Joint perceptual decision-making: a case study in explanatory pluralism.

Traditionally different approaches to the study of cognition have been viewed as competing explanatory frameworks. An alternative view, explanatory pluralism, regards different approaches to the study of cognition as complementary ways of studying the same phenomenon, at specific temporal and spatial scales, using appropriate methodological tools. Explanatory pluralism has been often described abstractly, but has rarely been applied to concrete cases. We present a case study of explanatory pluralism. We discuss three separate ways of studying the same phenomenon: a perceptual decision-making task (Bahrami et al., 2010), where pairs of subjects share information to jointly individuate an oddball stimulus among a set of distractors. Each approach analyzed the same corpus but targeted different units of analysis at different levels of description: decision-making at the behavioral level, confidence sharing at the linguistic level, and acoustic energy at the physical level. We discuss the utility of explanatory pluralism for describing this complex, multiscale phenomenon, show ways in which this case study sheds new light on the concept of pluralism, and highlight good practices to critically assess and complement approaches

Collective Dynamics of Random Polyampholytes

We consider the Langevin dynamics of a semi-dilute system of chains which are random polyampholytes of average monomer charge $q$ and with a fluctuations in this charge of the size $Q^{-1}$ and with freely floating counter-ions in the surrounding. We cast the dynamics into the functional integral formalism and average over the quenched charge distribution in order to compute the dynamic structure factor and the effective collective potential matrix. The results are given for small charge fluctuations. In the limit of finite $q$ we then find that the scattering approaches the limit of polyelectrolyte solutions.Comment: 13 pages including 6 figures, submitted J. Chem. Phy

Real-time Assessment of Right and Left Ventricular Volumes and Function in Children Using High Spatiotemporal Resolution Spiral bSSFP with Compressed Sensing

Background: Real-time (RT) assessment of ventricular volumes and function enables data acquisition during free-breathing. However, in children the requirement for high spatiotemporal resolution requires accelerated imaging techniques. In this study, we implemented a novel RT bSSFP spiral sequence reconstructed using Compressed Sensing (CS) and validated it against the breath-hold (BH) reference standard for assessment of ventricular volumes in children with heart disease. Methods: Data was acquired in 60 children. Qualitative image scoring and evaluation of ventricular volumes was performed by 3 clinical cardiac MR specialists. 30 cases were reassessed for intra-observer variability, and the other 30 cases for inter-observer variability. Results: Spiral RT images were of good quality, however qualitative scores reflected more residual artefact than standard BH images and slightly lower edge definition. Quantification of Left Ventricular (LV) and Right Ventricular (RV) metrics showed excellent correlation between the techniques with narrow limits of agreement. However, we observed small but statistically significant overestimation of LV end-diastolic volume, underestimation of LV end-systolic volume, as well as a small overestimation of RV stroke volume and ejection fraction using the RT imaging technique. No difference in inter-observer or intra-observer variability were observed between the BH and RT sequences. Conclusions: Real-time bSSFP imaging using spiral trajectories combined with a compressed sensing reconstruction is feasible. The main benefit is that it can be acquired during free breathing. However, another important secondary benefit is that a whole ventricular stack can be acquired in ~20 seconds, as opposed to ~6 minutes for standard BH imaging. Thus, this technique holds the potential to significantly shorten MR scan times in children

Weak Gravitational Lensing by a Sample of X-ray Luminous Clusters of Galaxies -- III. Serendipitous Weak Lensing Detections of Dark and Luminous Mass Concentrations

In the course of a weak gravitational lensing survey of 39 clusters of galaxies,covering a total sky area of ~1 square degree, we have serendipitously discovered mass concentrations in the fields of A1705 and A1722 which are most probably not associated with the main cluster target. By combining weak lensing information with two-color galaxy photometry in fields centered on our sample clusters, we identify a new cluster candidate at z~0.5 in the field of A1705. This cluster candidate also displays strong lensing in the form of a giant luminous arc. The new mass concentration in the field of A1722 also seems to be associated with an optically luminous cluster of galaxies at z~0.5, but in this case there is some evidence for additional structures along the line of sight that may contribute to the lensing signal. A third cluster, A959, has a dark sub-clump which shows interesting morphological evidence in the mass map for being associated with the main cluster. This is the first case where there is any significant evidence for a physical association between a dark sub-clump (discovered from weak lensing) and a normal cluster. Analysis of archival X-ray data shows that the three new mass concentrations are not firmly detected in X-rays and that they are X-ray underluminous.Comment: 14 pages, 10 figures, version accepted by ApJ. See http://www.nordita.dk/~dahle/paper3.ps.gz for a version with high-resolution figures and Fig.5 in colo