569 research outputs found
Interference effects in electronic transport through metallic single-wall carbon nanotubes
In a recent paper Liang {\it et al.} [Nature {\bf 411}, 665 (2001)] showed
experimentally, that metallic nanotubes, strongly coupled to external
electrodes, may act as coherent molecular waveguides for electronic transport.
The experimental results were supported by theoretical analysis based on the
scattering matrix approach. In this paper we analyze theoretically this problem
using a real-space approach, which makes it possible to control quality of
interface contacts. Electronic structure of the nanotube is taken into account
within the tight-binding model. External electrodes and the central part
(sample) are assumed to be made of carbon nanotubes, while the contacts between
electrodes and the sample are modeled by appropriate on-site (diagonal) and
hopping (off-diagonal) parameters. Conductance is calculated by the Green
function technique combined with the Landauer formalism. In the plots
displaying conductance {\it vs.} bias and gate voltages, we have found typical
diamond structure patterns, similar to those observed experimentally. In
certain cases, however, we have found new features in the patterns, like a
double-diamond sub-structure.Comment: 15 pages, 4 figures. To apear in Phys. Rev.
Spintronic transport and Kondo effect in quantum dots
We investigate the spin-dependent transport properties of quantum-dot based
structures where Kondo correlations dominate the electronic dynamics. The
coupling to ferromagnetic leads with parallel magnetizations is known to give
rise to nontrivial effects in the local density of states of a single quantum
dot. We show that this influence strongly depends on whether charge
fluctuations are present or absent in the dot. This result is confirmed with
numerical renormalization group calculations and perturbation theory in the
on-site interaction. In the Fermi-liquid fixed point, we determine the
correlations of the electric current at zero temperature (shot noise) and
demonstrate that the Fano factor is suppressed below the Poissonian limit for
the symmetric point of the Anderson Hamiltonian even for nonzero lead
magnetizations. We discuss possible avenues of future research in this field:
coupling to the low energy excitations of the ferromagnets (magnons), extension
to double quantum dot systems with interdot antiferromagnetic interaction and
effect of spin-polarized currents on higher symmetry Kondo states such as
SU(4).Comment: 11 pages, 5 figures. Proceedings of the 3rd Intl. Conf. on Physics
and Applications of Spin-Related Phenomena in Semiconductors, Santa Barbara,
200
Spin-Polarized Transprot through Double Quantum Dots
We investigate spin-polarized transport phenomena through double quantum dots
coupled to ferromagnetic leads in series. By means of the slave-boson
mean-field approximation, we calculate the conductance in the Kondo regime for
two different configurations of the leads: spin-polarization of two
ferromagnetic leads is parallel or anti-parallel. It is found that transport
shows some remarkable properties depending on the tunneling strength between
two dots. These properties are explained in terms of the Kondo resonances in
the local density of states.Comment: 8 pages, 11 figure
Crossover from Kondo assisted suppression to co-tunneling enhancement of tunneling magnetoresistance via ferromagnetic nanodots in MgO tunnel barriers
Recently, it has been shown that magnetic tunnel junctions with thin MgO
tunnel barriers exhibit extraordinarily high tunneling magnetoresistance (TMR)
values at room temperature1, 2. However, the physics of spin dependent
tunneling through MgO barriers is only beginning to be unravelled. Using planar
magnetic tunnel junctions in which ultra-thin layers of magnetic metals are
deposited in the middle of a MgO tunnel barrier here we demonstrate that the
TMR is strongly modified when these layers are discontinuous and composed of
small pancake shaped nanodots. At low temperatures, in the Coulomb blockade
regime, for layers less than ~1 nm thick, the conductance of the junction is
increased at low bias consistent with Kondo assisted tunneling. In the same
regime we observe a suppression of the TMR. For slightly thicker layers, and
correspondingly larger nanodots, the TMR is enhanced at low bias, consistent
with co-tunneling.Comment: Nano Letters (in press
Action research in physical education: focusing beyond myself through cooperative learning
This paper reports on the pedagogical changes that I experienced as a teacher engaged in an action research project in which I designed and implemented an indirect, developmentally appropriate and childâcentred approach to my teaching. There have been repeated calls to expunge â or at least rationalise â the use of traditional, teacherâled practice in physical education. Yet despite the advocacy of many leading academics there is little evidence that such a change of approach is occurring. In my role as teacherâasâresearcher I sought to implement a new pedagogical approach, in the form of cooperative learning, and bring about a positive change in the form of enhanced pupil learning. Data collection included a reflective journal, postâteaching reflective analysis, pupil questionnaires, student interviews, document analysis, and nonâparticipant observations. The research team analysed the data using inductive analysis and constant comparison. Six themes emerged from the data: teaching and learning, reflections on cooperation, performance, time, teacher change, and social interaction. The paper argues that cooperative learning allowed me to place social and academic learning goals on an even footing, which in turn placed a focus on pupilsâ understanding and improvement of skills in athletics alongside their interpersonal development
Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes
Objective: To identify an appropriate cell source for the generation of meniscus substitutes, among those which would be available by arthroscopy of injured knee joints. Methods: Human inner meniscus cells, fat pad cells (FPC), synovial membrane cells (SMC) and articular chondrocytes (AC) were expanded with or without specific growth factors (Transforming growth factor-betal, Fibroblast growth factor-2 and Plate let-derived growth factor bb, TFP) and then induced to form three-dimensional cartilaginous tissues in pellet cultures, or using a hyaluronan-based scaffold (Hyaff(R)-11), in culture or in nude mice. Human native menisci were assessed as reference. Results: Cell expansion with TFP enhanced glycosaminoglycan (GAG) deposition by all cell types (up to 4.1-fold) and messenger RNA expression of collagen type II by FPC and SMC (up to 472-fold) following pellet culture. In all models, tissues generated by AC contained the highest fractions of GAG (up to 1.9 were positively stained for collagen type II (specific of the inner avascular region of meniscus), type IV (mainly present in the outer vascularized region of meniscus) and types I, III and VI (common to both meniscus regions). Instead, inner meniscus, FPC and SMC developed tissues containing negligible GAG and no detectable collagen type II protein. Tissues generated by AC remained biochemically and phenotypically stable upon ectopic implantation. Conclusions: Under our experimental conditions, only AC generated tissues containing relevant amounts of GAG and with cell phenotypes compatible with those of the inner and outer meniscus regions. Instead, the other investigated cell sources formed tissues resembling only the outer region of meniscus. It remains to be determined whether grafts based on AC will have the ability to reach the complex structural and functional organization typical of meniscus tissue. (C) 2006 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights rese
Magnetic Field Dependence of Macroscopic Quantum Tunneling and Coherence of Ferromagnetic Particle
We calculate the quantum tunneling rate of a ferromagnetic particle of diameter in a magnetic field of arbitrary angle. We consider the
magnetocrystalline anisotropy with the biaxial symmetry and that with the
tetragonal symmetry. Using the spin-coherent-state path integral, we obtain
approximate analytic formulas of the tunneling rates in the small -limit for the magnetic field normal to the easy axis (), for the field opposite to the initial easy axis (),
and for the field at an angle between these two orientations (). In addition, we obtain numerically the tunneling rates for
the biaxial symmetry in the full range of the angle of the magnetic
field (), for the values of \epsilon =0.01 and
0.001.Comment: 25 pages of text (RevTex) and 4 figures (PostScript files), to be
published in Phys. Rev.
Spintronics: Fundamentals and applications
Spintronics, or spin electronics, involves the study of active control and
manipulation of spin degrees of freedom in solid-state systems. This article
reviews the current status of this subject, including both recent advances and
well-established results. The primary focus is on the basic physical principles
underlying the generation of carrier spin polarization, spin dynamics, and
spin-polarized transport in semiconductors and metals. Spin transport differs
from charge transport in that spin is a nonconserved quantity in solids due to
spin-orbit and hyperfine coupling. The authors discuss in detail spin
decoherence mechanisms in metals and semiconductors. Various theories of spin
injection and spin-polarized transport are applied to hybrid structures
relevant to spin-based devices and fundamental studies of materials properties.
Experimental work is reviewed with the emphasis on projected applications, in
which external electric and magnetic fields and illumination by light will be
used to control spin and charge dynamics to create new functionalities not
feasible or ineffective with conventional electronics.Comment: invited review, 36 figures, 900+ references; minor stylistic changes
from the published versio
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Establishment of an in vivo small animal model of human tumor and human immune system interaction would enable preclinical investigations into the mechanisms underlying cancer immunotherapy. To this end, nonobese diabetic (NOD).Cg- PrkdcscidIL2rgtm1Wjl/Sz (null; NSG) mice were transplanted with human (h)CD34+ hematopoietic progenitor and stem cells, which leads to the development of human hematopoietic and immune systems [humanized NSG (HuNSG)]. HuNSG mice received human leukocyte antigen partially matched tumor implants from patient-derived xenografts [PDX; non-small cell lung cancer (NSCLC), sarcoma, bladder cancer, and triple-negative breast cancer (TNBC)] or from a TNBC cell line-derived xenograft (CDX). Tumor growth curves were similar in HuNSG compared with nonhuman immune-engrafted NSG mice. Treatment with pembrolizumab, which targets programmed cell death protein 1, produced significant growth inhibition in both CDX and PDX tumors in HuNSG but not in NSG mice. Finally, inhibition of tumor growth was dependent on hCD8+ T cells, as demonstrated by antibody-mediated depletion. Thus, tumor-bearing HuNSG mice may represent an important, new model for preclinical immunotherapy research.
FASEB J 2018 Mar; 32(3):1537-1549
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