Gastrointestinal quality of life in patients with asymptomatic cholelithiasis after laparoscopic cholecystectomy

To assess the outcome of laparoscopic cholecystectomy for asymptomatic cholelithiasis before and after laparoscopic cholecystectomy using a specific quality of life instrument for gastrointestinal disorders in adults : The Gastrointestinal Quality of Life Index (GIQLI) was used to study the quality of life in patients before and after laparoscopic cholecystectomy : Seventy one patients completed the GIQLI questionnaire both preoperatively and after a minimum postoperative follow-up of three months. Mean preoperative score was 126.8±14.07 out of a theoretical maximum score of 144.After three months, the score had significantly improved to 136.6±9.31, close to the range for the normal population. Not only items assessing gastrointestinal symptoms but also the domains of physical, social, and emotional function improved significantly. The most marked improvements were achieved in patients with the lowest preoperative scores. Laparoscopic cholecystectomy significantly improves the quality of life in patients with cholelithiasis who are asymptomatic or have nonspecific gastrointestinal symptoms that cannot be explained by another gastrointestinal pathology.Bu çalısmada asemptomatik kolelitiyazis olgularının ameliyat öncesi ve ameliyat sonrası hayat kalitesi degerlendirilmistir. Hastaların ameliyat öncesi ve sonrası hayat kalitelerinin ölçümü gastrointestinal hayat kalitesi indeksi parametreleri kullanılarak belirlenmistir. Çalısmaya alınan 71 hasta ameliyat öncesi ve ameliyattan en az 3 ay sonra gastrointestinal hayat kalitesi indeksine göre sorgulanmıstır. Preoperatif dönemde ortalama skor 126.8±14.07, 3 ay sonra yapılan sorgulamada ise ortalama 136.6±9.31 olup normal populasyona yakın bir oranda saptanmıstır. (toplam skor 144). Gastrointestinal semptomlarının yanı sıra fiziksel, sosyal ve duygusal durumlarında da anlamlı düzelme gözlenmistir.Düsük skorlu hastalarda bu iyilesmedaha belirgindir. Asemptomatik kolelitiyazisli hastalarda baska gastrointestinal patolojilerle açıklanamayan nonspesifik semptomların laparoskopik kolesistektomiyle iyilesme gösterdigi, hastaların hayat kalitelerinde anlamlı bir artıs oldugu görülmektedir

Renal transizyonel hücreli karsinom için olası serum belirteçleri: Literatürün gözden geçirilmesi ile birlikte bir olgunun sunumu

Üriner sistemin üst bölümünün ürotelyal tümörü, relatif olarak nadir görülen malignitelerden biridir. Prostat ve testis kanserlerine özgü serum belirteçleri bilinmesine rağmen, renal ve ürotelyal tümörler için spesifik belirteçlerin tanımlanmasına ihtiyaç vardır. Bu makalede, yüksek preoperatif serum düzeyine sahip Karsinoembryonik antijen (CEA) ve Eritrosit sedimentasyon hızına (ESR) sahip olgu sunulacaktır. Preoperatif metastazı olmayan hastaya uygulanan radikal nefroüreterektomi operasyonu sonrası, histolojik tanı yüksek grade’li renal pelvis ürotelyal karsinomu olarak rapor edilmiştir. Cerrahi sınırlar negatif olup serum CEA ve ESR düzeyinde postoperatif erken dönemde tamamen düzelme görülmüştür.Urothelial tumors of the upper urinary tract are relatively rare malignancies of urinary system. Despite the presence of specific serum parameters for prostate and testicular cancer, new markers need to be identified for renal and urothelial cancers. We report a case of huge renal pelvis tumor with high serum levels of carcinoembryonic antigen (CEA) and erythrocyte sedimentation rate (ESR). No distant metastasis was evident preoperatively. Radical nephroureterectomy was performed and the tumor was histologically diagnosed as high grade urothelial carcinoma of the renal pelvis. Surgical margins were negative and marked decrease in serum level of CEA and normalization of ESR, were noticed immediately after surgery

Covid-19 Phobia and Psychological Well-Being in Peritoneal Dialysis Patients during the Pandemic Process

Important and compulsory changes in many areas of life, especially the mandatory quarantine that emerged due to the COVID-19 pandemic, negatively affect the mental health of these individuals. In this study, it is aimed to determine the effect of the pandemic process on COVID-19 phobia and the psychological well-being of peritoneal dialysis patients. This study was completed with 83 patients. Data were analyzed with Kolmogorov-Smirnov, Mann-Whitney U test, Kruskal-Wallis one-way analysis of variance and Spearman's rank correlation coefficient. The relational status between the variables was tested by simple linear regression analysis. Among the participants 54.2% were female, and the mean age was 53.52±15.06. It is seen that the mean score of psychological well-being of peritoneal dialysis patients is 34.71±9.71, and the mean total score of COVID-19 phobia is 61.85±17.73. It was determined that the 18.9% variance in psychological well-being in peritoneal dialysis patients was due to coronavirus phobia. Social distance and long-term restrictions and uncertainties brought about by the COVID-19 pandemic process have negatively affected people in terms of coronavirus phobia and psychological well-being. In this process, early diagnosis of peritoneal dialysis patients with coronavirus phobia and arranging appropriate psychological interventions are important.</p

The Effect of Depression and Perceived Social Support Systems on Quality of Life in Dialysis Patients

OBJECTIVE: The aim of this study was to find the effect of depression and perceived social support systems on quality of life in hemodialysis and peritoneal dialysis patients