Climate-Vegetation-Feedbacks as a Mechanism for Accelerated Climate Change: The onset of the African Humid Period

Paleo-environmental records and models indicate that the African Humid Period (AHPabruptly ended about 5000-4000 years before present (BP). Some proxies indicate alsan abrupt onset of the AHP between 14,000 and 11,000 BP. How important are local orbitaforcing, ice-sheet forcing, greenhouse gas forcing, and the reorganization of the AtlantiMeridional Overturning Circulation (AMOC) for changes in the African Monsoon/vegetatiosystem? Here we use transient simulations with climate-vegetation models of differencomplexity to identify the factors that control the onset of the African Monsoon/VegetationWe test the following hypothesis:(1) There is no indication for insolation-thresholds for the onset/break of the AHP.(2) Forcing from CO2/ice-sheets significantly controls the climate of North Africa.(3) CO2 fertilization contributes to the vegetation changes over North Africa.(4) A shutdown of the AMOC is as important as orbital insolation for the African Monsoon

Northern Hemisphere interdecadal variability: A coupled air-sea mode

A coupled air–sea mode in the Northern Hemisphere with a period of about 35 years is described. The mode was derived from a multicentury integration with a coupled ocean–atmosphere general circulation model and involves interactions of the thermohaline circulation with the atmosphere in the North Atlantic and interactions between the ocean and the atmosphere in the North Pacific. The authors focus on the physics of the North Atlantic interdecadal variability. If, for instance, the North Atlantic thermohaline circulation is anomalously strong, the ocean is covered by positive sea surface temperature (SST) anomalies. The atmospheric response to these SST anomalies involves a strengthened North Atlantic Oscillation, which leads to anomalously weak evaporation and Ekman transport off Newfoundland and in the Greenland Sea, and the generation of negative sea surface salinity (SSS) anomalies. These SSS anomalies weaken the deep convection in the oceanic sinking regions and subsequently the strength of the thermohaline circulation. This leads to a reduced poleward heat transport and the formation of negative SST anomalies, which completes the phase reversal. The Atlantic and Pacific Oceans seem to be coupled via an atmospheric teleconnection pattern and the interdecadal Northern Hemispheric climate mode is interpreted as an inherently coupled air–sea mode. Furthermore, the origin of the Northern Hemispheric warming observed recently is investigated. The observed temperatures are compared to a characteristic warming pattern derived from a greenhouse warming simulation with the authors’ coupled general circulation model and also with the Northern Hemispheric temperature pattern associated with the 35-yr climate mode. It is shown that the recent Northern Hemispheric warming projects well onto the temperature pattern of the interdecadal mode under consideration

Preserving the measure of compatibility between quantum states

In this paper after defining the abstract concept of compatibility-like functions on quantum states, we prove that every bijective transformation on the set of all states which preserves such a function is implemented by an either unitary or antiunitary operator.Comment: 11 pages, submitted for publicatio

Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation

T cells are nodal players in the adaptive immune response against pathogens and malignant cells. Alternative splicing plays a crucial role in T cell activation, which is analyzed mainly at later time points upon stimulation. Here we have discovered a 2-h time window early after stimulation where optimal splicing efficiency or, more generally, gene expression efficiency is crucial for successful T cell activation. Reducing the splicing efficiency at 4 to 6 h poststimulation significantly impaired murine T cell activation, which was dependent on the expression dynamics of the Egr1-Nab2-interleukin-2 (IL-2) pathway. This time window overlaps the time of peak IL-2 de novo transcription, which, we suggest, represents a permissive time window in which decreased splicing (or transcription) efficiency reduces mature IL-2 production, thereby hampering murine T cell activation. Notably, the distinct expression kinetics of the Egr1-Nab2-IL-2 pathway between mouse and human render human T cells refractory to this vulnerability. We propose that the rational temporal modulation of splicing or transcription during peak de novo expression of key effectors can be used to fine-tune stimulation-dependent biological outcomes. Our data also show that critical consideration is required when extrapolating mouse data to the human system in basic and translational research

The Effect of Flow at Maud Rise on the Sea Ice Cover - Numerical Experiments

The role of seamounts in the formation and evolution of sea ice isinvestigated in a series of numerical experiments with a coupled seaice-ocean model. Bottom topography, stratification and forcing areconfigured for the Maud Rise region in the Weddell Sea. The specificflow regime that develops at the seamount as the combined response tosteady and tidal forcing consists of free and trapped waves and aTaylor column, which is caused by mean flow and tidal flowrectification. The enhanced variability through tidal motion inparticular is capable of modifying the mixed layer above the seamountenough to delay and reduce sea ice formation throughout the winter.The induced sea ice anomaly spreads and moves westward and affects anarea of several 100~000 km$^{2}$. Process studies reveal the complexinteraction between wind, steady and periodic ocean currents: allthree are required in the process of generation of the sea ice andmixed layer anomalies (mainly through tidal flow), their detachmentfrom the topography (caused by steady oceanic flow), and the westwardtranslation of the sea ice anomaly (driven by the time-mean wind)

Nonlinear dimensionality reduction in climate data

Linear methods of dimensionality reduction are useful tools for handling and interpreting high dimensional data. However, the cumulative variance explained by each of the subspaces in which the data space is decomposed may show a slow convergence that makes the selection of a proper minimum number of subspaces for successfully representing the variability of the process ambiguous. The use of nonlinear methods can improve the embedding of multivariate data into lower dimensional manifolds. In this article, a nonlinear method for dimensionality reduction, Isomap, is applied to the sea surface temperature and thermocline data in the tropical Pacific Ocean, where the El Niño-Southern Oscillation (ENSO) phenomenon and the annual cycle phenomena interact. Isomap gives a more accurate description of the manifold dimensionality of the physical system. The knowledge of the minimum number of dimensions is expected to improve the development of low dimensional models for understanding and predicting ENSO

Sensitivity of the Atlantic meridional overturning circulation to South Atlantic freshwater anomalies

The sensitivity of the Atlantic Meridional Overturning Circulation (AMOC) to changes in basin integrated net evaporation is highly dependent on the zonal salinity contrast at the southern border of the Atlantic. Biases in the freshwater budget strongly affect the stability of the AMOC in numerical models. The impact of these biases is investigated, by adding local anomaly patterns in the South Atlantic to the freshwater fluxes at the surface. These anomalies impact the freshwater and salt transport by the different components of the ocean circulation, in particular the basin-scale salt-advection feedback, completely changing the response of the AMOC to arbitrary perturbations. It is found that an appropriate dipole anomaly pattern at the southern border of the Atlantic Ocean can collapse the AMOC entirely even without a further hosing. The results suggest a new view on the stability of the AMOC, controlled by processes in the South Atlantic. <br/

Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy.

The article The hidden therapist: evidence for a central role of music in psychedelic therapy, written by Mendel Kaelen, Bruna Giribaldi, Jordan Raine, Lisa Evans, Christopher Timmerman, Natalie Rodriguez, Leor Roseman, Amanda Feilding, David Nutt, Robin Carhart-Harris, was originally published electronically on the publisher's internet portal