160 research outputs found
Examining Minimal Important Change of the Self-Assessment Scale of Clinical Reasoning in Occupational Therapy
The purpose of the study was to establish and quantify the minimal important change (MIC) value necessary to determine gains or losses in clinical reasoning during student fieldwork assignments as measured by the Self-Assessment of Clinical Reasoning in Occupational Therapy (SA-CROT). This multicenter prospective longitudinal study was conducted with students on their occupational therapy fieldwork in Japan. Two anchor-based methods were used to estimate the MIC values: a receiver operating characteristic-based method and a predictive modeling-based method. The MIC was adjusted based on the percentage of participants who exhibited improvement. Administered were the SA-CROT and the Global Rating of Change (GRC) scale as an anchor. A total of 111 students from 11 occupational therapy educational programs in Japan responded (response rate 29%). Overall, there was a significant difference (p \u3c .001, effect size was r = .80) in SA-CROT before and after fieldwork, and 81% of students showed improvement in the GRC scale. The adjusted MIC value was 3.69, with 95% confidence interval of 2.29–4.97. This anchor-based, adjusted MIC value is the most reliable value to interpret the changes in SA-CROT before and after fieldwork. The SA-CROT\u27s MIC value can be used as a cut-off point from a learner-centered perspective when considering educational methods and environments in fieldwork
Fluctuated spin-orbital texture of Rashba-split surface states in real and reciprocal space
Spin-orbit interaction (SOI) in low-dimensional systems, namely Rashba
systems and the edge states of topological materials, is extensively studied in
this decade as a promising source to realize various fascinating spintronic
phenomena, such as the source of the spin current and spin-mediated energy
conversion. Here, we show the odd fluctuation in the spin-orbital texture in a
surface Rashba system on Bi/InAs(110)-(21) by spin- and angle-resolved
photoelectron spectroscopy and a numerical simulation based on a
density-functional theory (DFT) calculation. The surface state shows a paired
parabolic dispersion with the spin degeneracy lifted by the Rashba effect.
Although its spin polarization should be fixed in a particular direction based
on the Rashba model, the observed spin polarization varies greatly and even
reverses its sign depending on the wavenumber. DFT calculations also reveal
that the spin directions of two inequivalent Bi chains on the surface change
from nearly parallel (canted-parallel) to anti-parallel in real space in the
corresponding wavevector region. These results point out an oversimplification
of the nature of spin in Rashba and Dirac systems and provide more freedom than
expected for spin manipulation of photoelectrons.Comment: 23 pages, 7 figure
Giantin Affects Golgi Stack Connection
Golgins are a family of Golgi-localized long coiled-coil proteins. The major golgin function is thought to be the tethering of vesicles, membranes, and cytoskeletal elements to the Golgi. We previously showed that knockdown of one of the longest golgins, Giantin, altered the glycosylation patterns of cell surfaces and the kinetics of cargo transport, suggesting that Giantin maintains correct glycosylation through slowing down transport within the Golgi. Giantin knockdown also altered the sizes and numbers of mini Golgi stacks generated by microtubule de-polymerization, suggesting that it maintains the independence of individual Golgi stacks. Therefore, it is presumed that Golgi stacks lose their independence following Giantin knockdown, allowing easier and possibly increased transport among stacks and abnormal glycosylation. To gain structural insights into the independence of Golgi stacks, we herein performed electron tomography and 3D modeling of Golgi stacks in Giantin knockdown cells. Compared with control cells, Giantin-knockdown cells had fewer and smaller fenestrae within each cisterna. This was supported by data showing that the diffusion rate of Golgi membrane proteins is faster in Giantin-knockdown Golgi, indicating that Giantin knockdown structurally and functionally increases connectivity among Golgi cisternae and stacks. This increased connectivity suggests that contrary to the cis-golgin tether model, Giantin instead inhibits the tether and fusion of nearby Golgi cisternae and stacks, resulting in transport difficulties between stacks that may enable the correct glycosylation of proteins and lipids passing through the Golgi
Two-dimensional heavy fermion in a monoatomic-layer Kondo lattice YbCu2
Nakamura T., Sugihara H., Chen Y., et al. Two-dimensional heavy fermion in a monoatomic-layer Kondo lattice YbCu2. Nature Communications 14, 7850 (2023); https://doi.org/10.1038/s41467-023-43662-9.The Kondo effect between localized f-electrons and conductive carriers leads to exotic physical phenomena. Among them, heavy-fermion (HF) systems, in which massive effective carriers appear due to the Kondo effect, have fascinated many researchers. Dimensionality is also an important characteristic of the HF system, especially because it is strongly related to quantum criticality. However, the realization of the perfect two-dimensional (2D) HF materials is still a challenging topic. Here, we report the surface electronic structure of the monoatomic-layer Kondo lattice YbCu2 on a Cu(111) surface observed by synchrotron-based angle-resolved photoemission spectroscopy. The 2D conducting band and the Yb 4f state, located very close to the Fermi level, are observed. These bands are hybridized at low-temperature, forming the 2D HF state, with an evaluated coherence temperature of about 30 K. The effective mass of the 2D state is enhanced by a factor of 100 by the development of the HF state. Furthermore, clear evidence of the hybridization gap formation in the temperature dependence of the Kondo-resonance peak has been observed below the coherence temperature. Our study provides a new candidate as an ideal 2D HF material for understanding the Kondo effect at low dimensions
Voltage-assisted Magnetization Switching in Ultrathin Fe80Co20 Alloy Layers
Growing demands for the voltage-driven spintronic applications with
ultralow-power consumption have led to new interest in exploring the
voltage-induced magnetization switching in ferromagnetic metals. In this study,
we observed a large perpendicular magnetic anisotropy change in Au(001) /
ultrathin Fe80Co20(001) / MgO(001) / Polyimide / ITO junctions, and succeeded
in realizing a clear switching of magnetic easy axis between in-plane and
perpendicular directions. Furthermore, employing a perpendicularly magnetized
film, voltage-induced magnetization switching in the perpendicular direction
under the assistance of magnetic fields was demonstrated. These pioneering
results may open a new window of electric-field controlled spintronics devices
- …