238 research outputs found

    Innledende undersøkelse av forurensning fra deponiet til Setesdalen renovasjon, Syrtveit

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    Årsliste 2004Setesdal renovasjo

    Trace metals in Norwegian surface waters, soils, and lake sediments - relation to atmospheric deposition

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    Årsliste 2006This report presents results from simultaneous trace metal surveys 1995 in Norway on atmospheric deposition based on moss analysis, the humic layer of soils, lake sediments, and surface waters. The samples of sediment and water were not taken at the same geographical locations as the moss and soil samples, but a direct comparison of the data sets is still feasible. Retrospective studies indicate that long-range transport has been a significant source of heavy metal contamination in southern Norway for the last couple of centuries, but has been considerably reduced over the last 20 years. Long-range transboundary air-pollution (LRTAP) is a very important source of of heavy metal contamination in the Norwegian environment, in particular for As, Cd, Sb, Hg, Pb, and Bi but also to some extent for V, Zn, Se, Mo, Sn, Te, and Tl. The corresponding geographic trend is reflected in samples of moss, surface soil, lake sediment, and lake water. A similar geographic trend is also indicated in the water samples for Be and Co, but not in samples of moss or soil humus. This is interpreted as a possible result of higher acidic deposition in the south wich leads to enhanced weathering of mineral matter and subsequent leaching to the lakes.Norges forskningsråd, (PROFO

    HybridMingler: Towards Mixed-Reality Support for Mingling at Hybrid Conferences

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    Mingling, the activity of ad-hoc, private, opportunistic conversations ahead of, during, or after breaks, is an important socializing activity for attendees at scheduled events, such as in-person conferences. The Covid-19 pandemic had a dramatic impact on the way conferences are organized, so that most of them now take place in a hybrid mode where people can either attend on-site or remotely. While on-site attendees can resume in-person mingling, hybrid modes make it challenging for remote attendees to mingle with on-site peers. In addressing this problem, we propose a collaborative mixed-reality (MR) concept, including a prototype, called HybridMingler. This is a distributed MR system supporting ambient awareness and allowing both on-site and remote conference attendees to virtually mingle. HybridMingler aims to provide both on-site and remote attendees with a spatial sense of co-location in the very same venue location, thus ultimately improving perceived presence

    Variation in the achievement of HbA1c, blood pressure and LDL cholesterol targets in type 2 diabetes in general practice and characteristics associated with risk factor control.

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    Aims To identify population, general practitioner, and practice characteristics associated with the achievement of HbA1c, blood pressure and LDL cholesterol targets, and to describe variation in the achievement of risk factor control. Methods We conducted a cross‐sectional survey of 9342 people with type 2 diabetes, 281 general practitioners and 77 general practices in Norway. Missing values (7.4%) were imputed using multiple imputation by chained equations. We used three‐level logistic regression with the achievement of HbA1c, blood pressure and LDL cholesterol targets as dependent variables, and factors related to population, general practitioners, and practices as independent variables. Results Treatment targets were achieved for HbA1c in 64%, blood pressure in 50%, and LDL cholesterol in 52% of people with type 2 diabetes, and 17% met all three targets. There was substantial heterogeneity in target achievement among general practitioners and among practices; the estimated proportion of a GPs diabetes population at target was 55–73% (10–90 percentiles) for HbA1c, 36–63% for blood pressure, and 47–57% for LDL cholesterol targets. The models explained 11%, 5% and 14%, respectively, of the total variation in the achievement of HbA1c, blood pressure and LDL cholesterol targets. Use among general practitioners of a structured diabetes form was associated with 23% higher odds of achieving the HbA1c target (odds ratio 1.23, 95% confidence interval (CI) 1.02–1.47) and 17% higher odds of achieving the LDL cholesterol target (odds ratio 1.17, 95% CI 1.01–1.35). Conclusions Clinical diabetes management is difficult, and few people meet all three risk factor control targets. The proportion of people reaching target varied among general practitioners and practices. Several population, general practitioner and practice characteristics only explained a small part of the total variation. The use of a structured diabetes form is recommended.publishedVersio

    Forurensningssituasjonen i Mjøsa med tilløpselver 2012

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    Denne rapporten gir en kortfattet oversikt over de viktigste resultatene fra overvåkingen i Vannområde Mjøsa i 2012. Undersøkelsene er utført på oppdrag fra Vassdragsforbundet for Mjøsa med tilløpselver. Overvåkingen omfatter fysiske, kjemiske og biologiske forhold i Mjøsas hovedvannmasser, hygieniske forhold, konsentrasjoner og transport av næringsstoffer i de seks største tilløpselvene samt i utløpselva Vorma. Videre er biologiske forhold i utvalgte tilløpselver undersøkt. Årsrapporten for 2012 gir en fyldigere presentasjon av måledata og vurderinger. Data presenteres også fortløpende gjennom NIVAs overvåkingsverktøy Aquamonitor.Vassdragsforbundet for Mjøsa med tilløpselve

    Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells

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    Mutations in the gene encoding the digestive enzyme carboxyl ester lipase (CEL) are linked to pancreatic disease. The CEL variant denoted CEL-HYB predisposes to chronic pancreatitis, whereas the CEL-MODY variant causes MODY8, an inherited disorder of endocrine and exocrine pancreatic dysfunction. Both pathogenic variants exhibit altered biochemical and cellular properties compared with the normal CEL protein (CEL-WT, wild type). We here aimed to investigate effects of CEL variants on pancreatic acinar and ductal cell lines. Following extracellular exposure, CEL-HYB, CEL-MODY, and CEL-WT were endocytosed. The two pathogenic CEL proteins significantly reduced cell viability compared with CEL-WT. We also found evidence of CEL uptake in primary human pancreatic acinar cells and in native ductal tissue. Moreover, coexpression of CEL-HYB or CEL-MODY with CEL-WT affected secretion of the latter, as CEL-WT was observed to accumulate intracellularly to a higher degree in the presence of either pathogenic variant. Notably, in coendocytosis experiments, both pathogenic variants displayed a modest effect on cell viability when CEL-WT was present, indicating that the normal protein might diminish toxic effects conferred by CEL-HYB and CEL-MODY. Taken together, our findings provide valuable insight into how the pathogenic CEL variants predispose to pancreatic disease and why these disorders develop slowly over time.publishedVersio

    Direct conversion of methane to aromatics in a catalytic co-ionic membrane reactor

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    [EN] Nonoxidative methane dehydroaromatization (MDA: 6CH(4) C6H6 + 9H(2)) using shape-selective Mo/zeolite catalysts is a key technology for exploitation of stranded natural gas reserves by direct conversion into transportable liquids. However, this reaction faces two major issues: The one-pass conversion is limited by thermodynamics, and the catalyst deactivates quickly through kinetically favored formation of coke. We show that integration of an electrochemical BaZrO3-based membrane exhibiting both proton and oxide ion conductivity into an MDA reactor gives rise to high aromatic yields and improved catalyst stability. These effects originate from the simultaneous extraction of hydrogen and distributed injection of oxide ions along the reactor length. Further, we demonstrate that the electrochemical co-ionic membrane reactor enables high carbon efficiencies (up to 80%) that improve the technoeconomic process viability.This work was supported by the Research Council of Norway (grants 195912, 210418, 210765, and 219194) and the Spanish government (grants SEV-2012-0267 and ENE2014-57651). We thank the ALBA Synchrotron Light Laboratory for beam time provision. C.K. and P.K.V. have applied for a patent based on this work (PCT/EP2014/071697). Experimental data are available online at ftp://itqrepositorio.itq.upv.es/pub/.HernĂĄndez Morejudo, S.; ZanĂłn GonzĂĄlez, R.; EscolĂĄstico RozalĂŠn, S.; Yuste Tirados, I.; Malerod Fjeld, H.; Vestre, PK.; Coors, WG.... (2016). Direct conversion of methane to aromatics in a catalytic co-ionic membrane reactor. Science. 353(6299):563-566. https://doi.org/10.1126/science.aag0274S563566353629
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