Fulde-Ferrell-Larkin-Ovchinnikov state in a perpendicular field of quasi two-dimensional CeCoIn5

A Fulde-Ferrell-Larkin-Ovchinnkov (FFLO) state was previously reported in the quasi-2D heavy fermion CeCoIn5 when a magnetic field was applied parallel to the ab-plane. Here, we conduct 115^In NMR studies of this material in a PERPENDICULAR field, and provide strong evidence for FFLO in this case as well. Although the topology of the phase transition lines in the H-T phase diagram is identical for both configurations, there are several remarkable differences between them. Compared to H//ab, the FFLO region for H perpendicular to the ab-plane shows a sizable decrease, and the critical field separating the FFLO and non-FFLO superconducting states almost ceases to have a temperature dependence. Moreover, directing H perpendicular to the ab-plane results in a notable change in the quasiparticle excitation spectrum within the planar node associated with the FFLO transition.Comment: 5 pages, 3 figure

Beyond homozygosity mapping: family-control analysis based on Hamming distance for prioritizing variants in exome sequencing

A major challenge in current exome sequencing in autosomal recessive (AR) families is the lack of an effective method to prioritize single-nucleotide variants (SNVs). AR families are generally too small for linkage analysis, and length of homozygous regions is unreliable for identification of causative variants. Various common filtering steps usually result in a list of candidate variants that cannot be narrowed down further or ranked. To prioritize shortlisted SNVs we consider each homozygous candidate variant together with a set of SNVs flanking it. We compare the resulting array of genotypes between an affected family member and a number of control individuals and argue that, in a family, differences between family member and controls should be larger for a pathogenic variant and SNVs flanking it than for a random variant. We assess differences between arrays in two individuals by the Hamming distance and develop a suitable test statistic, which is expected to be large for a causative variant and flanking SNVs. We prioritize candidate variants based on this statistic and applied our approach to six patients with known pathogenic variants and found these to be in the top 2 to 10 percentiles of ranks

Demonstration of RedirectedDoors: Manipulating User\u27s Orientation while Opening Doors in Virtual Reality

We present an installation demonstrating the applicability of RedirectedDoors, a redirection technique that occasionally manipulates the user\u27s orientation during door-opening motions. In this demo, the player explores an indoor virtual environment containing doors while wearing a head-mounted display (HMD), and their orientation in reality is manipulated as a function of the door\u27s opening angle. In addition, when the player opens the door by pushing or pulling the doorknob in virtual reality, the corresponding passive haptic feedback is provided by the self-actuated doorknob-type prop. When reaching the goal, they can see the manipulation results by comparing their virtual position with a real landmark position. Consequently, this demo both makes the player\u27s experience more realistic and presents the virtual environment in a comparatively small physical space