Morphologie des fruits et quelques caractéristiques physique et chimique de l’huile et des tourteaux de Irvingia gabonensis (Irvingiaceae)

Irvingia gabonensis (Irvingiaceae) est un Produit Forestier Non Ligneux (PFNL) connu pour son fruit et son amande comestibles et dont les aspects ethnobotaniques sont largement discutés dans la littérature. Ce travail est une contribution à la caractérisation physique et chimique des fruits de l’espèce du sud-Bénin. Trois (03) formes physiques (cylindrique, sphérique et ellipsoïdale) sont notées da s les fruits collectés à Abomey-Calavi, Sè et Pobè avec une prépondérance des formes cylindriques. Les teneurs en matières grasses sont de l’ordre de 65% et les indices d’acide, d’iode, de peroxyde, de saponification et d’ester déterminés par lesnormes françaises révèlent la bonne qualité des échantillons d’huiles. L’analyse des esters méthyliques des acides gras de l’huile est faite par Chromatographie en Phase Gazeuse (CPG) et montre la prédominance des acides gras saturés (90%) dont les acides myristique C14:0 et laurique C12:0. L’analyse des tourteaux après extraction de l’huile montre une forte proportion de l’azote, du phosphore, du potassium, du magnésium et des protéines totales (20%). Ces tourteaux délipidés pourraient servir à l’assaisonnement des sauces au Bénin avecune bonne valeur nutritionnelle

The Impact of Pyrethroid Resistance on the Efficacy of Insecticide-Treated Bed Nets against African Anopheline Mosquitoes: Systematic Review and Meta-Analysis

Background Pyrethroid insecticide-treated bed nets (ITNs) help contribute to reducing malaria deaths in Africa, but their efficacy is threatened by insecticide resistance in some malaria mosquito vectors. We therefore assessed the evidence that resistance is attenuating the effect of ITNs on entomological outcomes. Methods and Findings We included laboratory and field studies of African malaria vectors that measured resistance at the time of the study and used World Health Organization–recommended impregnation regimens. We reported mosquito mortality, blood feeding, induced exophily (premature exit of mosquitoes from the hut), deterrence, time to 50% or 95% knock-down, and percentage knock-down at 60 min. Publications were searched from 1 January 1980 to 31 December 2013 using MEDLINE, Cochrane Central Register of Controlled Trials, Science Citation Index Expanded, Social Sciences Citation Index, African Index Medicus, and CAB Abstracts. We stratified studies into three levels of insecticide resistance, and ITNs were compared with untreated bed nets (UTNs) using the risk difference (RD). Heterogeneity was explored visually and statistically. Included were 36 laboratory and 24 field studies, reported in 25 records. Studies tested and reported resistance inconsistently. Based on the meta-analytic results, the difference in mosquito mortality risk for ITNs compared to UTNs was lower in higher resistance categories. However, mortality risk was significantly higher for ITNs compared to UTNs regardless of resistance. For cone tests: low resistance, risk difference (RD) 0.86 (95% CI 0.72 to 1.01); moderate resistance, RD 0.71 (95% CI 0.53 to 0.88); high resistance, RD 0.56 (95% CI 0.17 to 0.95). For tunnel tests: low resistance, RD 0.74 (95% CI 0.61 to 0.87); moderate resistance, RD 0.50 (95% CI 0.40 to 0.60); high resistance, RD 0.39 (95% CI 0.24 to 0.54). For hut studies: low resistance, RD 0.56 (95% CI 0.43 to 0.68); moderate resistance, RD 0.39 (95% CI 0.16 to 0.61); high resistance, RD 0.35 (95% CI 0.27 to 0.43). However, with the exception of the moderate resistance category for tunnel tests, there was extremely high heterogeneity across studies in each resistance category (chi-squared test, p<0.00001, I2 varied from 95% to 100%). Conclusions This meta-analysis found that ITNs are more effective than UTNs regardless of resistance. There appears to be a relationship between resistance and the RD for mosquito mortality in laboratory and field studies. However, the substantive heterogeneity in the studies' results and design may mask the true relationship between resistance and the RD, and the results need to be interpreted with caution. Our analysis suggests the potential for cumulative meta-analysis in entomological trials, but further field research in this area will require specialists in the field to work together to improve the quality of trials, and to standardise designs, assessment, and reporting of both resistance and entomological outcomes