Studi Karakteristik Selai Kolang Kaling Markisa dengan Penambahan Pewarna Angkak

Pengolahan selai dengan bahan baku kolang kaling dan buah markisa akan memberikan warna selai yang kurang menarik. Pigmen angkak dapat dijadikan alternatif pewarna alami yang baik dan cukup stabil dimana juga dapat meningkatkan aktivitas antioksidan pada produk. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan dan konsentrasi yang tepat  bubuk angkak terhadap karakteristik selai kolang kaling  markisa. Penelitian dilakukan menggunakan  rancangan acak lengkap (RAL) dengan 5 perlakuan dan 3 kali ulangan. Perlakuan tersebut adalah penambahan bubuk angkak yaitu : A (tanpa (0%)), B (1%), C (2%), D (3%) dan E (4%). Data dianalisis secara statistik dengan menggunakan analisis of varian (ANOVA) dan dilanjutkan dengan Duncan New Multiple Range Test (DNMRT) pada taraf  5%. Hasil penelitian memperlihatkan bahwa  penambahan angkak memberikan  hasil berpengaruh nyata pada hampir semua parameter karakteristik selai yang dianalisis. Penambahan bubuk angkak 1%  (B) merupakan perlakuan terbaik berdasarkan analisis sensori dengan karakteristik sebagai berikut :  kadar air  28,18%, ohue 11,99, aktivitas antioksidan 20,58%  (pada konsentrasi 100.000 ppm), pH 3,65, total padatan terlarut 59,33%, kadar sakarosa 55,42%,  angka lempeng total 1,0 x103 cfu/g dan lovastatin 3,09 ppm

Protocol: systematic review of the association between socio-economic status and survival in adult head and neck cancer

Abstract Background Head and neck cancer incidence is increasing worldwide. Despite overall improvements in survival, numerous studies suggest worse survival in more disadvantaged populations; however, this literature has not been systematically reviewed. The aim of this review is to investigate whether lower compared to higher socioeconomic status (SES) influences survival in head and neck squamous cell cancer (HNSCC) and explore possible explanations for any relationship found. Method A systematic strategy will be used to identify articles, appraise their quality and extract data. Online databases including MEDLINE, Web of Knowledge, ESBCO Host and Scopus will be used to locate observational studies of adults with a primary diagnosis of head and neck cancer in EU15+ countries (15 members of the EU, Australia, Canada, Norway, USA and New Zealand) where the outcomes report associations between SES and survival. This will be augmented by searching for grey literature and through reference lists. Data will be extracted using a standardised form. Study quality will be assessed using the Newcastle Ottawa scale and where possible meta-analysis of the pooled data will be conducted. Discussion This review will quantify the association between SES and survival outcomes for adult head and neck cancer patients in developed countries. The results will help identify gaps in the literature and therefore direct further novel research in the field. Ultimately, this will inform public policy and strategies to reduce the inequalities in HNSCC survival. Systematic review registration PROSPERO CRD42016037019

High-throughput screening of perovskite alloys for piezoelectric performance and thermodynamic stability

We screen a large chemical space of perovskite alloys for systems with optimal properties to accommodate a morphotropic phase boundary (MPB) in their composition-temperature phase diagram, a crucial feature for high piezoelectric performance. We start from alloy end points previously identified in a high-throughput computational search. An interpolation scheme is used to estimate the relative energies between different perovskite distortions for alloy compositions with a minimum of computational effort. Suggested alloys are further screened for thermodynamic stability. The screening identifies alloy systems already known to host an MPB and suggests a few others that may be promising candidates for future experiments. Our method of investigation may be extended to other perovskite systems, e.g., (oxy-)nitrides, and provides a useful methodology for any application of high-throughput screening of isovalent alloy systems

The predictive accuracy of PREDICT: A personalized decision-making tool for southeast Asian women with breast cancer

10.1097/MD.0000000000000593Medicine (United States)948e59

Total Quality Management: Perspective of Saudi Healthcare Organizations

Total Quality Management is essential in the healthcare sector. Delivering good healthcare services is one of the main issues among healthcare organizations. Healthcare customers are satisfied with healthcare providers when their services meet the level of their expectations. Satisfying healthcare customers (both public and private) can be attained through Total Quality Management. This paper highlights the importance of using Total Quality Management in healthcare organizations in the Kingdom of Saudi Arabia (KSA). A review of the implementation of TQM among Saudi healthcare organizations highlighted the challenges faced in the sector. The sustained efforts in improving the service quality in Saudi healthcare have led to remarkable results. However, there are more challenges regarding the quality of services. This paper is helpful for strategic planners, policy makers, and management in the KSA healthcare sector and in other jurisdictions

Phenomenological Lambda-Nuclear Interactions

Variational Monte Carlo calculations for ${_{\Lambda}^4}H$ (ground and excited states) and ${_{\Lambda}^5}He$ are performed to decipher information on ${\Lambda}$-nuclear interactions. Appropriate operatorial nuclear and ${\Lambda}$-nuclear correlations have been incorporated to minimize the expectation values of the energies. We use the Argonne $\upsilon_{18}$ two-body NN along with the Urbana IX three-body NNN interactions. The study demonstrates that a large part of the splitting energy in ${_{\Lambda}^4}H$ ($0^+-1^+$) is due to the three-body ${\Lambda}$ NN forces. $_{\Lambda}^{17}O$ hypernucleus is analyzed using the {\it s}-shell results. $\Lambda$ binding to nuclear matter is calculated within the variational framework using the Fermi-Hypernetted-Chain technique. There is a need to correctly incorporate the three-body ${\Lambda}$ NN correlations for $\Lambda$ binding to nuclear matter.Comment: 18 pages (TeX), 2 figure

PassivelyQ-switched flashlamp pumped Nd:YAG laser using liquid graphene oxide as saturable absorber

The performance of passively Q-switched Nd:YAG laser operating at 1060 nm is demonstrated using liquid graphene oxide (GO) composite solution as saturable absorber for the first time. The Q-switched Nd:YAG laser is pumped by a xenon flashlamp. The GO was prepared using the simplified Hummer's method and then mixed with polyethylene oxide to form a composite solution. The Q-switched pulsed laser operates at wavelength of 1064.5 nm with a threshold pump energy of 33.64 J. The maximum output Q-switched laser energy of 41.6 mJ achieved at the maximum pump energy of 81 J. The corresponding pulse width is 98.67 ns

Measuring reader fatigue in the interpretation of screening digital breast tomosynthesis (DBT)

Objectives:The interpretation of digital breast tomosynthesis (DBT) screening examinations is a complex task for an already overstretched workforce which has the potential to increase pressure on readers leading to fatigue and patient safety issues. Studies in non-medical and medical settings have suggested that changes in blink characteristics can reflect fatigue. The purpose of this study is to investigate the use of blink characteristics as an objective marker of fatigue in readers interpreting DBT breast screening examinations.Methods:Twenty-six DBT readers involved in the UK PROSPECTS trial interpreted a test set of 40 DBT cases while being observed by an eye tracking device from November 2019 to February 2021. Raw data from the eye tracker were collected and automated processing software was used to produce eye blinking characteristics data which were analysed using multiple linear regression statistical models.Results:Of the 26 DBT readers recruited, eye tracking data from 23 participants were analysed due to missing data rendering 3 participants’ data uninterpretable. The mean reading time per DBT case was 2.81 min. There was a statistically significant increase in blinking duration of 0.38 ms/case as the reading session progressed (p < 0.0001). This was the result of a significant decrease in the number of ultra-short blinks lasting ≤50 ms (p = 0.0005) and a significant increase in longer blinks lasting 51–100 ms (p = 0.008).ConclusionChanges in blinking characteristics could serve as objective measures of reader fatigue and may prove useful in the development of DBT reading protocols.Advances in knowledge:Blink characteristics can be used as an objective measure of fatigue; however there is limited evidence of their use in radiological settings. Our study suggests that changes in blink duration and frequency could be used to monitor fatigue in DBT reading sessions

Comorbidity of Common Mental Disorders with Cancer and Their Treatment Gap: Findings from the World Mental Health Surveys

Objective This study aimed to study the comorbidity of common mental disorders (CMDs) and cancer, and the mental health treatment gap among community residents with active cancer, cancer survivors and cancer-free respondents in 13 high-income and 11 low-middle-income countries. Methods Data were derived from the World Mental Health Surveys (N = 66,387; n = 357 active cancer, n = 1373 cancer survivors, n = 64,657 cancer-free respondents). The World Health Organization/Composite International Diagnostic Interview was used in all surveys to estimate CMDs prevalence rates. Respondents were also asked about mental health service utilization in the preceding 12 months. Cancer status was ascertained by self-report of physician\u27s diagnosis. Results Twelve-month prevalence rates of CMDs were higher among active cancer (18.4%, SE = 2.1) than cancer-free respondents (13.3%, SE = 0.2) adjusted for sociodemographic confounders and other lifetime chronic conditions (adjusted odds ratio (AOR) = 1.44, 95% CI 1.05-1.97). CMD rates among cancer survivors (14.6%, SE = 0.9) compared with cancer-free respondents did not differ significantly (AOR = 0.95, 95% CI 0.82-1.11). Similar patterns characterized high-income and low-middle-income countries. Of respondents with active cancer who had CMD in the preceding 12 months, 59% sought services for mental health problems (SE = 5.3). The pattern of service utilization among people with CMDs by cancer status (highest among persons with active cancer, lower among survivors and lowest among cancer-free respondents) was similar in high-income (64.0%, SE = 6.0; 41.2%, SE = 3.0; 35.6%, SE = 0.6) and low-middle-income countries (46.4%, SE = 11.0; 22.5%, SE = 9.1; 17.4%, SE = 0.7). Conclusions Community respondents with active cancer have higher CMD rates and high treatment gap. Comprehensive cancer care should consider both factors