16 research outputs found

    Human Disease and Vaccination

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    First phytoplankton community assessment of the Kong Håkon VII Hav, Southern Ocean during austral autumn

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    We studied phyto- and protozooplankton community composition based on light microscopy, flow cytometry and photosynthetic pigment data in the Atlantic sector of the Southern Ocean during March 2019 (early austral autumn). Sampling was focused on the area east of the prime meridian in the Kong Håkon VII Hav, including Astrid Ridge, Maud Rise and a south-north transect at 6° E. Phytoplankton community composition throughout the studied area was characterized by oceanic diatoms typical of the iron-deplete High-Nutrient Low-Chlorophyll (HNLC) Southern Ocean. Topography and wind-driven iron supply likely sustained blooms dominated by the centric diatom Chaetoceros dichaeta at Maud Rise and at a station north of the 6° E transect. For the remainder of the 6° E transect diatom composition was similar to the previously mentioned bloom stations but flagellates dominated in abundance suggesting a post-bloom situation and likely top-down control by krill on the bloom-forming diatoms. Among flagellates, species with haptophyte-type pigments were the dominating group. At Astrid Ridge, overall abundances were lower and pennate were more numerous than centric diatoms, but the community composition was nevertheless typical for HNLC areas. The observations described here show that C. dichaeta can form blooms beyond the background biomass level and fuels both carbon export and upper trophic levels also within HNLC areas. This study is the first thorough assessment of phytoplankton communities in this region and can be compared to other seasons in future studies

    Engano na administração de soro-vacinação para raiva. Emprego de esquema improvisado e sua avaliação: apresentação de um caso An error in administration of serum vaccination for rabies. Use and evaluation of an improvised scheme: a case report

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    Apresentamos registro de caso de paciente agredida por cão que morreu 4 dias depois, e que se apresentou para tratamento 11 dias após o acidente. Foi indicado esquema de soro-vacinação a ser iniciado imediatamente com administração de soro anti-rábico (9ml, correspondente a 40 UI/Kg de peso) e série de 10 doses de vacina aplicadas em dias consecutivos e 3 doses de reforço, com 10 dias de intervalo, conforme normas da Secretaria da Saúde do Estado de São Paulo. Por engano, entretanto, foram aplicadas inicialmente 9 doses de vacina em 3 locais anatômicos diferentes. Verificado o erro de imediato, optamos pela suspensão do tratamento por alguns dias e sua reimplantação completa, o que só foi feito após 8 dias. O seguimento sorológico (pelas provas de soro-neutralização em cultura celular) evidenciou resposta inteiramente satisfatória, superando largamente em níveis, precocidade e duração as recomendações da OMS. A paciente permanecia sadia até o 240º dia após o acidente, quando foi observada pela última vez antes desta publicação.<br>We report on a female patient attacked by a dog that died 4 days later, who sough treatment 11 days after the accident.A serum vaccination schedule was indicated, to be started immediately with the administration of anti-rabies serum (9 ml, corresponding to 40 IU/Kg body weight) and a series of 10 doses of vaccine applied on consecutive days plus 3 booster doses applied at 10-day intervals, according to the regulations of the Health . Secretariat of the State of Sao Paulo. However, due to an error, 9 vaccine doses were iniatially applied at 3 different anatomical sites. The error was immediately discovered and it was decided to interrup treatment for a few days and to restart and complete it later; this was done only 8 days later. Serologic follow-up by the serum-neutralization test in cell culture revealed a fully satisfactory response greatly exceeding WHO recommendations in terms of levels, precocity and duration. The patient continued to be healthy by the 240th day after the accident, when she was observed for the last time before this publication
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