146 research outputs found

    Entrepreneurship Education and Training in a Small Business Context: Insights from the Competence-based Approach

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    The concept of competence, as it is brought into play in current research, is a potentially powerful construct for entrepreneurship education research and practice. Although the concept has been the subject of strong debate in educational research in general, critical analysis of how it has been used, applied and experienced in entrepreneurship education practice is scarce. This article contributes specifically to the discussion of entrepreneurial competence by theoretically unfolding and discussing the concept. Subsequently, the implications of applying a competence-based approach in entrepreneurship education are illustrated and discussed based on analysis of two cases t

    ï»żVisie op integraal advies door een financieel professional aan het mkb

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    De uitdagingen voor het mkb zijn complex, omvangrijk en hangen met elkaar samen. Om als financieel professional het mkb te kunnen faciliteren naar een toekomstbestendig perspectief, is integraal advies noodzakelijk. Dat betekent multidisciplinair adviseren over hoe zowel financiĂ«le als niet-financiĂ«le aspecten in een organisatie met elkaar samenhangen en waarde creĂ«ren. Daarbij gaat het ook over welke risico’s en kansen dit met zich meebrengt en wat de implicaties daarvan zijn voor de korte, middellange en lange termijn – zowel voor de organisatie zelf als haar omgeving, maar vooral ook in interactie met elkaar. Om integraal financieel advies te kunnen geven, zullen financieel professionals geĂŻntegreerd moeten kunnen denken en handelen. Dat vraagt ook om een andere manier van opleiden

    De Meerwaarde van Risicodeling met Toekomstige Generaties Nader Bezien

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    Rapportage van bevindingen van een Netspar werkgroep waar onderzoek is gedaan naar de welvaartswinst van risicodeling met toekomstige generaties. Risicodeling met toekomstige generaties vindt plaats doordat toekomstige deelnemers ook al (deels) worden blootgesteld aan financiële mee- en tegenvallers uit het heden

    Medicinal and ethnoveterinary remedies of hunters in Trinidad

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    BACKGROUND: Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success. RESULTS: Plants used include Piper hispidum, Pithecelobium unguis-cati, Bauhinia excisa, Bauhinia cumanensis, Cecropia peltata, Aframomum melegueta, Aristolochia rugosa, Aristolochia trilobata, Jatropha curcas, Jatropha gossypifolia, Nicotiana tabacum, Vernonia scorpioides, Petiveria alliacea, Renealmia alpinia, Justicia secunda, Phyllanthus urinaria,Phyllanthus niruri,Momordica charantia, Xiphidium caeruleum, Ottonia ovata, Lepianthes peltata, Capsicum frutescens, Costus scaber, Dendropanax arboreus, Siparuma guianensis, Syngonium podophyllum, Monstera dubia, Solanum species, Eclipta prostrata, Spiranthes acaulis, Croton gossypifolius, Barleria lupulina, Cola nitida, Acrocomia ierensis (tentative ID). CONCLUSION: Plant use is based on odour, and plant morphological characteristics and is embedded in a complex cultural context based on indigenous Amerindian beliefs. It is suggested that the medicinal plants exerted a physiological action on the hunter or his dog. Some of the plants mentioned contain chemicals that may explain the ethnomedicinal and ethnoveterinary use. For instance some of the plants influence the immune system or are effective against internal and external parasites. Plant baths may contribute to the health and well being of the hunting dogs

    DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage

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    Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility and premature ageing. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates with ageing. Here we show that the FOXO transcription factor DAF-16 is activated in response to DNA damage during development, whereas the DNA damage responsiveness of DAF-16 declines with ageing. We find that in contrast to its established role in mediating starvation arrest, DAF-16 alleviates DNA-damage-induced developmental arrest and even in the absence of DNA repair promotes developmental growth and enhances somatic tissue functionality. We demonstrate that the GATA transcription factor EGL-27 co-regulates DAF-16 target genes in response to DNA damage and together with DAF-16 promotes developmental growth. We propose that EGL-27/GATA activity specifies DAF-16-mediated DNA damage responses to enable developmental progression and to prolong tissue functioning when DNA damage persists
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