535 research outputs found

    On the Fertilization of the Triploid Ginbuna

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    The ferilization process of the gynogenetic triploid ginbuna Carassius auratus langsdorfii were observed histologically. In the triploid female, it has been reported that the sperm nucleus remains in condensed condition throughout the ferilization to first cleavage. This sperm nucleus does not fuse with female pronucleus, producing the all female triploid offsprings gynogenetically. On the other hand, in the present experiment, in some triploid eggs, the penetrated sperm nucleus swells to form male pronucleus. Some of these eggs develop into tetraploid other than triploid fish. On the scale transplantation experiments between these offsprings, in which all of the sperm nuclei had swollen at the time of fertilization, the unidirectional rejection were observed in two combinations. One of these donors was tetraploid and other was triploid. It seems probable that the former unidirectional rejection might be caused by the introduction of paternal genome, and the later might be caused by the recombination of genes at meiosis or the mutation of the donor and/or the host. From these observation, it was ascertained that the offsprings of triploid ginbuna were not always belonging to the same clone but that some of them differenciated their genome during the gametogenesis or early developmental stage.ArticleäżĄć·žć€§ć­Šç†ć­ŠéƒšçŽ€èŠ 19(1): 53-61(1984)departmental bulletin pape

    Stochastic transitions of attractors in associative memory models with correlated noise

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    We investigate dynamics of recurrent neural networks with correlated noise to analyze the noise's effect. The mechanism of correlated firing has been analyzed in various models, but its functional roles have not been discussed in sufficient detail. Aoyagi and Aoki have shown that the state transition of a network is invoked by synchronous spikes. We introduce two types of noise to each neuron: thermal independent noise and correlated noise. Due to the effects of correlated noise, the correlation between neural inputs cannot be ignored, so the behavior of the network has sample dependence. We discuss two types of associative memory models: one with auto- and weak cross-correlation connections and one with hierarchically correlated patterns. The former is similar in structure to Aoyagi and Aoki's model. We show that stochastic transition can be presented by correlated rather than thermal noise. In the latter, we show stochastic transition from a memory state to a mixture state using correlated noise. To analyze the stochastic transitions, we derive a macroscopic dynamic description as a recurrence relation form of a probability density function when the correlated noise exists. Computer simulations agree with theoretical results.Comment: 21 page

    Scrutinizing LSP Dark Matter at the LHC

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    We show that LHC experiments might well be able to determine all the parameters required for a prediction of the present density of thermal LSP relics from the Big Bang era. If the LSP is an almost pure bino we usually only need to determine its mass and the mass of the SU(2) singlet sleptons. This information can be obtained by reconstructing the cascade q~L→χ~20q→ℓ~Rℓq→χ~10ℓ+ℓ−q\tilde{q}_L \to \tilde{\chi}_2^0 q \to \tilde{\ell}_R \ell q \to \tilde{\chi}_1^0 \ell^+ \ell^- q. The only requirement is that mℓ~R<mχ~20m_{\tilde{\ell}_R} < m_{\tilde{\chi}_2^0}, which is true for most of the cosmologically interesting parameter space. If the LSP has a significant higgsino component, its predicted thermal relic density is smaller than for an equal--mass bino. We show that in this case squark decays also produce significant numbers of χ~40\tilde{\chi}_4^0 and χ~2±\tilde{\chi}_2^\pm. Reconstructing the corresponding decay cascades then allows to determine the higgsino component of the LSP

    The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis

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    The spatial and temporal control of polarity is fundamental to the survival of all organisms. Cells define their polarity using highly conserved mechanisms that frequently rely upon the action of small GTPases, such as Ras and Cdc42. Schizosaccharomyces pombe is an ideal system with which to study the control of cell polarity since it grows from defined tips using Cdc42-mediated actin remodeling. Here we have investigated the importance of Ras1-GTPase activity for the coordination of polarized cell growth during fission yeast mating. Following pheromone stimulation, Ras1 regulates both a MAPK cascade and the activity of Cdc42 to enable uni-directional cell growth towards a potential mating partner. Like all GTPases, when bound to GTP, Ras1 adopts an active conformation returning to an inactive state upon GTP-hydrolysis, a process accelerated through interaction with negative regulators such as GAPs. Here we show that, at low levels of pheromone stimulation, loss of negative regulation of Ras1 increases signal transduction via the MAPK cascade. However, at the higher concentrations observed during mating, hyperactive Ras1 mutations promote cell death. We demonstrate that these cells die due to their failure to coordinate active Cdc42 into a single growth zone resulting in disorganized actin deposition and unsustainable elongation from multiple tips. These results provide a striking demonstration that the deactivation stage of Ras signaling is fundamentally important in modulating cell polarity

    Novel soft bending actuator based power augmentation hand exoskeleton controlled by human intention

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    This article presents the development of a soft material power augmentation wearable robot using novel bending soft artificial muscles. This soft exoskeleton was developed as a human hand power augmentation system for healthy or partially hand disabled individuals. The proposed prototype serves healthy manual workers by decreasing the muscular effort needed for grasping objects. Furthermore, it is a power augmentation wearable robot for partially hand disabled or post-stroke patients, supporting and augmenting the fingers’ grasping force with minimum muscular effort in most everyday activities. This wearable robot can fit any adult hand size without the need for any mechanical system changes or calibration. Novel bending soft actuators are developed to actuate this power augmentation device. The performance of these actuators has been experimentally assessed. A geometrical kinematic analysis and mathematical output force model have been developed for the novel actuators. The performance of this mathematical model has been proven experimentally with promising results. The control system of this exoskeleton is created by hybridization between cascaded position and force closed loop intelligent controllers. The cascaded position controller is designed for the bending actuators to follow the fingers in their bending movements. The force controller is developed to control the grasping force augmentation. The operation of the control system with the exoskeleton has been experimentally validated. EMG signals were monitored during the experiments to determine that the proposed exoskeleton system decreased the muscular efforts of the wearer

    Colour reconnection in e+e- -> W+W- at sqrt(s) = 189 - 209 GeV

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    The effects of the final state interaction phenomenon known as colour reconnection are investigated at centre-of-mass energies in the range sqrt(s) ~ 189-209 GeV using the OPAL detector at LEP. Colour reconnection is expected to affect observables based on charged particles in hadronic decays of W+W-. Measurements of inclusive charged particle multiplicities, and of their angular distribution with respect to the four jet axes of the events, are used to test models of colour reconnection. The data are found to exclude extreme scenarios of the Sjostrand-Khoze Type I (SK-I) model and are compatible with other models, both with and without colour reconnection effects. In the context of the SK-I model, the best agreement with data is obtained for a reconnection probability of 37%. Assuming no colour reconnection, the charged particle multiplicity in hadronically decaying W bosons is measured to be (nqqch) = 19.38+-0.05(stat.)+-0.08 (syst.).Comment: 30 pages, 9 figures, Submitted to Euro. Phys. J.

    Determination of alpha_s using Jet Rates at LEP with the OPAL detector

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    Hadronic events produced in e+e- collisions by the LEP collider and recorded by the OPAL detector were used to form distributions based on the number of reconstructed jets. The data were collected between 1995 and 2000 and correspond to energies of 91 GeV, 130-136 GeV and 161-209 GeV. The jet rates were determined using four different jet-finding algorithms (Cone, JADE, Durham and Cambridge). The differential two-jet rate and the average jet rate with the Durham and Cambridge algorithms were used to measure alpha(s) in the LEP energy range by fitting an expression in which order alpah_2s calculations were matched to a NLLA prediction and fitted to the data. Combining the measurements at different centre-of-mass energies, the value of alpha_s (Mz) was determined to be alpha(s)(Mz)=0.1177+-0.0006(stat.)+-0.0012$(expt.)+-0.0010(had.)+-0.0032(theo.) \.Comment: 40 pages, 17 figures, Submitted to Euro. Phys. J.

    Measurement of triple gauge boson couplings from WW production at LEP energies up to 189 GeV

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    A measurement of triple gauge boson couplings is presented, based on W-pair data recorded by the OPAL detector at LEP during 1998 at a centre-of-mass energy of 189 GeV with an integrated luminosity of 183 pb^-1. After combining with our previous measurements at centre-of-mass energies of 161-183 GeV we obtain k_g=0.97 +0.20 -0.16, g_1^z=0.991 +0.060 -0.057 and lambda_g=-0.110 +0.058 -0.055, where the errors include both statistical and systematic uncertainties and each coupling is determined by setting the other two couplings to their SM values. These results are consistent with the Standard Model expectations.Comment: 28 pages, 8 figures, submitted to Eur. Phys. J.
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