472 research outputs found
Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
10.1093/nar/gkp857Nucleic Acids Research381215-22
Measuring the prompt atmospheric neutrino flux with down-going muons in neutrino telescopes
In the TeV energy region and above, the uncertainty in the level of prompt
atmospheric neutrinos would limit the search for diffuse astrophysical
neutrinos. We suggest that neutrino telescopes may provide an empirical
determination of the flux of prompt atmospheric electron and muon neutrinos by
measuring the flux of prompt down-going muons. Our suggestion is based on the
consideration that prompt neutrino and prompt muon fluxes at sea level are
almost identical.Comment: 4 pages, 3 figure
Distinguishing sequences for partially specified FSMs
Distinguishing Sequences (DSs) are used inmany Finite State Machine (FSM) based test techniques. Although Partially Specified FSMs (PSFSMs) generalise FSMs, the computational complexity of constructing Adaptive and Preset DSs (ADSs/PDSs) for PSFSMs has not been addressed. This paper shows that it is possible to check the existence of an ADS in polynomial time but the corresponding problem for PDSs is PSPACE-complete. We also report on the results of experiments with benchmarks and over 8 * 106 PSFSMs. © 2014 Springer International Publishing
Theory and computation of covariant Lyapunov vectors
Lyapunov exponents are well-known characteristic numbers that describe growth
rates of perturbations applied to a trajectory of a dynamical system in
different state space directions. Covariant (or characteristic) Lyapunov
vectors indicate these directions. Though the concept of these vectors has been
known for a long time, they became practically computable only recently due to
algorithms suggested by Ginelli et al. [Phys. Rev. Lett. 99, 2007, 130601] and
by Wolfe and Samelson [Tellus 59A, 2007, 355]. In view of the great interest in
covariant Lyapunov vectors and their wide range of potential applications, in
this article we summarize the available information related to Lyapunov vectors
and provide a detailed explanation of both the theoretical basics and numerical
algorithms. We introduce the notion of adjoint covariant Lyapunov vectors. The
angles between these vectors and the original covariant vectors are
norm-independent and can be considered as characteristic numbers. Moreover, we
present and study in detail an improved approach for computing covariant
Lyapunov vectors. Also we describe, how one can test for hyperbolicity of
chaotic dynamics without explicitly computing covariant vectors.Comment: 21 pages, 5 figure
The Effect of Shadowing on Initial Conditions, Transverse Energy and Hard Probes in Ultrarelativistic Heavy Ion Collisions
The effect of shadowing on the early state of ultrarelativistic heavy ion
collisions is investigated along with transverse energy and hard process
production, specifically Drell-Yan, , and production. We
choose several parton distributions and parameterizations of nuclear shadowing,
as well as the spatial dependence of shadowing, to study the influence of
shadowing on relevant observables. Results are presented for Au+Au collisions
at GeV and Pb+Pb collisions at TeV.Comment: Submitted to Phys. Rev.
Comparison of advanced gravitational-wave detectors
We compare two advanced designs for gravitational-wave antennas in terms of
their ability to detect two possible gravitational wave sources. Spherical,
resonant mass antennas and interferometers incorporating resonant sideband
extraction (RSE) were modeled using experimentally measurable parameters. The
signal-to-noise ratio of each detector for a binary neutron star system and a
rapidly rotating stellar core were calculated. For a range of plausible
parameters we found that the advanced LIGO interferometer incorporating RSE
gave higher signal-to-noise ratios than a spherical detector resonant at the
same frequency for both sources. Spheres were found to be sensitive to these
sources at distances beyond our galaxy. Interferometers were sensitive to these
sources at far enough distances that several events per year would be expected
Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system.
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection. One of the principal factors that control the outcome of infection is the localized tissue response and subsequent immune response directed against the invading toxic agent. It is the role of the immune system to contain and control the spread of virus infection in the central nervous system (CNS), and paradoxically, this response may also be pathologic. Chemokines are potent proinflammatory molecules whose expression within virally infected tissues is often associated with protection and/or pathology which correlates with migration and accumulation of immune cells. Indeed, studies with a neurotropic murine coronavirus, mouse hepatitis virus (MHV), have provided important insight into the functional roles of chemokines and chemokine receptors in participating in various aspects of host defense as well as disease development within the CNS. This chapter will highlight recent discoveries that have provided insight into the diverse biologic roles of chemokines and their receptors in coordinating immune responses following viral infection of the CNS
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