38 research outputs found
Moderately differentiated colorectal adenocarcinoma as a lymph node metastatic phenotype: comparison with well differentiated counterparts
<p>Abstract</p> <p>Background</p> <p>The differences between the metastatic property of moderately (Mod) and well (Wel) differentiated colorectal adenocarcinoma remain unclear. Since Mod is unable to form complete acini, therefore an epithelial-mesenchymal transition (EMT) can occur in that structure. Herein, we hypothesized that Mod metastasizes more easily than the Wel counterparts.</p> <p>Methods</p> <p>The medical records of 283 consecutive patients with Mod (n = 71) or Wel (n = 212) who underwent surgery were reviewed between January 1, 2001, and December 31, 2003, for actual 5-year overall survival. We examined the differences between the clinicopathological characteristics of the Mod and the Wel groups.</p> <p>Results</p> <p>The lymph node involvement (<it>p </it>< 0.0001), lymphatic permeation, venous permeation, depth of invasion, liver metastasis, and carcinomatous peritonitis were significantly higher in the Mod group in comparison to the Wel group. The independent risk factors by a logistic regression analysis for lymph node involvement were as follows: lymphatic permeation, liver metastasis, and Mod (<it>p </it>= 0.0291, Relative Risk of 1.991: 95% Confidence Interval: 1.073-3.697). A Kaplan-Meier survival curve showed that Mod had a trend towards a poor survival (<it>p </it>= 0.0517).</p> <p>Conclusion</p> <p>Mod metastasizes to the lymph nodes more easily in comparison to Wel. Therefore, patients with Mod may be considered the existence of lymph node involvement.</p
Measurements of the and -induced Coherent Charged Pion Production Cross Sections on by the T2K experiment
We report an updated measurement of the -induced, and the first
measurement of the -induced coherent charged pion production
cross section on nuclei in the T2K experiment. This is measured in a
restricted region of the final-state phase space for which
GeV, and , and at a mean
(anti)neutrino energy of 0.85 GeV using the T2K near detector. The measured
CC coherent pion production flux-averaged cross section on
is . The new measurement
of the -induced cross section on is . The results are compatible with both the NEUT
5.4.0 Berger-Sehgal (2009) and GENIE 2.8.0 Rein-Sehgal (2007) model
predictions
Measurements of the νμ and ν¯μ -induced coherent charged pion production cross sections on C12 by the T2K experiment
We report an updated measurement of the
ν
μ
-induced, and the first measurement of the
¯
ν
μ
-induced coherent charged pion production cross section on
12
C
nuclei in the Tokai-to-Kamioka experiment. This is measured in a restricted region of the final-state phase space for which
p
μ
,
π
>
0.2
GeV
,
cos
(
θ
μ
)
>
0.8
and
cos
(
θ
π
)
>
0.6
, and at a mean (anti)neutrino energy of 0.85 GeV using the T2K near detector. The measured
ν
μ
charged current coherent pion production flux-averaged cross section on
12
C
is
(
2.98
±
0.37
(
stat
)
±
0.31
(
syst
)
+
0.49
−
0.00
(
Q
2
model
)
)
×
10
−
40
cm
2
. The new measurement of the
¯
ν
μ
-induced cross section on
12
C
is
(
3.05
±
0.71
(
stat
)
±
0.39
(
syst
)
+
0.74
−
0.00
(
Q
2
model
)
)
×
10
−
40
cm
2
. The results are compatible with both the NEUT 5.4.0 Berger-Sehgal (2009) and GENIE 2.8.0 Rein-Sehgal (2007) model predictions