The impact of stroke: are people with aphasia different to those without?

Purpose. Stroke rehabilitation programmes aim to improve functional outcomes and quality of life. This study explored long-term outcomes in a cohort of people admitted to two acute stroke units with stroke. Comparisons were drawn between people with aphasia (PWA) and people without aphasia. Methods. People admitted to hospital with a first stroke were assessed at 2-weeks, 3-months and 6-months post-stroke. Measures included: the Barthel Index for Activities of Daily Living (ADL), the Frenchay Aphasia Screening Test, the General Health Questionnaire-12 for emotional well-being and the Stroke and Aphasia Quality of Life Scale-39g. Extended ADL and social support were also measured at 3 and 6 months, with the Frenchay Activities Index and the Social Support Survey, respectively. Results. Of 126 eligible participants, 96(76%) took part and 87(69%) were able to self-report. Self-report data are reported here. Although outcomes improved significantly across time, at 6 months people continued to experience substantial functional limitations (16% aphasic; 32% dependent on basic ADL); participation limitations (79% ≤30 on the FAI); high psychological distress (45%) and compromised quality of life (54% ≤4 on the SAQOL-39g). Levels of social support remained relatively stable. Though at 3-months post-stroke PWA were significantly more likely to experience high psychological distress (93% versus 50% for those without), across time, there were no significant differences between PWA and those without on psychological distress and also ADL and social support. There were, however, significant differences on extended ADL (F(1,68) = 7.80, p < 0.01) and quality of life (F(1,69) = 6.30, p < 0.05). Conclusion. PWA participated in fewer activities and reported worse quality of life after stroke than people without aphasia, even when their physical abilities, well-being and social support were comparable. Implications for clinical practice and future research are discussed

A Corpus-Based Analysis of the Language Used by Defendants of Homicide in Court

In this study we present the updated version of the Greek Corpus of Defendants’ Testimonies, GCDT and a series of new evaluations that have been carried out on the defendants’ speech. Using criteria, such as lexical richness, lexical density, part-of-speech frequencies, word and sentence length, we look for linguistic features which could characterize the stylometric profile of the defendants. We also present GCWT, a reference corpus that has been constructed similar to GCWT stylistic features. GCWT contains witnesses’ testimonies collected in the court

Model-Independent Test of General Relativity: An Extended post-Einsteinian Framework with Complete Polarization Content

We develop a model-independent test of General Relativity that allows for the constraint of the gravitational wave (GW) polarization content with GW detections of binary compact object inspirals. We first consider three modified gravity theories (Brans-Dicke theory, Rosen's theory and Lightman-Lee theory) and calculate the response function of ground-based detectors to gravitational waves in the inspiral phase. This allows us to see how additional polarizations predicted in these theories modify the General Relativistic prediction of the response function. We then consider general power-law modifications to the Hamiltonian and radiation-reaction force and study how these modify the time-domain and Fourier response function when all polarizations are present. From these general arguments and specific modified gravity examples, we infer an improved parameterized post-Einsteinian template family with complete polarization content. This family enhances General Relativity templates through the inclusion of new theory parameters, reducing to the former when these parameters acquire certain values, and recovering modified gravity predictions for other values, including all polarizations. We conclude by discussing detection strategies to constrain these new, polarization theory parameters by constructing certain null channels through the combination of output from multiple detectors.Comment: 20 pages, 1 figure, added erratum correcting some intermediate equation

Environmental variability and heavy metal concentrations from five lagoons in the Ionian Sea (Amvrakikos Gulf, W Greece)

Background: Coastal lagoons are ecosystems of major importance as they host a number of species tolerant to disturbances and they are highly productive. Therefore, these ecosystems should be protected to ensure stability and resilience. The lagoons of Amvrakikos Gulf form one of the most important lagoonal complexes in Greece. The optimal ecological status of these lagoons is crucial for the well-being of the biodiversity and the economic prosperity of the local communities. Thus, monitoring of the area is necessary to detect possible sources of disturbance and restore stability. New information: The environmental variables and heavy metals concentrations, from five lagoons of Amvrakikos Gulf were measured from seasonal samplings and compared to the findings of previous studies in the area, in order to check for possible sources of disturbance. The analysis, showed that i) the values of the abiotic parameters vary with time (season), space (lagoon) and with space over time; ii) the variability of the environmental factors and enrichment in certain elements is naturally induced and no source of contamination is detected in the lagoons

Psychometric properties of the Stroke and Aphasia Quality of Life Scale (SAQOL-39) in a generic stroke population

Background: We previously developed the Stroke and Aphasia Quality of Life scale (SAQOL-39) and tested it with people with chronic aphasia. A scale allowing comparisons of quality of life between people with versus without aphasia post-stroke would be of value to clinicians. Objectives: To evaluate the psychometrics of the SAQOL-39 in a generic stroke sample. Should this process result in a generic-stroke version of the scale (SAQOL-39g), a further aim is to compare the latter and the SAQOL-39 as tested in chronic aphasia. Design and subjects: Repeated measures psychometric study, evaluating internal consistency, test—retest reliability, construct validity and responsiveness to change. People admitted to hospital with a first stroke were assessed two weeks, three months and six months post stroke. Measures: SAQOL-39, National Institutes of Health Stroke Scale, Barthel, Frenchay Aphasia Screening Test, General Health Questionnaire-12 and Frenchay Activities Index. Results: Of 126 eligible participants, 96 (76%) participated and 87 (69%) were able to self-report and are presented here. Testing the SAQOL-39 in generic stroke resulted in the SAQOL-39g, which has the same items as the SAQOL-39 but three domains: physical, psychosocial, communication. The SAQOL-39g showed good internal consistency (α = 0.95 overall score, 0.92—0.95 domains), test—retest reliability (interclass correlation (ICC) = 0.96 overall, 0.92—0.98 domains), convergent (r = 0.36—0.70 overall, 0.47—0.78 domains) and discriminant validity (r = 0.26 overall, 0.03—0.40 domains). It differentiated people by stroke severity and visual analogue scale (VAS)-defined quality of life. Moderate changes (d = 0.35—0.49; standardized response mean (SRM) = 0.29—0.53) from two weeks to six months supported responsiveness. Conclusions: The SAQOL-39g demonstrated good reliability, validity and responsiveness to change. It can be used to evaluate quality of life in people with and without aphasia post stroke

Indoor fungal destroyers of wooden materials Their identification in present review

The wood-destroying fungi traditionally were separated from one another primarily on a basis of their sporocarp and/or strain morphology. Their diversity and simple macro- and micromorphology of fungal structures have been major obstacles for more rapid progress in this regard. However, over the past two decades, there has been substantial progress in our understanding of genetic variability within traditionally recognized morphospecies. In this study we have overviewed genetic variation and phylogeography of macrofungi, which are important destroyers of wooden materials indoor of buildings. Several morphologically defined species of these fungal destroyers (Coniophora puteana, C. olivacea, C. arida, Serpula himantioides) have been shown to actually encompass several genetically isolated lineages (cryptic species). The protective efficacy against cryptic species within traditionally recognized morphospecies through laboratory tests (EN 113) and field trials (EN 252) might be sufficient to better prognosis of decay development in wooden materials for hazard assessment and for proper conservation and management plans. © 2018 Statny Drevarsky Vyskumny Ustav.This work has been supported by grants from the Grant Agencies of the Ministry of Education, Science, Research and Sport of the Slovak Republic (VEGA No. 1/0286/17 and KEGA No. 025UMB-4/2017) and the Faculty of Sciences of the University of Ostrava, Czech Republic (SGS No. 16/PřF/2016).info:eu-repo/semantics/publishedVersio

Cognitive processes that indirectly affect olfactory dysfunction in Parkinson\u27s disease

Introduction Accurate early diagnosis of Parkinson\u27s disease is hampered by its long prodromal period and the variable manifestations of its motor symptoms. While olfactory dysfunction can occur before motor-symptom onset and serve as a non-disease-specific diagnostic aid, its underlying causes are incompletely understood. Methods Correlation analyses, univariate density estimates, ANOVA and regression evaluated relationships between scores on the Montreal Cognitive Assessment and Hopkins Verbal Learning Test and those on the University of Pennsylvania Smell Identification Test in 1280 Parkinson\u27s Progression Markers Initiative subjects placed into five diagnostic categories. Structural equation modeling identified cognitive measures having significant indirect effects on olfactory-function-test scores. Results Global cognition, verbal learning and memory, attention, delayed-recall, and visuospatial/executive function scores show weak-to-moderate, significant associations with olfactory-function-test scores. Associations are stronger in symptomatic than asymptomatic subjects having mutations in LRRK2, GBA or SNCA. Score distributions are nonuniform across diagnostic categories. Linear regression found that all cognitive measures except attention predicted olfactory-function-test scores. Three structural equation models assessing indirect effects of verbal learning/memory with either global cognition, visuospatial/executive function, or delayed-recall had a good statistical fit to the data. Only verbal learning/memory scores significantly help explain olfactory-function-test scores in all symptomatic diagnostic categories (−0.56 \u3c b \u3c −0.23, 0.001 \u3c P \u3c .005). Visuospatial/executive-function test scores help explain olfactory-function-test scores in both genetic Parkinson\u27s disease diagnostic categories (−0.25 \u3c b \u3c −0.17, 0.032 \u3c P \u3c .033). Conclusion Impaired verbal learning/memory and visuospatial/executive function contributes to lower performance on olfactory function tests in Parkinson\u27s disease. As both of these domains impact decision-making, decision-making in turn may impact olfactory assessment in Parkinson\u27s disease