45 research outputs found

    Anomalous radon emanation linked to preseismic electromagnetic phenomena

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    International audienceAnomalous emanation of radon (222Rn) was observed preceding large earthquakes and is considered to be linked to preseismic electromagnetic phenomena (e.g. great changes of atmospheric electric field and ionospheric disturbances). Here we analyze atmospheric radon concentration and estimate changes of electrical conditions in atmosphere due to preseismic radon anomaly. The increase of radon emanation obeys crustal damage evolution, following a power-law of time-to-earthquake. Moreover, the radon emanation decreases the atmospheric electric field by 40%, besides influencing the maximum strength of atmospheric electric field by 104?105 V/m enough to trigger ionospheric disturbances. These changes are within the ranges observed or explaining electromagnetic phenomena associated with large earthquakes

    The transcriptional response of Caenorhabditis elegans to ivermectin exposure identifies novel genes involved in the response to reduced food intake

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    We have examined the transcriptional response of Caenorhabditis elegans following exposure to the anthelmintic drug ivermectin (IVM) using whole genome microarrays and real-time QPCR. Our original aim was to identify candidate molecules involved in IVM metabolism and/or excretion. For this reason the IVM tolerant strain, DA1316, was used to minimise transcriptomic changes related to the phenotype of drug exposure. However, unlike equivalent work with benzimidazole drugs, very few of the induced genes were members of xenobiotic metabolising enzyme families. Instead, the transcriptional response was dominated by genes associated with fat mobilization and fatty acid metabolism including catalase, esterase, and fatty acid CoA synthetase genes. This is consistent with the reduction in pharyngeal pumping, and consequential reduction in food intake, upon exposure of DA1316 worms to IVM. Genes with the highest fold change in response to IVM exposure, cyp-37B1, mtl-1 and scl-2, were comparably up-regulated in response to short–term food withdrawal (4 hr) independent of IVM exposure, and GFP reporter constructs confirm their expression in tissues associated with fat storage (intestine and hypodermis). These experiments have serendipitously identified novel genes involved in an early response of C. elegans to reduced food intake and may provide insight into similar processes in higher organisms

    Time-scale invariant changes in atmospheric radon concentration and crustal strain prior to a large earthquake

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    International audiencePrior to large earthquakes (e.g. 1995 Kobe earthquake, Japan), an increase in the atmospheric radon concentration is observed, and this increase in the rate follows a power-law of the time-to-earthquake (time-to-failure). This phenomenon corresponds to the increase in the radon migration in crust and the exhalation into atmosphere. An irreversible thermodynamic model including time-scale invariance clarifies that the increases in the pressure of the advecting radon and permeability (hydraulic conductivity) in the crustal rocks are caused by the temporal changes in the power-law of the crustal strain (or cumulative Benioff strain), which is associated with damage evolution such as microcracking or changing porosity. As the result, the radon flux and the atmospheric radon concentration can show a temporal power-law increase. The concentration of atmospheric radon can be used as a proxy for the seismic precursory processes associated with crustal dynamics
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