17,485 research outputs found

    Technique of elbow bending small jacketed transfer lines Patent

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    Elbow forming in jacketed pipes while maintaining separation between core shape and jacket pipe

    Dynamic Modulation of the Action Observation Network by Movement Familiarity

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    Contains fulltext : 139821.pdf (publisher's version ) (Open Access)When watching another person's actions, a network of sensorimotor brain regions, collectively termed the action observation network (AON), is engaged. Previous research suggests that the AON is more responsive when watching familiar compared with unfamiliar actions. However, most research into AON function is premised on comparisons of AON engagement during different types of task using univariate, magnitude- based approaches. To better understand the relationship between action familiarity and AON engagement, here we examine how observed movement familiarity modulates AON activity in humans using dynamic causal modeling, a type of effective connectivity analysis. Twenty- one subjects underwent fMRI scanning while viewing whole- body dance movements that varied in terms of their familiarity. Participants' task was to either predict the next posture the dancer's body would assume or to respond to a nonaction- related attentional control question. To assess individuals' familiarity with each movement, participants rated each video on a measure of visual familiarity after being scanned. Parametric analyses showed more activity in left middle temporal gyrus, inferior parietal lobule, and inferior frontal gyrus as videos were rated as increasingly familiar. These clusters of activity formed the regions of interest for dynamic causal modeling analyses, which revealed attenuation of effective connectivity bidirectionally between parietal and temporalAONnodes when participants observed videos they rated as increasingly familiar. As such, the findings provide partial support for a predictive coding model of the AON, as well as illuminate how action familiarity manipulations can be used to explore simulation based accounts of action understanding.12 p

    Fatty-acid uptake in prostate cancer cells using dynamic microfluidic raman technology

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    It is known that intake of dietary fatty acid (FA) is strongly correlated with prostate cancer progression but is highly dependent on the type of FAs. High levels of palmitic acid (PA) or arachidonic acid (AA) can stimulate the progression of cancer. In this study, a unique experimental set-up consisting of a Raman microscope, coupled with a commercial shear-flow microfluidic system is used to monitor fatty acid uptake by prostate cancer (PC-3) cells in real-time at the single cell level. Uptake of deuterated PA, deuterated AA, and the omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were monitored using this new system, while complementary flow cytometry experiments using Nile red staining, were also conducted for the validation of the cellular lipid uptake. Using this novel experimental system, we show that DHA and EPA have inhibitory effects on the uptake of PA and AA by PC-3 cells

    Galaxy Counts, Sizes, Colours and Redshifts in the Hubble Deep Field

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    We compare the galaxy evolution models of Bruzual & Charlot (1993) with the faint galaxy count, size and colour data from the Hubble and Herschel Deep Fields (Metcalfe et al 1996). For qo=0.05, we find that models where the SFR increases exponentially out to z>2 are consistent with all of the observational data. For qo=0.5, such models require an extra population of galaxies which are only seen at high redshift and then rapidly fade or disappear. We find that, whatever the cosmology, the redshift of the faint blue galaxies and hence the epoch of galaxy formation is likely to lie at z>2. We find no implied peak in the SFR at z=1 and we suggest that the reasons for this contradiction with the results of Madau et al (1996) include differences in faint galaxy photometry, in the treatment of spiral dust and in the local galaxy count normalisation.Comment: 8 pages, 5 eps figures, needs paspconf.st

    Submarine landslides on the upper southeast Australian passive continental margin – preliminary findings

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    The southeast Australian passive continental margin is narrow, steep and sediment-deficient, and characterized by relatively low rates of modern sedimentation. Upper slope (\u3c1200m) sediments comprise mixtures of calcareous and terrigenous sand and mud. Three of twelve sediment cores recovered from geologically-recent, submarine landslides located offshore New South Wales/Queensland (NSW/QLD) are interpreted to have sampled failure surfaces at depths of between 85 cm and 220 cm below the present-day seabed. Differences in sediment physical properties are recorded above and below the three slide-plane boundaries. Sediment taken directly above the inferred submarine landslide failure surfaces and presumed to be post-landslide, returned radiocarbon ages of 15.8 ka, 20.7 ka and 20.1 ka. The last two ages correspond to adjacent slide features, which are inferred to be consistent with their being triggered by a single event such as an earthquake. Slope stability models based on classical soil mechanics and measured sediment shearstrengths indicate that the upper slope sediments should be stable. However, multibeam sonar data reveal that many upper slope landslides occur across the margin and that submarine landsliding is a common process. We infer from these results that: a) an unidentified mechanism regularly acts to reduce the shear resistance of these sediments to the very low values required to enable slope failure, and/or b) the margin experiences seismic events that act to destabilise the slope sediments

    OAR BLADE FORCE COEFFICIENTS AND A MATHEMATICAL MODEL OF ROWING

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    The aim of this study was to validate the use of computational fluid dynamics (CFD) to determine oar blade force coefficients for use in a mathematical model of rowing mechanics to predict the performance of a boat. Experimental and CFD derived lift and drag force coefficients for a Macon oar blade were taken from previously published research. Each set of coefficients was used to drive a mathematical model of rowing, and predicted instantaneous and mean steady state boat velocity compared. Instantaneous boat velocity was similar throughout the stroke and mean boat velocity varied by only 1.33%. In conclusion, this investigation has demonstrated that lift and drag coefficients obtained by computational methods may be used successfully to predict boat behaviour in a mathematical model of rowing. The use of computational data closely matches model outputs derived from experimental data

    Diffuse Extragalactic Background Light versus Deep Galaxy Counts in the Subaru Deep Field: Missing Light in the Universe?

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    Deep optical and near-infrared galaxy counts are utilized to estimate the extragalactic background light (EBL) coming from normal galactic light in the universe. Although the slope of number-magnitude relation of the faintest counts is flat enough for the count integration to converge, considerable fraction of EBL from galaxies could still have been missed in deep galaxy surveys because of various selection effects including the cosmological dimming of surface brightness of galaxies. Here we give an estimate of EBL from galaxy counts, in which these selection effects are quantitatively taken into account for the first time, based on reasonable models of galaxy evolution which are consistent with all available data of galaxy counts, size, and redshift distributions. We show that the EBL from galaxies is best resolved into discrete galaxies in the near-infrared bands (J, K) by using the latest data of the Subaru Deep Field; more than 80-90% of EBL from galaxies has been resolved in these bands. Our result indicates that the contribution by missing galaxies cannot account for the discrepancy between the count integration and recent tentative detections of diffuse EBL in the K-band (2.2 micron), and there may be a very diffuse component of EBL which has left no imprints in known galaxy populations.Comment: ApJ Letters in press. Two new reports on the diffuse EBL at 1.25 and 2.2 microns are added to the reference list and Table

    A randomised controlled trial of mentalization-based treatment versus structured clinical management for patients with comorbid borderline personality disorder and antisocial personality disorder.

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    BACKGROUND: Antisocial personality disorder (ASPD) is an under-researched mental disorder. Systematic reviews and policy documents identify ASPD as a priority area for further treatment research because of the scarcity of available evidence to guide clinicians and policymakers; no intervention has been established as the treatment of choice for this disorder. Mentalization-based treatment (MBT) is a psychotherapeutic treatment which specifically targets the ability to recognise and understand the mental states of oneself and others, an ability shown to be compromised in people with ASPD. The aim of the study discussed in this paper is to investigate whether MBT can be an effective treatment for alleviating symptoms of ASPD. METHODS: This paper reports on a sub-sample of patients from a randomised controlled trial of individuals recruited for treatment of suicidality, self-harm, and borderline personality disorder. The study investigates whether outpatients with comorbid borderline personality disorder and ASPD receiving MBT were more likely to show improvements in symptoms related to aggression than those offered a structured protocol of similar intensity but excluding MBT components. RESULTS: The study found benefits from MBT for ASPD-associated behaviours in patients with comorbid BPD and ASPD, including the reduction of anger, hostility, paranoia, and frequency of self-harm and suicide attempts, as well as the improvement of negative mood, general psychiatric symptoms, interpersonal problems, and social adjustment. CONCLUSIONS: MBT appears to be a potential treatment of consideration for ASPD in terms of relatively high level of acceptability and promising treatment effects. TRIAL REGISTRATION: ISRCTN ISRCTN27660668 , Retrospectively registered 21 October 2008

    Static Correlation and Dynamical Properties of Tb3+-moments in Tb2Ti2O7 -Neutron Scattering Study-

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    Static and dynamical properties of the magnetic moment system of pyrochlore compound Tb2Ti2O7 with strong magnetic frustration, have been investigated down to the temperature T=0.4 K by neutron scattering on a single crystal sample. The scattering vector (Q)-dependence of the magnetic scattering intensity becomes appreciable with decreasing T at around 30 K, indicating the development of the magnetic correlation. From the observed energy profiles, the elastic, quasi elastic and inelastic components have been separately obtained. The quasi elastic component corresponds to the diffusive motion of the magnetic moments within the lowest states, which are formed of the lowest energy levels of Tb3+ ions. Magnetic correlation pattern which can roughly reproduce the Q-dependence of the scattering intensities of the elastic and quasi elastic component is discussed based on the trial calculations for clusters of 7 moments belonging to two corner-sharing tetrahedra. A possible origin of the glassy state, which develops at around 1.5 K with decreasing T is discussed.Comment: 10 pages, 12 figures, to be published in J. Phys. Soc. Jpn. 71(2002)No.2 59
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