Near-bottom seismic profiling: High lateral variability, anomalous amplitudes, and estimates of attenuation

For almost a decade the Marine Physical Laboratory of Scripps Institution of Oceanography has been conducting near‐bottom geophysical surveys involving quantitative seismic profiling. Operating initially at 4 kHz and more recently at 6 kHz, this system has provided a wealth of fine scale quantitative data on the acoustic properties of ocean sediments. Over lateral distances of a few meters, 7‐dB changes in overall reflected energy as well as 10‐dB changes from individual reflectors have been observed. Anomalously high amplitudes from deep reflectors have been commonly observed, suggesting that multilayer interference is prevalent in records from such pulsed cw profilers. This conclusion is supported by results from sediment core physical property work and related convolution modeling, as well as by the significant differences observed between 4‐ and 6‐kHz profiles. In general, however, lateral consistency has been adequate in most areas surveyed to permit good estimates of acoustic attenuation from returns from dipping reflectors and sediment wedges

Sea Beam Survey of an Active Strike-Slip Fault: The San Clemente Fault in the California Continental Borderland

The San Clemente fault, located in the California Continental Borderland, is an active, northwest trending, right-lateral, wrench fault. Sea Beam data are used to map the major tectonic landforms associated with active submarine faulting in detail unavailable using conventional echo-sounding or seismic reflection data. In the area between North San Clemente Basin and Fortymile Bank, the major late Cenozoic faults are delineated by alignments of numerous tectonic landforms, including scarps, linear trenches, benches, and sags. Character and spatial patterns of these landforms are consistent with dextral wrench faulting, although vertical offsets may be substantial locally. The main trace of the San Clemente fault cuts a straight path directly across the rugged topography of the region, evidence of a steeply dipping fault surface. Basins or sags located at each right step in the en echelon pattern of faults are manifestations of pull-apart basin development in a right-slip fault zone. Seismic reflection profiles show offset reflectors and a graben in late Quaternary turbidites of the Navy Fan, where the fault zone follows a more northerly trend. Modern tectonic activity along the San Clemente fault zone is demonstrated by numerous earthquakes with epicenters located along the fault\u27s trend. The average strike of the San Clemente fault is parallel to the predicted Pacific-North American relative plate motion vector at this location. Therefore we conclude that the San Clemente fault zone is a part of the broad Pacific-North American transform plate boundary and that the southern California region may be considered as a broad shear zone

Sea Beam survey of an active strike‐slip fault: The San Clemente fault in the California Continental Borderland

The San Clemente fault, located in the California Continental Borderland, is an active, northwest trending, right‐lateral, wrench fault. Sea Beam data are used to map the major tectonic landforms associated with active submarine faulting in detail unavailable using conventional echo‐sounding or seismic reflection data. In the area between North San Clemente Basin and Fortymile Bank, the major late Cenozoic faults are delineated by alignments of numerous tectonic landforms, including scarps, linear trenches, benches, and sags. Character and spatial patterns of these landforms are consistent with dextral wrench faulting, although vertical offsets may be substantial locally. The main trace of the San Clemente fault cuts a straight path directly across the rugged topography of the region, evidence of a steeply dipping fault surface. Basins or sags located at each right step in the en echelon pattern of faults are manifestations of pull‐apart basin development in a right‐slip fault zone. Seismic reflection profiles show offset reflectors and a graben in late Quaternary turbidites of the Navy Fan, where the fault zone follows a more northerly trend. Modern tectonic activity along the San Clemente fault zone is demonstrated by numerous earthquakes with epicenters located along the fault\u27s trend. The average strike of the San Clemente fault is parallel to the predicted Pacific‐North American relative plate motion vector at this location. Therefore we conclude that the San Clemente fault zone is a part of the broad Pacific‐North American transform plate boundary and that the southern California region may be considered as a broad shear zone

Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy

AIMS/HYPOTHESIS: Upregulation of the functional beta cell mass is required to match the physiological demands of mother and fetus during pregnancy. This increase is dependent on placental lactogens (PLs) and prolactin receptors, but the mechanisms underlying these events are only partially understood. We studied the mRNA expression profile of mouse islets during pregnancy to gain a better insight into these changes. METHODS: RNA expression was measured ex vivo via microarrays and quantitative RT-PCR. In vivo observations were extended by in vitro models in which ovine PL was added to cultured mouse islets and MIN6 cells. RESULTS: mRNA encoding both isoforms of the rate-limiting enzyme of serotonin biosynthesis, tryptophan hydroxylase (TPH), i.e. Tph1 and Tph2, were strongly induced (fold change 25- to 200-fold) during pregnancy. This induction was mimicked by exposing islets or MIN6 cells to ovine PLs for 24 h and was dependent on janus kinase 2 and signal transducer and activator of transcription 5. Parallel to Tph1 mRNA and protein induction, islet serotonin content increased to a peak level that was 200-fold higher than basal. Interestingly, only a subpopulation of the beta cells was serotonin-positive in vitro and in vivo. The stored serotonin pool in pregnant islets and PL-treated MIN6 cells was rapidly released (turnover once every 2 h). CONCLUSIONS/INTERPRETATION: A very strong lactogen-dependent upregulation of serotonin biosynthesis occurs in a subpopulation of mouse islet beta cells during pregnancy. Since the newly formed serotonin is rapidly released, this lactogen-induced beta cell function may serve local or endocrine tasks, the nature of which remains to be identified