458 research outputs found
Yleissotatieteellisiä huomioita
Artikkelin peruskysymys on "Miten saataisiin sodankäynti vapautetuksi asemasodan jäykkyydestä, miten päästäisiin taas suorittamaan nopeita ratkaisevia liikkeitä, joilla vihollisen tahto voidaan nujertaa tarvitsematta valmistautua pitkäaikaiseen sotaan, jonka kaikille aloille ulottuvat tavattoman raskaat seuraukset ovat nykypolvelle niin ilmeisiä?"Kirjoittajan mukaan vallalla on maailmanlaajuisesti kaksi suuntausta, koneellistettujen joukkojen käyttö tai ilmasotadoktriini, joilla sodista tulisi lyhyitä.Artikkelissa esitetään, että jalkaväen itsensä on saatava aikaan liikkuva sodankäynti, jolla pystytään raivaaman tie puolustajan läpi. Artikkelissa tarkastellaan sveitsiläisen eversti Sondereggerin teosta "Infanterieangriff und strategische Operation", jonka todetaan vaikuttaneen artikkelin sisältöön ja sen periaatteita käsitelläänkin melko seikkaperäisesti. Tarkastelussa on muun muassa mukana Ruotsissa 1930-luvun alkupuolella toteutetut organisaatiokokeilut pataljoonan, divisioonan ja prikaatin puitteissa. Lisäksi tarkastellaan englantialaisia ja amerikkalaisia sekä saksalaisia periaatteita. Artikkelissa esitetään muun muassa pataljoonan organisaatio esimerkkinä kevyen jalkaväen organisaationa. Kirjoittajan mukaan jalkaväen kehittämisessä on havaittavissa kolme päävirtausta: 1.kaaritulen lisääminen, vaikkapa automaattisen laakatulen kustannuksella, 2. äärimmäisen vahvan automaattisen laakatulen kehittäminen hyökkäävän jalkaväen etulinjasta ja 3. jalkaväen moottoroiminen ja panssaroiminen, sekä jalkamiehen kantamuksen keventäminen lähitaistelua varten
Efficacy of rabies vaccines in dogs and cats and protection in a mouse model against European bat lyssavirus type 2
Background: Rabies is preventable by pre- and/or post-exposure prophylaxis consisting of series of rabies vaccinations and in some cases the use of immunoglobulins. The success of vaccination can be estimated either by measuring virus neutralising antibodies or by challenge experiment. Vaccines based on rabies virus offer cross-protection against other lyssaviruses closely related to rabies virus. The aim was to assess the success of rabies vaccination measured by the antibody response in dogs (n = 10,071) and cats (n = 722), as well as to investigate the factors influencing the response to vaccination when animals failed to reach a rabies antibody titre of ≥ 0.5 IU/ml. Another aim was to assess the level of protection afforded by a commercial veterinary rabies vaccine against intracerebral challenge in mice with European bat lyssavirus type 2 (EBLV-2) and classical rabies virus (RABV), and to compare this with the protection offered by a vaccine for humans. Results: A significantly higher proportion of dogs (10.7%, 95% confidence interval CI 10.1–11.3) than cats (3.5%; 95% CI 2.3–5.0) had a vaccination antibody titre of 60 cm or larger resulted in a higher risk of failing to reach an antibody level of at least 0.5 IU/ml. When challenged with EBLV-2 and RABV, 80 and 100% of mice vaccinated with the veterinary rabies vaccine survived, respectively. When mice were vaccinated with the human rabies vaccine and challenged with EBLV-2, 75–80% survived, depending on the booster. All vaccinated mice developed sufficient to high titres of virus-neutralising antibodies (VNA) against RABV 21–22 days post-vaccination, ranging from 0.5 to 128 IU/ml. However, there was significant difference between antibody titres after vaccinating once in comparison to vaccinating twice (P < 0.05). Conclusions: There was a significant difference between dogs and cats in their ability to reach a post vaccination antibody titre of ≥ 0.5 IU/ml. Mice vaccinated with RABV-based rabies vaccines were partly cross-protected against EBLV-2, but there was no clear correlation between VNA titres and cross-protection against EBLV-2. Measurement of the RABV VNA titre can only be seen as a partial tool to estimate the cross-protection against other lyssaviruses. Booster vaccination is recommended for dogs and cats if exposed to infected bats
Fast computation of the geoelectric field using the method of elementary current systems and planar Earth models
International audienceThe method of spherical elementary current systems provides an accurate modelling of the horizontal component of the geomagnetic variation field. The interpolated magnetic field is used as input to calculate the horizontal geoelectric field. We use planar layered (1-D) models of the Earth's conductivity, and assume that the electric field is related to the local magnetic field by the plane wave surface impedance. There are locations in which the conductivity structure can be approximated by a 1-D model, as demonstrated with the measurements of the Baltic Electromagnetic Array Research project. To calculate geomagnetically induced currents (GIC), we need the spatially integrated electric field typically in a length scale of 100km. We show that then the spatial variation of the electric field can be neglected if we use the measured or interpolated magnetic field at the site of interest. In other words, even the simple plane wave model is fairly accurate for GIC purposes. Investigating GIC in the Finnish high-voltage power system and in the natural gas pipeline, we find a good agreement between modelled and measured values, with relative errors less than 30% for large GIC values. Key words. Geomagnetism and paleomagnetism (geomagnetic induction; rapid time variations) ? Ionosphere (electric field and currents
Real-time and post-processed georeferencing for hyperpspectral drone remote sensing
The use of drones and photogrammetric technologies are increasing rapidly in different applications. Currently, drone processing workflow is in most cases based on sequential image acquisition and post-processing, but there are great interests towards real-time solutions. Fast and reliable real-time drone data processing can benefit, for instance, environmental monitoring tasks in precision agriculture and in forest. Recent developments in miniaturized and low-cost inertial measurement systems and GNSS sensors, and Real-time kinematic (RTK) position data are offering new perspectives for the comprehensive remote sensing applications. The combination of these sensors and light-weight and low-cost multi- or hyperspectral frame sensors in drones provides the opportunity of creating near real-time or real-time remote sensing data of target object. We have developed a system with direct georeferencing onboard drone to be used combined with hyperspectral frame cameras in real-time remote sensing applications. The objective of this study is to evaluate the real-time georeferencing comparing with post-processing solutions. Experimental data sets were captured in agricultural and forested test sites using the system. The accuracy of onboard georeferencing data were better than 0.5 m. The results showed that the real-time remote sensing is promising and feasible in both test sites. © Authors 2018. CC BY 4.0 License.Peer reviewe
Isolation and purification of ent-pimara-8(14),15-diene from engineered Aspergillus nidulans by accelerated solvent extraction combined with HPLC
Peer reviewe
Magnetosheath control of solar wind-magnetosphere coupling efficiency
We examine the role of the magnetosheath in solar wind-magnetosphere-ionosphere coupling using the Time History of Events and Macroscale Interactions during Substorms plasma and magnetic field observations in the magnetosheath together with OMNI solar wind data and auroral electrojet recordings from the International Monitor for Auroral Geomagnetic Effects (IMAGE) magnetometer chain. We demonstrate that the electric field and Poynting flux reaching the magnetopause are not linear functions of the electric field and Poynting flux observed in the solar wind: the electric field and Poynting flux at the magnetopause during higher driving conditions are lower than those predicted from a linear function. We also show that the Poynting flux normal to the magnetopause is linearly correlated with the directly driven part of the auroral electrojets in the ionosphere. This indicates that the energy entering the magnetosphere in the form of the Poynting flux is directly responsible for driving the electrojets. Furthermore, we argue that the polar cap potential saturation discussed in the literature is associated with the way solar wind plasma gets processed during the bow shock crossing and motion within the magnetosheath.Peer reviewe
Fast computation of the geoelectric field using the method of elementary current systems and planar Earth models
Bat rabies surveillance in Finland
Background: In 1985, a bat researcher in Finland died of rabies encephalitis caused by European bat lyssavirus type
2 (EBLV-2), but an epidemiological study in 1986 did not reveal EBLV-infected bats. In 2009, an EBLV-2-positive
Daubenton’s bat was detected. The EBLV-2 isolate from the human case in 1985 and the isolate from the bat in
2009 were genetically closely related. In order to assess the prevalence of EBLVs in Finnish bat populations and to
gain a better understanding of the public health risk that EBLV-infected bats pose, a targeted active surveillance
project was initiated.
Results: Altogether, 1156 bats of seven species were examined for lyssaviruses in Finland during a 28–year period
(1985–2012), 898 in active surveillance and 258 in passive surveillance, with only one positive finding of EBLV-2 in a
Daubenton’s bat in 2009. In 2010–2011, saliva samples from 774 bats of seven species were analyzed for EBLV viral
RNA, and sera from 423 bats were analyzed for the presence of bat lyssavirus antibodies. Antibodies were detected
in Daubenton’s bats in samples collected from two locations in 2010 and from one location in 2011. All seropositive
locations are in close proximity to the place where the EBLV-2 positive Daubenton’s bat was found in 2009. In
active surveillance, no EBLV viral RNA was detected.
Conclusions: These data suggest that EBLV-2 may circulate in Finland, even though the seroprevalence is low. Our
results indicate that passive surveillance of dead or sick bats is a relevant means examine the occurrence of
lyssavirus infection, but the number of bats submitted for laboratory analysis should be higher in order to obtain
reliable information on the lyssavirus situation in the country
The Pro12Ala polymorphism of the PPAR gamma 2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus
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