5,042 research outputs found
On a new conformal functional for simplicial surfaces
We introduce a smooth quadratic conformal functional and its weighted version
where
is the extrinsic intersection angle of the circumcircles of the
triangles of the mesh sharing the edge and is the valence of
vertex . Besides minimizing the squared local conformal discrete Willmore
energy this functional also minimizes local differences of the angles
. We investigate the minimizers of this functionals for simplicial
spheres and simplicial surfaces of nontrivial topology. Several remarkable
facts are observed. In particular for most of randomly generated simplicial
polyhedra the minimizers of and are inscribed polyhedra. We
demonstrate also some applications in geometry processing, for example, a
conformal deformation of surfaces to the round sphere. A partial theoretical
explanation through quadratic optimization theory of some observed phenomena is
presented.Comment: 14 pages, 8 figures, to appear in the proceedings of "Curves and
Surfaces, 8th International Conference", June 201
Homogeneous metamaterial description of localised spoof plasmonics in spiral geometries
It has been recently shown that ultrathin spiral metamaterials can support localized spoof plasmon modes whose resonant wavelength is much larger than the size of the structure. Here, an analytical model is developed to describe the electromagnetic properties of the two-dimensional version of these devices: a perfect conducting wire corrugated by spiral grooves. The emergence of localized spoof plasmons in this geometry is quantitatively investigated. Calculations show that these modes can be engineered through the spiral angle and the number of grooves. The theory also allows us to elucidate the contribution of magnetic and electric localized spoof plasmons to the optical response of these metamaterial devices. Finally, experimental evidence of the existence of these modes in extremely thin textured copper disks is also presented
The Looming Effects of Estrogen in Covid-19: A Rocky Rollout
In the face of the Covid-19 pandemic, an intensive number of studies have been performed to understand in a deeper way the mechanisms behind better or worse clinical outcomes. Epidemiologically, men subjects are more prone to severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) infections than women, with a similar scenario being also stated to the previous coronavirus diseases, namely, SARS-CoV in 2003 and Middle East Respiratory Syndrome coronavirus diseases (MERS-CoV) in 2012. In addition, and despite that aging is regarded as an independent risk factor for the severe form of the disease, even so, women protection is evident. In this way, it has been expected that sex hormones are the main determinant factors in gender differences, with the immunomodulatory effects of estrogen in different viral infections, chiefly in Covid-19, attracting more attention as it might explain the case-fatality rate and predisposition of men for Covid-19 severity. Here, we aim to provide a mini-review and an overview on the protective effects of estrogen in Covid-19. Different search strategies were performed including Scopus, Web of Science, Medline, Pubmed, and Google Scholar database to find relative studies. Findings of the present study illustrated that women have a powerful immunomodulating effect against Covid-19 through the effect of estrogen. This study illustrates that estrogens have noteworthy anti-inflammatory and immuno-modulatory effects in Covid-19. Also, estrogen hormone reduces SARS-CoV-2 infectivity through modulation of pro-inflammatory signaling pathways. This study highlighted the potential protective effect of estrogen against Covid-19 and recommended for future clinical trial and prospective studies to elucidate and confirm this protective effect.NC-M acknowledges the Portuguese Foundation for Science and Technology under the Horizon 2020 Program (PTDC/PSI-GER/28076/2017). HA-k acknowledges medical staff members of Al-Shiffa Medical Center, Baghdad, Iraq for their participations
A new twist on the geometry of gravitational plane waves
The geometry of twisted null geodesic congruences in gravitational plane wave
spacetimes is explored, with special focus on homogeneous plane waves. The role
of twist in the relation of the Rosen coordinates adapted to a null congruence
with the fundamental Brinkmann coordinates is explained and a generalised form
of the Rosen metric describing a gravitational plane wave is derived. The
Killing vectors and isometry algebra of homogeneous plane waves (HPWs) are
described in both Brinkmann and twisted Rosen form and used to demonstrate the
coset space structure of HPWs. The van Vleck-Morette determinant for twisted
congruences is evaluated in both Brinkmann and Rosen descriptions. The twisted
null congruences of the Ozsvath-Schucking,`anti-Mach' plane wave are
investigated in detail. These developments provide the necessary geometric
toolkit for future investigations of the role of twist in loop effects in
quantum field theory in curved spacetime, where gravitational plane waves arise
generically as Penrose limits; in string theory, where they are important as
string backgrounds; and potentially in the detection of gravitational waves in
astronomy.Comment: 60 pages, 2 figures. Extended version with new material on Rosen
geodesics and isometries. Title change
A 120-Mpc Periodicity in the Three-Dimensional Distribution of Galaxy Superclusters
Using a new compilation of available data on galaxy clusters and
superclusters we present evidence for a quasiregular three-dimensional network
of rich superclusters and voids, with the regions of high density separated by
about 120 Mpc. We calculate the power spectrum for clusters of galaxies; it has
a peak on the wavelength equal to the step of the network; the excess in the
amplitude of the spectrum over that of the cold dark matter model is by a
factor of 1.4. The probability that the spectrum can be formed within the
framework of the standard cosmogony is very small. If the cluster distribution
reflects the distribution of all matter (luminous and dark), then there must
exists some hithero unknown process that produces regular structure on large
scales.Comment: Tex, 6 pages, 2 PostScript figures embedded, accepted by Nature on
November 19, 199
Leptogenesis from loop effects in curved spacetime
We describe a new mechanism -- radiatively-induced gravitational leptogenesis -- for generating the matter-antimatter asymmetry of the Universe. We show how quantum loop effects in C and CP violating theories cause matter and antimatter to propagate differently in the presence of gravity, and prove this is forbidden in flat space by CPT and translation symmetry. This generates a curvature-dependent chemical potential for leptons, allowing a matter-antimatter asymmetry to be generated in thermal equilibrium in the early Universe. The time-dependent dynamics necessary for leptogenesis is provided by the interaction of the virtual self-energy cloud of the leptons with the expanding curved spacetime background, which violates the strong equivalence principle and allows a distinction between matter and antimatter. We show here how this mechanism is realised in a particular BSM theory, the see-saw model, where the quantum loops involve the heavy sterile neutrinos responsible for light neutrino masses. We demonstrate by explicit computation of the relevant two-loop Feynman diagrams how the size of the radiative corrections relevant for leptogenesis becomes enhanced by increasing the mass hierarchy of the sterile neutrinos, and show that for realistic phenomenological parameters this mechanism can generate the observed baryon-to-photon ratio of the Universe
Supersymmetric QCD: Exact Results and Strong Coupling
We revisit two longstanding puzzles in supersymmetric gauge theories. The
first concerns the question of the holomorphy of the coupling, and related to
this the possible definition of an exact (NSVZ) beta function. The second
concerns instantons in pure gluodynamics, which appear to give sensible, exact
results for certain correlation functions, which nonetheless differ from those
obtained using systematic weak coupling expansions. For the first question, we
extend an earlier proposal of Arkani-Hamed and Murayama, showing that if their
regulated action is written suitably, the holomorphy of the couplings is
manifest, and it is easy to determine the renormalization scheme for which the
NSVZ formula holds. This scheme, however, is seen to be one of an infinite
class of schemes, each leading to an exact beta function; the NSVZ scheme,
while simple, is not selected by any compelling physical consideration. For the
second question, we explain why the instanton computation in the pure
supersymmetric gauge theory is not reliable, even at short distances. The
semiclassical expansion about the instanton is purely formal; if infrared
divergences appear, they spoil arguments based on holomorphy. We demonstrate
that infrared divergences do not occur in the perturbation expansion about the
instanton, but explain that there is no reason to think this captures all
contributions from the sector with unit topological charge. That one expects
additional contributions is illustrated by dilute gas corrections. These are
infrared divergent, and so difficult to define, but if non-zero give order one,
holomorphic, corrections to the leading result. Exploiting an earlier analysis
of Davies et al, we demonstrate that in the theory compactified on a circle of
radius beta, due to infrared effects, finite contributions indeed arise which
are not visible in the formal limit that beta goes to infinity.Comment: 28 pages, two references added, one typo correcte
Sculpting oscillators with light within a nonlinear quantum fluid
Seeing macroscopic quantum states directly remains an elusive goal. Particles
with boson symmetry can condense into such quantum fluids producing rich
physical phenomena as well as proven potential for interferometric devices
[1-10]. However direct imaging of such quantum states is only fleetingly
possible in high-vacuum ultracold atomic condensates, and not in
superconductors. Recent condensation of solid state polariton quasiparticles,
built from mixing semiconductor excitons with microcavity photons, offers
monolithic devices capable of supporting room temperature quantum states
[11-14] that exhibit superfluid behaviour [15,16]. Here we use microcavities on
a semiconductor chip supporting two-dimensional polariton condensates to
directly visualise the formation of a spontaneously oscillating quantum fluid.
This system is created on the fly by injecting polaritons at two or more
spatially-separated pump spots. Although oscillating at tuneable THz-scale
frequencies, a simple optical microscope can be used to directly image their
stable archetypal quantum oscillator wavefunctions in real space. The
self-repulsion of polaritons provides a solid state quasiparticle that is so
nonlinear as to modify its own potential. Interference in time and space
reveals the condensate wavepackets arise from non-equilibrium solitons. Control
of such polariton condensate wavepackets demonstrates great potential for
integrated semiconductor-based condensate devices.Comment: accepted in Nature Physic
The Effect of Transposable Element Insertions on Gene Expression Evolution in Rodents
Background:Many genomes contain a substantial number of transposable elements (TEs), a few of which are known to be involved in regulating gene expression. However, recent observations suggest that TEs may have played a very important role in the evolution of gene expression because many conserved non-genic sequences, some of which are know to be involved in gene regulation, resemble TEs. Results:Here we investigate whether new TE insertions affect gene expression profiles by testing whether gene expression divergence between mouse and rat is correlated to the numbers of new transposable elements inserted near genes. We show that expression divergence is significantly correlated to the number of new LTR and SINE elements, but not to the numbers of LINEs. We also show that expression divergence is not significantly correlated to the numbers of ancestral TEs in most cases, which suggests that the correlations between expression divergence and the numbers of new TEs are causal in nature. We quantify the effect and estimate that TE insertion has accounted for ~20% (95% confidence interval: 12% to 26%) of all expression profile divergence in rodents. Conclusions:We conclude that TE insertions may have had a major impact on the evolution of gene expression levels in rodents
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