Eye enucleation and exenteration in -cattle: a retrospective study of 38 cases (2013-2020).

INTRODUCTION The study aimed to describe clinical indications for eye enucleation and exenteration, the occurrence of complications and long-term outcome in cattle, and examine owners' attitude towards enucleation and exenteration and their satisfaction with the surgical outcome. Medical records from the two veterinary teaching hospitals in Switzerland were reviewed to identify cattle that underwent unilateral enucleation or exenteration between January 2013 and December 2020. Data extracted included medical history, ocular examination, clinical diagnosis, surgical procedure including anesthesia, suture material and pattern used, complications, and treatment thereof. Long-term follow-up was evaluated via national animal database inquiries to determine survival time and via owners' interviews with the use of a standardized questionnaire that included questions regarding the occurrence of complications and reason for culling, production performances and perceived quality of life after surgery, concerns, factors affecting the decision to proceed with surgery, and general satisfaction with the outcome. Descriptive statistics, Fisher's exact tests and unpaired t-test were used to summarize the data and assess association between variables. Association was considered significant if p < 0,05. Thirty-eight cases were identified, with a median age of 5 years. More than half of the cases (55,3 %) were diagnosed with non-neoplastic ocular lesions represented by severe trauma with loss of globe content, globe rupture with history of infectious keratoconjunctivitis or hypopyon, or congenital malformations. The remaining cases were diagnosed with neoplastic lesions, including ocular squamous cell carcinoma (OSCC), melanoma, or sarcoma. Complications following surgery were reported in 29 % of cases and included postoperative infection and recurrence of OSCC. There was no significant association between ocular diagnosis and the occurrence of postoperative complications or survival time. Surgery did not seem to influence the animals' postoperative production performance or the perceived quality of life. Most owners (92 %) were satisfied with the surgical outcome. The occurrence of postoperative complications leading to increased overall costs and culling was the main reason for lower owner satisfaction

Adsorption of fullerene and azafullerene on Cu(111) studied by electron energy loss spectroscopy

Fullerene and azafullerene films were studied by electron energy loss spectroscopy in reflection geometry. Compared to C60, (C59N)2 multilayers show additional vibrational modes that are characteristic of the dimer structure. The (C59N)2 is semiconductor-like and giant optically allowed excitonic transitions are found in the gap in drastic contrast with C60. The azafullerene monolayer on Cu(111) no longer shows the presence of dimers, indicating monomer adsorption. Similarly to C60, azafullerene molecules in contact with the metal substrate receive a transferred charge between two and three electrons. However, the C59N appears more covalently bound to Cu because it decomposes when heated above 660 K while C60 only desorbs.

Consistent Group and Coset Reductions of the Bosonic String

Dimensional reductions of pure Einstein gravity on cosets other than tori are inconsistent. The inclusion of specific additional scalar and p-form matter can change the situation. For example, a D-dimensional Einstein-Maxwell-dilaton system, with a specific dilaton coupling, is known to admit a consistent reduction on S^2= SU(2)/U(1), of a sort first envisaged by Pauli. We provide a new understanding, by showing how an S^3=SU(2) group-manifold reduction of (D+1)-dimensional Einstein gravity, of a type first indicated by DeWitt, can be broken into in two steps; a Kaluza-type reduction on U(1) followed by a Pauli-type coset reduction on S^2. More generally, we show that any D-dimensional theory that itself arises as a Kaluza U(1) reduction from (D+1) dimensions admits a consistent Pauli reduction on any coset of the form G/U(1). Extensions to the case G/H are given. Pauli coset reductions of the bosonic string on G= (G\times G)/G are believed to be consistent, and a consistency proof exists for S^3=SO(4)/SO(3). We examine these reductions, and arguments for consistency, in detail. The structures of the theories obtained instead by DeWitt-type group-manifold reductions of the bosonic string are also studied, allowing us to make contact with previous such work in which only singlet scalars are retained. Consistent truncations with two singlet scalars are possible. Intriguingly, despite the fact that these are not supersymmetric models, if the group manifold has dimension 3 or 25 they admit a superpotential formulation, and hence first-order equations yielding domain-wall solutions.Comment: Latex, 5 figures, 45 pages, minor correction

Kaluza-Klein and Gauss-Bonnet cosmic strings

We make a systematic investigation of stationary cylindrically symmetric solutions to the five-dimensional Einstein and Einstein-Gauss-Bonnet equations. Apart from the five-dimensional neutral cosmic string metric, we find two new exact solutions which qualify as cosmic strings, one corresponding to an electrically charged cosmic string, the other to an extended superconducting cosmic string surrounding a charged core. In both cases, test particles are deflected away from the singular line source. We extend both kinds of solutions to exact multi-cosmic string solutions.Comment: 26 pages, LaTex, no figure

Solutions of multigravity theories and discretized brane worlds

We determine solutions to 5D Einstein gravity with a discrete fifth dimension. The properties of the solutions depend on the discretization scheme we use and some of them have no continuum counterpart. In particular, we find that the neglect of the lapse field (along the discretized direction) gives rise to Randall-Sundrum type metric with a negative tension brane. However, no brane source is required. We show that this result is robust under changes in the discretization scheme. The inclusion of the lapse field gives rise to solutions whose continuum limit is gauge fixed by the discretization scheme. We find however one particular scheme which leads to an undetermined lapse reflecting the reparametrization invariance of the continuum theory. We also find other solutions, with no continuum counterpart with changes in the metric signature or avoidance of singularity. We show that the models allow a continuous mass spectrum for the gravitons with an effective 4D interaction at small scales. We also discuss some cosmological solutions.Comment: 19 page

Study of (n,xng) reactions on 238U

Prompt-gamma spectroscopy and time-of-flight techniques were used to measure (n,xn gamma) cross-sections on several nuclei of interest for nuclear reactors. Experiments were performed at the GELINA facility which provides a pulsed white neutron beam of maximum energy about 20 MeV. Preliminary results concerning 238U will be presented. This work was supported by PACEN/GEDEPEONand by the European Commission within the Sixth Framework Programme through I3-EFNUDAT (EURATOMcontract no. 036434) and NUDAME (Contract FP6-516487), and within the Seventh Framework Programme through EUFRAT (EURATOM contract no. FP7-211499) and through ANDES (EURATOM contract no. FP7-249671).JRC.D.4-Standards for Nuclear Safety, Security and Safeguard

Boundary Terms and Junction Conditions for Generalized Scalar-Tensor Theories

We compute the boundary terms and junction conditions for Horndeski's panoptic class of scalar-tensor theories, and write the bulk and boundary equations of motion in explicitly second order form. We consider a number of special subclasses, including galileon theories, and present the corresponding formulae. Our analysis opens up of the possibility of studying tunnelling between vacua in generalized scalar-tensor theories, and braneworld dynamics. The latter follows because our results are independent of spacetime dimension.Comment: 13 pages, Equation corrected. Thanks to Tsutomu Kobayashi for informing us of the typ

Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles.

Fibrosis and fat replacement in skeletal muscle are major complications that lead to a loss of mobility in chronic muscle disorders, such as muscular dystrophy. However, the in vivo properties of adipogenic stem and precursor cells remain unclear, mainly due to the high cell heterogeneity in skeletal muscles. Here, we use single-cell RNA sequencing to decomplexify interstitial cell populations in healthy and dystrophic skeletal muscles. We identify an interstitial CD142-positive cell population in mice and humans that is responsible for the inhibition of adipogenesis through GDF10 secretion. Furthermore, we show that the interstitial cell composition is completely altered in muscular dystrophy, with a near absence of CD142-positive cells. The identification of these adipo-regulatory cells in the skeletal muscle aids our understanding of the aberrant fat deposition in muscular dystrophy, paving the way for treatments that could counteract degeneration in patients with muscular dystrophy

INSPEX: Make environment perception available as a portable system

International audienceObstacle avoidance systems for autonomous vehicles combine multiple sensing technologies (i.e. LiDAR, Radar, Ultrasound and Visual) to detect different types of obstacles across the full range of lighting and weather conditions. Sensor data are fused with vehicle orientation (obtained for instance from an Inertial Measurement Unit and/or compass) and navigation subsystems. Power hungry, they require powerful computational capability, which limits their use to high-end vehicles and robots. 2 INSPEX ambition The H2020 INSPEX project plans to make obstacle detection capabilities available as a personal portable multi-sensors, miniaturised, low power device. This device will detect, locate and warn of obstacles under different environmental conditions, in indoor/outdoor environments, with static and mobile obstacles. Potential applications range from safer human navigation in reduced visibility conditions (e.g. for first responders and fire brigades), small robot/drone obstacle avoidance systems to navigation for the visually and mobility impaired people. As primary demonstrator (Fig.1), we will plug the INSPEX device on a white cane (see Fig. 1) for Visually Impaired and Blind (VIB) people to detect obstacle over the whole person height, provide audio feedback about harmful obstacles, improve their mobility confidence and reduce injuries, especially at waist and head levels [1]. The device will offer a "safety cocoon" to its user