Effects of drip irrigation on the yield of strawberry plants grown under arable conditions

ArticleThe study investigated the effects of drip irrigation on the yield of ‘Honeoye’ strawberry plants for commercial purposes grown under arable conditions throughout the harvest season. The plants were irrigated at irregular intervals depending on natural precipitation. Crop yields and fruit parameters (diameter, length, individual weight, count per plant) were compared on several harvest dates. Statistical analysis has shown that irrigation has a significant impact on yield and fruit parameters. The irrigated plants yielded more strawberries, which also had a larger diameter, length, and individual weight

Association between body condition and production parameters of dairy cows in the experiment with use of BCS camera

Dairy production effectiveness in the farm depends on many technical, technological and biological factors. State of the dairy cow condition constitutes one of the most important element in the assessment of dairy herd and production indices. Including access to modern technical solution to assess body condition of dairy cows, i.e. BCS camera, some results of observation in the herd with 362 cows were collected to find any relationship between BCS index and milk yield per cow including 5 lactation groups and cows differed in age as well as four seasons. Basing on data collected in the period of 11 months it was found that cows with the BCS index lower than 2.9 showed the highest daily milk production. Increase in BCS index was associated with decrease in amount of produced milk per day. The statistical analysis showed significant effect of lactation period, age of animals and season on BCS results in the considered dairy cow production cycle

Weight loss randomized intervention trials in female cancer survivors

Purpos

Estrogen and progesterone-related gene variants and colorectal cancer risk in women

<p>Abstract</p> <p>Background</p> <p>Observational studies and randomized trials have suggested that estrogens and/or progesterone may lower the risk for colorectal cancer. Inherited variation in the sex-hormone genes may be one mechanism by which sex hormones affect colorectal cancer, although data are limited.</p> <p>Method</p> <p>We conducted a comprehensive evaluation of single nucleotide polymorphisms (SNPs) in genes encoding 3 hormone receptors (<it>ESR1, ESR2, PGR</it>) and 5 hormone synthesizers (<it>CYP19A1 and CYP17A1, HSD17B1, HSD17B2, HSD17B4</it>) among 427 women with incident colorectal cancer and 871 matched controls who were Caucasians of European ancestry from 93676 postmenopausal women enrolled in the Women's Health Initiative Observational cohort. A total of 242 haplotype-tagging and functional SNPs in the 8 genes were included for analysis. Unconditional logistic regression with adjustment for age and hysterectomy status was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).</p> <p>Results</p> <p>We observed a weak association between the <it>CYP17A1 </it>rs17724534 SNP and colorectal cancer risk (OR per risk allele (A) = 1.39, 95% CI = 1.09-1.78, corrected p-value = 0.07). In addition, a suggestive interaction between rs17724534 and rs10883782 in 2 discrete LD blocks of <it>CYP17A1 </it>was observed in relation to colorectal cancer (empirical p value = 0.04). Moreover, one haplotype block of <it>CYP19A1 </it>was associated with colorectal cancer (corrected global p value = 0.02), which likely reflected the association with the tagging SNP, rs1902584, in the block.</p> <p>Conclusion</p> <p>Our findings offer some support for a suggestive association of <it>CYP17A1 </it>and <it>CYP19A1 </it>variants with colorectal cancer risk.</p

Colorectal cancer in relation to postmenopausal estrogen and estrogen plus progestin in the Women’s Health Initiative clinical trial and observational study

Background: Colorectal cancer incidence was reduced among women assigned to active treatment in the Women’s Health Initiative (WHI) estrogen plus progestin randomized trial, but the interpretation was obscured by an associated later stage of diagnosis. In contrast the estrogen-alone trial showed no incidence reduction or differential stage at diagnosis. Here, data from the WHI observational study are considered, in conjunction with colorectal cancer mortality data from the hormone therapy trials, in an attempt to clarify postmenopausal hormone therapy effects. Participants and Methods: Postmenopausal women aged 50-79 at WHI enrollment. Estrogen-alone analyses include 21,552 and 10,739 women who were post-hysterectomy from the observational study and clinical trial respectively. Estrogen plus progestin analyses include 32,084 and 16,608 observational study and clinical trial women with uterus. Colorectal cancers were verified by central medical and pathology report review. Results: Hazard ratios (95% confidence intervals) from the WHI observational study were 0.80 (0.53 to 1.20) for estrogen and 1.15 (0.74 to 1.79) for estrogen plus progestin, with respectively 168 and 175 women diagnosed with colorectal cancer. Delayed diagnosis with estrogen plus progestin is not evident in the observational study. No protective effect on colorectal cancer mortality in the estrogen plus progestin trial is seen over an 8-year intervention and follow-up period. Conclusion: Hazard ratio patterns in the WHI clinical trial and observational study do not provide strong evidence of a clinically important colorectal cancer benefit with either estrogen-alone or estrogen plus progestin over 7-8 years of treatment and follow-up

The Aromatase Gene (CYP19A1) Variants and Circulating Hepatocyte Growth Factor in Postmenopausal Women

Background: Estrogen and androgen have been linked to the regulation of circulating hepatocyte growth factor (HGF), an adipose tissue-derived cytokine. It is possible that the CYP19A1 gene which alters sex hormones production may influence HGF levels. We examined the association between the CYP19A1 gene variants and plasma HGF concentrations. Design We evaluated 45 common and putative functional variants of CYP19A1 and circulating levels of HGF among 260 postmenopausal women who later developed colorectal cancer from the Women's Health Initiative Observational Cohort. As the distribution of HGF levels was highly skewed, we transformed HGF concentrations for all women into a log-, ranked-, or normal score-scale value. Multiple linear regression with adjustment for age was used to evaluate the associations. Results: We observed an association between the rs7172156, rs1008805, rs6493494, rs749292, and rs11636639 variants and HGF levels in ranked and normal score scales (corrected p values ≤0.02), although the association of these 5 SNPs with log-scale HGF was not significant (corrected p values ≥0.16). The associations remained unchanged after additional adjustment for hormone therapy use and estradiol levels. These 5 SNPs, which were in linkage disequilibrium (pairwise D′≥97%, r2≥56%), constituted a block with 2 common haplotypes accounting for 82% frequency. The most common haplotype, TCCCA, was associated with lower ranked- or normal score-transformed HGF levels (corrected p values ≤0.001), whereas the second most common haplotype, CTTCA, was associated with higher ranked- or normal score-transformed HGF levels (corrected p values ≤0.02). Conclusion: Our findings of a potential association between the CYP19A1 variants and circulating HGF levels warrant confirmation in studies with larger sample size

Low mass loss rates in O-type stars: Spectral signatures of dense clumps in the wind of two Galactic O4 stars

We have analyzed the far-UV spectrum of two Galactic O4 stars, the O4If+ supergiant HD190429A and the O4V((f)) dwarf HD96715, using archival FUSE and IUE data. We have conducted a quantitative analysis based on the two NLTE model atmosphere and wind codes, TLUSTY and CMFGEN. We have derived the stellar and wind parameters and the surface composition of the two stars. The surface of HD190429A has a composition typical of an evolved O supergiant (N-rich, C and O-poor), while HD96715 exhibits surface N enhancement similar to the enrichment found in SMC O dwarfs and attributed to rotationally-induced mixing. We find that homogeneous wind models could not match the observed profile of O V1371 and require very low phosphorus abundance to fit the P V1118-1128 resonance lines. However, we are able to match the O V and P V lines using clumped wind models. We find that N IV1718 is also sensitive to wind clumping. For both stars, we have calculated clumped wind models that match well all these lines from different species and that remain consistent with Halpha data. These fits therefore provide a coherent and thus much stronger evidence of wind clumping in O stars than earlier claims. We find that the wind of these two stars is highly clumped, as expressed by very small volume filling factors, namely f=0.04 for HD190429A and f=0.02 for HD96715. In agreement with our analysis of SMC stars, clumping starts deep in the wind, just above the sonic point. The most crucial consequence of our analysis is that the mass loss rates of O stars need to be revised downward significantly, by a factor of 3 and more. Accounting for wind clumping is essential when determining the wind properties of O stars. Our study therefore calls for a fundamental revision in our understanding of mass loss and of O-type star winds. (abridged)Comment: To appear in Astronomy & Astrophysics; 16 pages; accepted version after minor revisio