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Action Initiation in the Human Dorsal Anterior Cingulate Cortex
The dorsal anterior cingulate cortex (dACC) has previously been implicated in processes that influence action initiation. In humans however, there has been little direct evidence connecting dACC to the temporal onset of actions. We studied reactive behavior in patients undergoing therapeutic bilateral cingulotomy to determine the immediate effects of dACC ablation on action initiation. In a simple reaction task, three patients were instructed to respond to a specific visual cue with the movement of a joystick. Within minutes of dACC ablation, the frequency of false starts increased, where movements occurred prior to presentation of the visual cue. In a decision making task with three separate patients, the ablation effect on action initiation persisted even when action selection was intact. These findings suggest that human dACC influences action initiation, apart from its role in action selection
Disordered GdUO with the cation antisite defects prepared by a combined mechanochemical−thermal method
The synthesis of the rhombohedral GdUO is reported via mechanochemical processing of stoichiometric GdO/UO mixtures and their subsequent annealing. Rietveld refinement of XRD data reveals that the as-prepared material exhibits a remarkable degree of cation antisite disorder and oxygen deficiency. The simulations of intensities of the selected XRD superlattice reflections are performed for limiting states of GdUO with its most extreme degrees of the cation antisite disorder. On the basis of the estimated bond lengths it can be stated that distorted geometry of structural units in the material is a consequence of its relatively large oxygen deficiency
On the Relative Sizes of Planets within Kepler Multiple-candidate Systems
We present a study of the relative sizes of planets within the multiple-candidate systems discovered with the Kepler mission. We have compared the size of each planet to the size of every other planet within a given planetary system after correcting the sample for detection and geometric biases. We find that for planet pairs for which one or both objects are approximately Neptune-sized or larger, the larger planet is most often the planet with the longer period. No such size-location correlation is seen for pairs of planets when both planets are smaller than Neptune. Specifically, if at least one planet in a planet pair has a radius of ≳ 3 R_⊕, 68% ± 6% of the planet pairs have the inner planet smaller than the outer planet, while no preferred sequential ordering of the planets is observed if both planets in a pair are smaller than ≾ 3 R_⊕
Transdermal delivery of gentamicin using dissolving microneedle arrays for potential treatment of neonatal sepsis
Local and global Fokker-Planck neoclassical calculations showing flow and bootstrap current modification in a pedestal
In transport barriers, particularly H-mode edge pedestals, radial scale
lengths can become comparable to the ion orbit width, causing neoclassical
physics to become radially nonlocal. In this work, the resulting changes to
neoclassical flow and current are examined both analytically and numerically.
Steep density gradients are considered, with scale lengths comparable to the
poloidal ion gyroradius, together with strong radial electric fields sufficient
to electrostatically confine the ions. Attention is restricted to relatively
weak ion temperature gradients (but permitting arbitrary electron temperature
gradients), since in this limit a delta-f (small departures from a Maxwellian
distribution) rather than full-f approach is justified. This assumption is in
fact consistent with measured inter-ELM H-Mode edge pedestal density and ion
temperature profiles in many present experiments, and is expected to be
increasingly valid in future lower collisionality experiments. In the numerical
analysis, the distribution function and Rosenbluth potentials are solved for
simultaneously, allowing use of the exact field term in the linearized
Fokker-Planck collision operator. In the pedestal, the parallel and poloidal
flows are found to deviate strongly from the best available conventional
neoclassical prediction, with large poloidal variation of a different form than
in the local theory. These predicted effects may be observable experimentally.
In the local limit, the Sauter bootstrap current formulae appear accurate at
low collisionality, but they can overestimate the bootstrap current near the
plateau regime. In the pedestal ordering, ion contributions to the bootstrap
and Pfirsch-Schluter currents are also modified
A First Comparison of Kepler Planet Candidates in Single and Multiple Systems
In this letter we present an overview of the rich population of systems with
multiple candidate transiting planets found in the first four months of Kepler
data. The census of multiples includes 115 targets that show 2 candidate
planets, 45 with 3, 8 with 4, and 1 each with 5 and 6, for a total of 170
systems with 408 candidates. When compared to the 827 systems with only one
candidate, the multiples account for 17 percent of the total number of systems,
and a third of all the planet candidates. We compare the characteristics of
candidates found in multiples with those found in singles. False positives due
to eclipsing binaries are much less common for the multiples, as expected.
Singles and multiples are both dominated by planets smaller than Neptune; 69
+2/-3 percent for singles and 86 +2/-5 percent for multiples. This result, that
systems with multiple transiting planets are less likely to include a
transiting giant planet, suggests that close-in giant planets tend to disrupt
the orbital inclinations of small planets in flat systems, or maybe even to
prevent the formation of such systems in the first place.Comment: 13 pages, 13 figures, submitted to ApJ Letter
Modeling Kepler transit light curves as false positives: Rejection of blend scenarios for Kepler-9, and validation of Kepler-9d, a super-Earth-size planet in a multiple system
Light curves from the Kepler Mission contain valuable information on the
nature of the phenomena producing the transit-like signals. To assist in
exploring the possibility that they are due to an astrophysical false positive,
we describe a procedure (BLENDER) to model the photometry in terms of a "blend"
rather than a planet orbiting a star. A blend may consist of a background or
foreground eclipsing binary (or star-planet pair) whose eclipses are attenuated
by the light of the candidate and possibly other stars within the photometric
aperture. We apply BLENDER to the case of Kepler-9, a target harboring two
previously confirmed Saturn-size planets (Kepler-9b and Kepler-9c) showing
transit timing variations, and an additional shallower signal with a 1.59-day
period suggesting the presence of a super-Earth-size planet. Using BLENDER
together with constraints from other follow-up observations we are able to rule
out all blends for the two deeper signals, and provide independent validation
of their planetary nature. For the shallower signal we rule out a large
fraction of the false positives that might mimic the transits. The false alarm
rate for remaining blends depends in part (and inversely) on the unknown
frequency of small-size planets. Based on several realistic estimates of this
frequency we conclude with very high confidence that this small signal is due
to a super-Earth-size planet (Kepler-9d) in a multiple system, rather than a
false positive. The radius is determined to be 1.64 (+0.19/-0.14) R(Earth), and
current spectroscopic observations are as yet insufficient to establish its
mass.Comment: 20 pages in emulateapj format, including 8 tables and 16 figures. To
appear in ApJ, 1 January 2010. Accepted versio
Observation of Stratospheric Ozone Depletion associated with Delta II Rocket Emissions
Ozone, chlorine monoxide, methane, and submicron particulate concentrations were measured in the stratospheric plume wake of a Delta II rocket powered by a combination of solid (NH4ClO4/Al) and liquid (LOX/kerosene) propulsion systems. We apply a simple kinetics model describing the main features of gas-phase chlorine reactions in solid propellant exhaust plumes to derive the abundance of total reactive chlorine in the plume and estimate the associated cumulative ozone loss. Measured ozone loss during two plume encounters (12 and 39 minutes after launch) exceeded the estimate by about a factor of about two. Insofar as only the most significant gas-phase chlorine reactions are included in the calculation, these results suggest that additional plume wake chemical processes or emissions other than reactive chlorine from the Delta II propulsion system affect ozone levels in the plume
Planetary Candidates Observed by Kepler IV: Planet Sample From Q1-Q8 (22 Months)
We provide updates to the Kepler planet candidate sample based upon nearly
two years of high-precision photometry (i.e., Q1-Q8). From an initial list of
nearly 13,400 Threshold Crossing Events (TCEs), 480 new host stars are
identified from their flux time series as consistent with hosting transiting
planets. Potential transit signals are subjected to further analysis using the
pixel-level data, which allows background eclipsing binaries to be identified
through small image position shifts during transit. We also re-evaluate Kepler
Objects of Interest (KOI) 1-1609, which were identified early in the mission,
using substantially more data to test for background false positives and to
find additional multiple systems. Combining the new and previous KOI samples,
we provide updated parameters for 2,738 Kepler planet candidates distributed
across 2,017 host stars. From the combined Kepler planet candidates, 472 are
new from the Q1-Q8 data examined in this study. The new Kepler planet
candidates represent ~40% of the sample with Rp~1 Rearth and represent ~40% of
the low equilibrium temperature (Teq<300 K) sample. We review the known biases
in the current sample of Kepler planet candidates relevant to evaluating planet
population statistics with the current Kepler planet candidate sample.Comment: 12 pages, 8 figures, Accepted ApJ Supplemen
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