Quantum Symmetries and Stringy Instantons

The quantum symmetry of many \LG\ orbifolds appears to be broken by Yang-Mills instantons. However, isolated Yang-Mills instantons are not solutions of string theory: They must be accompanied by gauge anti-instantons, gravitational instantons, or topologically non-trivial configurations of the $H$ field. We check that the configurations permitted in string theory do in fact preserve the quantum symmetry, as a result of non-trivial cancellations between symmetry breaking effects due to the various types of instantons. These cancellations indicate new constraints on \LG\ orbifold spectra and require that the dilaton modulus mix with the twisted moduli in some \LG\ compactifications. We point out that one can find similar constraints at all fixed points of the modular group of the moduli space of vacua.Comment: 14pp, harvmac, PUPT--146

Overview of pathogenesis of systemic sclerosis

The aetiology of SSc is subject to ongoing research, as the precise events that underlie the development of this disease remain unclear. The pathogenesis is known to involve endothelium, epithelium, fibroblasts, innate and adaptive immune systems and their component immunological mediators. Endothelial cell damage may be the initiating factor, but the precise triggering event(s) remain elusive. Angiogenesis also appears to be dysregulated. Vasculopathy shows similarities in different organs (e.g. pulmonary arterial hypertension, renal disease, digital tip ulcers). Endothelin-1 is a potent mediator of vasculopathy, and hence represents a highly relevant target for intervention of vascular features in SS

2D String Theory Coupled to Quantum Gravity

We consider self-avoiding Nambu-Goto open strings on a random surface. We have shown that the partition function of such a string theory can be calculated exactly. The string susceptibility for the disk is evaluated to be $-\frac{1}{2}$. We also consider modifications of the Nambu-Goto action which are exactly soluble on a random surface.Comment: 12 pages, LaTex, KEK-TH-36

Continuum Annulus Amplitude from the Two-Matrix Model

An explicit expression for continuum annulus amplitudes having boundary lengths $\ell_{1}$ and $\ell_{2}$ is obtained from the two-matrix model for the case of the unitary series; $(p,q) = (m + 1, m)$. In the limit of vanishing cosmological constant, we find an integral representation of these amplitudes which is reproduced, for the cases of the $m = 2~(c=0)$ and the $m \rightarrow \infty~(c=1)$, by a continuum approach consisting of quantum mechanics of loops and a matter system integrated over the modular parameter of the annulus. We comment on a possible relation to the unconventional branch of the Liouville gravity.Comment: 9 pages, OU-HET 190, revised version. A part of the conclusions has been corrected. A new result on integral representation of the annulus amplitudes has been adde

Field condensations and Noncritical String for c>1

Quantum theory of 2d gravity for $c>1$ is examined as a non-critical string theory by taking account of the loop-correction of open strings whose end points are on the 2d world surface of the closed string. This loop-correction leads to a conformal anomaly, and we obtain a modified target-space action which implies a new phase of the non-critical closed-string. In this phase, the dual field of the gauge field, which lives on the boundary, condenses and the theory can be extended to $c>1$ without any instability.Comment: 17 pages, Latex, no figur

Baby Universes Revisited

The behaviour of baby universes has been an important ingredient in understanding and quantifying non-critical string theory or, equivalently, models of two-dimensional Euclidean quantum gravity coupled to matter. Within a regularized description based on dynamical triangulations, we amend an earlier conjecture by Jain and Mathur on the scaling behaviour of genus-$g$ surfaces containing particular baby universe `necks', and perform a nontrivial numerical check on our improved conjecture.Comment: 10 pages, 1 figur

FOREVER: Fault/intrusiOn REmoVal through Evolution & Recovery

The goal of the FOREVER project is to develop a service for Fault/intrusiOn REmoVal through Evolution & Recovery. In order to achieve this goal, our work addresses three main tasks: the definition of the FOREVER service architecture; the analysis of how diversity techniques can improve resilience; and the evaluation of the FOREVER service. The FOREVER service is an important contribution to intrustion-tolerant replication middleware and significantly enhances the resilience

On the validity of ADM formulation in 2D quantum gravity

We investigate 2d gravity quantized in the ADM formulation, where only the loop length $l(z)$ is retained as a dynamical variable of the gravitation, in order to get an intuitive physical insight of the theory. The effective action of $l(z)$ is calculated by adding scalar fields of conformal coupling, and the problems of the critical dimension and the time development of $l$ are addressed.Comment: 12 page