Analysis of physical-chemical processes governing SSME internal fluid flows

The efforts to adapt CHAM's computational fluid dynamics code, PHOENICS, to the analysis of flow within the high pressure fuel turbopump (HPFTP) aft-platform seal cavity of the SSME are summarized. In particular, the special purpose PHOENICS satellite and ground station specifically formulated for this application are listed and described, and the preliminary results of the first part two-dimensional analyses are presented and discussed. Planned three-dimensional analyses are also briefly outlined. To further understand the mixing and combustion processes in the SSME fuelside preburners, a single oxygen-hydrogen jet element was investigated

Toward a Complete Metrological Solution for the Mirrors for the Constellation-X Spectroscopy X-ray Telescope

We present an overview update of the metrological approach to be employed for the segmented mirror fabrication for Constellation-X spectroscopy x-ray telescope. We compare results achieved to date with mission requirements. This is discussed in terms of inherent capability versus in-practice capability

Influence of Humidity on Ultraviolet Injury

High humidity enhances the injurious effect of ultraviolet radiation. This was demonstrated in experiments in which hairless mice were irradiated with Westinghouse FS-40-T-12 sunlamps while maintained in an environmental chamber allowing controlled conditions of relative humidity and temperature. Hairless mice given 10 MED (minimal erythemal dose) while maintained at 80% relative humidity had markedly greater exfoliation, crusting, and erosion of skin than did mice maintained at 5% and 10% relative humidity. Animals kept at 50% humidity had damage intermediate to those kept at high and low humidity. These morphologic observations were confirmed histologically.Additionally, water immersion enhances ultraviolet injury. Animals immersed in water for 6 hr prior to irradiation with 3 MED had more damage than animals irradiated but not immersed. Similarly, albino rabbits irradiated with 300 nm radiation from a xenon arc grating monochrometer had lower erythemal energy requirements on that part of their skin that had been hydrated with wet packs compared to nonhydrated skin

Influence of Source Credibility on Agricultural Water Use Communication

As the agriculture industry strives to communicate with the public about its role in protecting natural resources such as water, it struggles to provide messages from sources the public trusts. The purpose of this quasi-experimental study explored public perception of agricultural water use and how perception was influenced by a video message delivered from four different sources including 1) an environmental scientist from the Nature Conservancy, 2) a farmer, 3) a regulator from a Florida water management district, and 4) a water scientist from the University of Florida. The findings revealed that overall the general public had a positive view of how the agriculture industry used water, regardless of message source. Differences between groups were evident when message source expertise and trustworthiness was dependent on domain area. Results indicated the respondents receiving the Nature Conservancy video treatment exhibited a significantly higher level of agreement with negatively framed items related to agriculture’s relationship with the natural environment than the respondents receiving the farmer video treatment. Based on the findings from this study, agricultural communicators should consider the trustworthiness and perceived expertise of sources, such as representatives from regulatory agencies, educational institutions, members of the agriculture sector, or environmental organizations, when developing messages about water use targeted at the general public

Eddy stirring and horizontal diffusivity from Argo float observations : geographic and depth variability

Author Posting. © American Geophysical Union, 2015. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Geophysical Research Letters 42 (2015): 3989–3997, doi:10.1002/2015GL063827.Stirring along isopycnals is a significant factor in determining the distribution of tracers within the ocean. Salinity anomalies on density surfaces from Argo float profiles are used to investigate horizontal stirring and estimate eddy mixing lengths. Eddy mixing length and velocity fluctuations from the ECCO2 global state estimate are used to estimate horizontal diffusivity at a 300 km scale in the upper 2000 m with near-global coverage. Diffusivity varies by over two orders of magnitude with latitude, longitude, and depth. In all basins, diffusivity is elevated in zonal bands corresponding to strong current regions, including western boundary current extension regions, the Antarctic Circumpolar Current, and equatorial current systems. The estimated mixing lengths and diffusivities provide an observationally based data set that can be used to test and constrain predictions and parameterizations of eddy stirring.This work was supported by the National Science Foundation under grants OCE-13-55668 and OCE-95-21468 and the Office of Naval Research under grants N00014-12-1-0336 and N00014-13-1-0484.2015-11-2

Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus.

Gliotoxin is an epipolythiodioxopiperazine (ETP) class toxin, contains a disulfide bridge that mediates its toxic effects via redox cycling and is produced by the opportunistic fungal pathogen Aspergillus fumigatus Self-resistance against gliotoxin is effected by the gliotoxin oxidase GliT, and attenuation of gliotoxin biosynthesis is catalysed by gliotoxin S-methyltransferase GtmA. Here we describe the X-ray crystal structures of GtmA-apo (1.66 Å), GtmA complexed to S-adenosylhomocysteine (1.33 Å) and GtmA complexed to S-adenosylmethionine (2.28 Å), providing mechanistic insights into this important biotransformation. We further reveal that simultaneous elimination of the ability of A. fumigatus to dissipate highly reactive dithiol gliotoxin, via deletion of GliT and GtmA, results in the most significant hypersensitivity to exogenous gliotoxin observed to date. Indeed, quantitative proteomic analysis of ΔgliT::ΔgtmA reveals an uncontrolled over-activation of the gli-cluster upon gliotoxin exposure. The data presented herein reveal, for the first time, the extreme risk associated with intracellular dithiol gliotoxin biosynthesis-in the absence of an efficient dismutation capacity. Significantly, a previously concealed protective role for GtmA and functionality of ETP bis-thiomethylation as an ancestral protection strategy against dithiol compounds is now evident

The radius and mass of the subgiant star bet Hyi from interferometry and asteroseismology

We have used the Sydney University Stellar Interferometer (SUSI) to measure the angular diameter of beta Hydri. This star is a nearby G2 subgiant whose mean density was recently measured with high precision using asteroseismology. We determine the radius and effective temperature of the star to be 1.814+/-0.017 R_sun (0.9%) and 5872+/-44 K (0.7%) respectively. By combining this value with the mean density, as estimated from asteroseismology, we make a direct estimate of the stellar mass. We find a value of 1.07+/-0.03 M_sun (2.8%), which agrees with published estimates based on fitting in the H-R diagram, but has much higher precision. These results place valuable constraints on theoretical models of beta Hyi and its oscillation frequencies.Comment: 3 figures, 3 tables, to appear in MNRAS Letter

Jet photoproduction and the structure of the photon

Various jet observables in photoproduction are studied and compared to data from HERA. The feasibility of using a dijet sample for constraining the parton distributions in the photon is then studied. For the current data the experimental and theoretical uncertainties are comparable to the variation due to changing the photon parton distribution set.Comment: 20 pages including 11 figures. Latex using revtex and psfig macros. Several references added. Submitted to Phys. Rev.