya, Reena; Siebert, Melissa; Talbert, Erin E.; Timmers, Cynthia D.; Webb, Amy; Weisleder, Noah

Modeling Human Cancer-induced Cachexia

Authors: Maria C. Cuitin˜ o
Mary E. Dilhoff
Daniel S. Eiferman
David C. Evans
Katherine J. Ladner
Gustavo W. Leone
Michael C. Ostrowski
Brain Paleo
Priyani V. Rajasekerea
Peter J. Reiser
Carl R. Schmidt
Reena Shakya
Melissa Siebert
Erin E. Talbert
Cynthia D. Timmers
Amy Webb
Noah Weisleder
Publication date: 1 January 2019
Publisher: The Research Repository @ WVU

Abstract

Talbert et al. developed an inducible mouse model of cachexia caused by pancreatic cancer. This model exhibits features of the human condition, including the progressive depletion of muscle and adipose tissue associated with tumor progression

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