Anti-allergic Activity of Stem Bark of Myrica esculenta Buch.-Ham. (Myricaceae)

Allergic diseases, such as allergic asthma, are hypersensitivity reactions initiated by immunological mechanisms. Myrica esculenta (M. esculenta) is known traditionally in Ayurveda to possess anti-asthmatic activity. The present investigation was undertaken to evaluate the effect of crude extract of stem bark of M. esculenta (Family Myricaceae, commonly known as Kaiphal) on experimental allergic reactions. Experimental models studied were allergic pleurisy and vascular permeability induced by acetic acid in mice. Pretreatment with M. esculenta (75 mg/kg and 150 mg/kg, p.o.) significantly inhibited the eosinophil accumulation (P < 0.01) respectively in the pleural cavity. M. esculenta (75 and 150 mg/kg, p.o.) significantly inhibited the rise in plasma exudation (57.12% and 59.77%, P < 0.01) induced by acetic acid in mice. These findings demonstrate that the crude extract from the stem bark of M. esculenta possesses antiallergic activity. This activity may be mediated by reducing the release of mediators such as histamine, inhibition of mast cell degranulation, and inhibition of eosinophil accumulation thereby preventing the release of cytokines and chemokines

Fair treatment, fair play? The relationship between fair treatment perceptions, political trust and compliant and cooperative attitudes cross‐nationally

Obtaining citizens’ voluntary compliance with political decisions is a fundamental democratic challenge. Fair treatment by public officials plays a key role in theoretical and empirical studies on citizens’ compliance and cooperation. Yet it is unclear whether citizens within different societies react to (un)fair treatment in the same way. Using multilevel structural equation modelling and multilevel regression analysis on the European Social Survey 2010–2 (N = 52,458), this article shows that perceptions of fair treatment by police officers are associated with higher levels of trust in political institutions and in turn stronger compliant and cooperative attitudes of citizens in 27 countries. Yet the link between perceptions of unfair treatment and institutional trust is stronger in countries in which fair behaviour is more prevalent. While fair treatment is often considered to be a universal norm affecting citizens in a uniform way, this article sheds light on important cross‐national variations

The

The Trident laser facility at Los Alamos National Laboratory (LANL) has served for more than 20 years as an important tool in inertial confinement fusion (ICF) and Material Dynamics research. An energy and power upgrade of the short-pulse beam line to 100J / 200 TW was made in 2007 and contrast improvements have been made continually since. The combination of this powerful new short-pulse beamline with the two flexible long pulse beamlines, and a total of three different target areas, makes Trident a highly flexible and versatile research tool for high energy density laboratory plasma (HEDLP) research. The newest “Dial-a-Contrast” (DaC) features are described, along with nominal performance of the laser at the presently available highest contrast

The TRIDENT laser at LANL: New “dial-a-contrast” and high-contrast experimental capabilities

The Trident laser facility at Los Alamos National Laboratory (LANL) has served for more than 20 years as an important tool in inertial confinement fusion (ICF) and Material Dynamics research. An energy and power upgrade of the short-pulse beam line to 100J / 200 TW was made in 2007 and contrast improvements have been made continually since. The combination of this powerful new short-pulse beamline with the two flexible long pulse beamlines, and a total of three different target areas, makes Trident a highly flexible and versatile research tool for high energy density laboratory plasma (HEDLP) research. The newest “Dial-a-Contrast” (DaC) features are described, along with nominal performance of the laser at the presently available highest contrast