CASE STUDY: Feed Intake and Performance of Heifers Sired by High- or Low-Residual Feed Intake Angus Bulls

The objective of this project was to investigate the effects of selecting sires for residual feed intake (RFI) on the performance of their daughters. Bulls with low or high estimated breeding values (EBV) for RFI were selected from the Angus Society of Australia sire summary and mated to Angus cross commercial cows at the Kansas State University Cow-Calf Unit in 2005 and 2006. The average EBV of low- and high-RFI bulls were −0.55 and 0.27 kg DM, respectively. Heifers born in 2006 were tested for feed intake in 2 groups (n = 24, n = 26), and heifers born in 2007 (n = 42) were sent to a commercial bull test facility for feed intake and BW gain tests. Body weights were collected every 14 d and used to calculate midtest BW and ADG. Actual feed intake was regressed on midtest metabolic BW and ADG to calculate an expected feed intake for each heifer. Residual feed intake was calculated by subtracting the expected intake from the actual intake. There were no significant differences between heifers sired by lowor high-RFI EBV bulls in RFI, feed intake, G:F, or BW gain (P \u3e 0.05). Heifers in this study were being developed on a less energy-dense diet than the diet used to rank their sires. Genetic differences in RFI calculated in growing bulls may not have been expressed on the lower plane of nutrition of these developing heifers

CASE STUDY: Feed Intake and Performance of Heifers Sired by High- or Low-Residual Feed Intake Angus Bulls

The objective of this project was to investigate the effects of selecting sires for residual feed intake (RFI) on the performance of their daughters. Bulls with low or high estimated breeding values (EBV) for RFI were selected from the Angus Society of Australia sire summary and mated to Angus cross commercial cows at the Kansas State University Cow-Calf Unit in 2005 and 2006. The average EBV of low- and high-RFI bulls were −0.55 and 0.27 kg DM, respectively. Heifers born in 2006 were tested for feed intake in 2 groups (n = 24, n = 26), and heifers born in 2007 (n = 42) were sent to a commercial bull test facility for feed intake and BW gain tests. Body weights were collected every 14 d and used to calculate midtest BW and ADG. Actual feed intake was regressed on midtest metabolic BW and ADG to calculate an expected feed intake for each heifer. Residual feed intake was calculated by subtracting the expected intake from the actual intake. There were no significant differences between heifers sired by lowor high-RFI EBV bulls in RFI, feed intake, G:F, or BW gain (P \u3e 0.05). Heifers in this study were being developed on a less energy-dense diet than the diet used to rank their sires. Genetic differences in RFI calculated in growing bulls may not have been expressed on the lower plane of nutrition of these developing heifers

Gaggle on the Gavel: Designing an Interactive Website to Create a Community of Lawyers

Law is behind other industries and professions in its implementation of technolo-gy that could make the practice of law and the delivery of legal services more ef-fective and satisfying. Although there has been considerable development in le-gal technology over the past few years, research identified the need for an interac-tive LinkedIn-style online community for lawyers to communicate other lawyers. Such a community would be particularly beneficial for solo practitioners, lawyers in small firms and lawyers in rural communities and would also provide a con-venient way to connect with lawyers for referrals and recommendations, for spe-cialized expertise and to develop contacts in different geographic locations. Ten-tatively titled Gaggle on the Gavel is an attempt to create such a community that would gather a number of attractive features and functionality under one umbrella and be compliant with the rules of professional conduct with respect to client con-fidentiality, security, advertising and solicitation. A system has been designed, prototyped and revised based on feedback from a focus group of lawyers

Deweyan tools for inquiry and the epistemological context of critical pedagogy

This article develops the notion of resistance as articulated in the literature of critical pedagogy as being both culturally sponsored and cognitively manifested. To do so, the authors draw upon John Dewey\u27s conception of tools for inquiry. Dewey provides a way to conceptualize student resistance not as a form of willful disputation, but instead as a function of socialization into cultural models of thought that actively truncate inquiry. In other words, resistance can be construed as the cognitive and emotive dimensions of the ongoing failure of institutions to provide ideas that help individuals both recognize social problems and imagine possible solutions. Focusing on Dewey\u27s epistemological framework, specifically tools for inquiry, provides a way to grasp this problem. It also affords some innovative solutions; for instance, it helps conceive of possible links between the regular curriculum and the study of specific social justice issues, a relationship that is often under-examined. The aims of critical pedagogy depend upon students developing dexterity with the conceptual tools they use to make meaning of the evidence they confront; these are background skills that the regular curriculum can be made to serve even outside social justice-focused curricula. Furthermore, the article concludes that because such inquiry involves the exploration and potential revision of students\u27 world-ordering beliefs, developing flexibility in how one thinks may be better achieved within academic subjects and topics that are not so intimately connected to students\u27 current social lives, especially where students may be directly implicated

Redox-active and DNA-binding coordination complexes of clotrimazole

DNA interactions of anticancer mononuclear Cu2+, Co2+, Zn2+, and Ni2+ complexes with the biologically active ligand clotrimazole (clotri) are reported. To fully characterize DNA binding modes for these complexes of the formulae [M(clotri)2Cl2]·nH2O (1–4), [M(clotri)2Br2]·nH2O (5,6), [M(clotri)3NO3]NO3·nH2O (9), and [M(clotri)3(NO3)2] (10), circular dichroism (CD) and linear dichroism (LD) spectroscopy, UV melting experiments, atomic force microscopy (AFM) and ethidium bromide (EtBr) displacement methods were used. Results indicate mixed electrostatic interactions, possibly through groove binding, that result in accretion and coiling of DNA. Electrochemical studies indicate that the Cu2+ complex 9 readily reduces to the reactive-oxygen-species-generating Cu+, which oxidatively damages DNA. There is a subtle correlation between log P values, calculated electrostatic potentials, and cytotoxicity of the complexes. The extent of cell-nucleus DNA-metal adduct formation in the HeLa cervix-uterine carcinoma cell line does not necessarily correlate with cytotoxicity, indicating that the nature of DNA lesions may be crucial to activity