The impact of failures and successes on affect and self-esteem in young and older adults

Little is known about the impact of success and failure events on age-related changes in affect states and, particularly, in self-esteem levels. To fill this gap in the literature, in the present study changes in affect and self-esteem in 100 young (19 - 30 years) and 102 older adults (65-81 years) were assessed after participants experienced success and failure in a demanding cognitive task. Overall, the success-failure manipulation induced changes on affect states and on state self-esteem, not on trait self-esteem. Regarding age differences, older and young adults were affected to the same extent by experiences of successes and failures. Theoretical considerations of the empirical findings are provided in the general discussion

The selection of rain gauges and rainfall parameters in estimating intensity-duration thresholds for landslide occurrence: Case study from Wayanad (India)

© 2020 by the authors. Recurring landslides in theWestern Ghats have become an important concern for authorities, considering the recent disasters that occurred during the 2018 and 2019 monsoons. Wayanad is one of the highly affected districts in Kerala State (India), where landslides have become a threat to lives and properties. Rainfall is the major factor which triggers landslides in this region, and hence, an early warning system could be developed based on empirical rainfall thresholds considering the relationship between rainfall events and their potential to initiate landslides. As an initial step in achieving this goal, a detailed study was conducted to develop a regional scale rainfall threshold for the area using intensity and duration conditions, using the landslides that occurred during the years from 2010 to 2018. Detailed analyses were conducted in order to select the most effective method for choosing a reference rain gauge and rainfall event associated with the occurrence of landslides. The study ponders the effect of the selection of rainfall parameters for this data-sparse region by considering four different approaches. First, a regional scale threshold was defined using the nearest rain gauge. The second approach was achieved by selecting the most extreme rainfall event recorded in the area, irrespective of the location of landslide and rain gauge. Third, the classical definition of intensity was modified from average intensity to peak daily intensity measured by the nearest rain gauge. In the last approach, four different local scale thresholds were defined, exploring the possibility of developing a threshold for a uniform meteo-hydro-geological condition instead of merging the data and developing a regional scale threshold. All developed thresholds were then validated and empirically compared to find the best suited approach for the study area. From the analysis, it was observed that the approach selecting the rain gauge based on the most extreme rainfall parameters performed better than the other approaches. The results are useful in understanding the sensitivity of Intensity-Duration threshold models to some boundary conditions such as rain gauge selection, the intensity definition and the strategy of subdividing the area into independent alert zones. The results were discussed with perspective on a future application in a regional scale Landslide Early Warning System (LEWS) and on further improvements needed for this objective

Heterotrimeric G-protein subunit Gαi2 contributes to agonist-sensitive apoptosis and degranulation in murine platelets

Gαi2, a heterotrimeric G-protein subunit, regulates various cell functions including ion channel activity, cell differentiation, proliferation and apoptosis. Platelet-expressed Gαi2 is decisive for the extent of tissue injury following ischemia/reperfusion. However, it is not known whether Gαi2 plays a role in the regulation of platelet apoptosis, which is characterized by caspase activation, cell shrinkage and cell membrane scrambling with phosphatidylserine (PS) translocation to the platelet surface. Stimulators of platelet apoptosis include thrombin and collagen-related peptide (CoRP), which are further known to enhance degranulation and activation of αII bβ3-integrin and caspases. Using FACS analysis, we examined the impact of agonist treatment on activation and apoptosis in platelets drawn from mice lacking Gαi2 and their wild-type (WT) littermates. As a result, treatment with either thrombin (0.01 U/mL) or CoRP (2 μg/mL or 5 μg/mL) significantly upregulated PS-exposure and significantly decreased forward scatter, reflecting cell size, in both genotypes. Exposure to CoRP triggered a significant increase in active caspase 3, ceramide formation, surface P-selectin, and αII bβ3-integrin activation. These molecular alterations were significantly less pronounced in Gαi2-deficient platelets as compared to WT platelets. In conclusion, our data highlight a previously unreported role of Gαi2 signaling in governing platelet activation and apoptosis.Fil: Cao, Hang. Universität Tübingen; AlemaniaFil: Qadri, Syed M.. Canadian Blood Services; Canadá. McMaster University; CanadáFil: Lang, Elisabeth. Heinrich-heine-universität Düsseldorf; AlemaniaFil: Pelzl, Lisann. Universität Tübingen; AlemaniaFil: Umbach, Anja T.. Universität Tübingen; AlemaniaFil: Leiss, Veronika. Universität Tübingen; AlemaniaFil: Birnbaumer, Lutz. National Institutes of Health; Estados Unidos. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Instituto de Investigaciones Biomédicas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas; ArgentinaFil: Nürnberg, Bernd. Universität Tübingen; AlemaniaFil: Pieske, Burkert. Berlin Institute of Health; Alemania. Universitätsmedizin Berlin; AlemaniaFil: Voelkl, Jakob. Berlin Institute of Health; Alemania. Universitätsmedizin Berlin; AlemaniaFil: Gawaz, Meinrad. Universität Tübingen; AlemaniaFil: Bissinger, Rosi. Universität Tübingen; AlemaniaFil: Lang, Florian. Universität Tübingen; Alemania. Heinrich-heine-universität Düsseldorf; Alemani

Starvasi Nitrogen Dan Pengaruhnya Terhadap Biomassa Dan Protein Total Nannochloropsis SP. (Nitrogen Starvation Effect on Biomass and Crude Protein of Nannochloropsis SP)

Pengurangan nitrogen anorganik sebagai nutrien pada media kultur merupakan salahsatu metode untuk mempersingkat fase eksponensial pada kultur mikroalgae.Pengurangan nitrat anorganik pada media kultur Nannochloropsis sp hingga 50%dari konsentrasi normal pada media kultur Conwy ternyata mampu menurunkankepadatan rata-rata (sel/ml) hingga 15,16 % dan menurunkan pula kandungan proteintotal 13,93 %. Fenomena tersebut mengindikasikan bahwa pengurangan nitrogenanorganik pada media kultur berdampak negatif pada kepadatan (sel/ml) dankandungan protein total namun mampu mereduksi waktu kultur pada faseeksponensial mikroalgae Nannochloropsis sp

Long‐term research reveals multiple relationships between the abundance and impacts of a non‐native species

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147876/1/lno11029.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/147876/2/lno11029_am.pd

Pyroclastic flow dynamics and hazard in a caldera setting: application to Phlegrean Fields

Numerical simulation of pyroclastic density currents has developed significantly in recent years and is increasingly applied to volcanological research. Results from physical modeling are commonly taken into account in volcanic hazard assessment and in the definition of hazard mitigation strategies. In this work, we modeled pyroclastic density currents in the Phlegrean Fields caldera, where flows propagating along the flat ground could be confined by the old crater rims that separate downtown Naples from the caldera. The different eruptive scenarios (mass eruption rates, magma compositions, and water contents) were based on available knowledge of this volcanic system, and appropriate vent conditions were calculated for each scenario. Simulations were performed along different topographic profiles to evaluate the effects of topographic barriers on flow propagation. Simulations highlighted interesting features associated with the presence of obstacles such as the development of backflows. Complex interaction between outward moving fronts and backflows can affect flow propagation; if backflows reach the vent, they can even interfere with fountain dynamics and induce a more collapsing behavior. Results show that in the case of large events ( 108 kg/s), obstacles affect flow propagation by reducing flow velocity and hence dynamic pressure in distal regions, but they cannot stop the advancement of flows. Deadly conditions (in terms of temperature and ash concentration) characterize the entire region invaded by pyroclastic flows. In the case of small events (2.5 107 kg/s), flows are confined by distal topographic barriers which provide valuable protection to the region beyond

Anticipating Stream Ecosystem Responses to Climate Change: Toward Predictions That Incorporate Effects via Land–Water Linkages

Climate change (CC) is projected to increase the frequency and severity of natural disturbances (wildfires, insect outbreaks, and debris flows) and shift distributions of terrestrial ecosystems on a global basis. Although such terrestrial changes may affect stream ecosystems, they have not been incorporated into predictions of stream responses to CC. Here, we introduce a conceptual framework to evaluate to what extent responses of streams to CC will be driven by not only changes in thermal and hydrologic regimes, but also alterations of terrestrial processes. We focused on forested water-sheds of western North America because this region is projected to experience CC-induced alteration of terrestrial processes. This provided a backdrop for investigating interactive effects of climate and terrestrial responses on streams. Because stream responses to terrestrial processes have been well-studied in contexts largely independent of CC research, we synthesized this knowledge to demonstrate how CC-induced alterations of terrestrial ecosystems may affect streams. Our synthesis indicated that altered terrestrial processes will change terrestrial–aquatic linkages and autotrophic production, potentially yielding greater sensitivity of streams to CC than would be expected based on shifts in temperature and precipitation regime alone. Despite uncertainties that currently constrain predictions regarding stream responses to these additional pathways of change, this synthesis highlighted broader effects of CC that require additional research. Based on widespread evidence that CC is linked to changing terrestrial processes, we conclude that accurate predictions of CC effects on streams may be coupled to the accuracy of predictions for long-term changes in terrestrial ecosystems

Fast closed-loop optimal control of ultracold atoms in an optical lattice

We present experimental evidence of the successful closed-loop optimization of the dynamics of cold atoms in an optical lattice. We optimize the loading of an ultracold atomic gas minimizing the excitations in an array of one-dimensional tubes (3D-1D crossover) and we perform an optimal crossing of the quantum phase-transition from a Superfluid to a Mott-Insulator in a three-dimensional lattice. In both cases we enhance the experiment performances with respect to those obtained via adiabatic dynamics, effectively speeding up the process by more than a factor three while improving the quality of the desired transformation