A Simple Methodology for Conversion of Mouse Monoclonal Antibody to Human-Mouse Chimeric Form

10.1155/2013/716961Clinical and Developmental Immunology2013Article number 716961,6 page

Facile Template In-Situ Fabrication of ZnCo2O4 Nanoparticles with Highly Photocatalytic Activities under Visible-Light Irradiation

High specific surface area ZnCo2O4 nanoparticles were prepared via a sacrificial template accelerated hydrolysis by using nanoparticles of ZnO with highly polar properties as a template. The obtained ZnCo2O4 nanoparticles were characterized by the method of scanning electron microscopy (SEM), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET) surface area measurements, Transmission electron microscopy (TEM), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS). The obtained nanoparticles were performed as a photocatalyst for the degradation of methylene blue in aqueous solution under visible irradiation. The photocatalytic degradation rate of methylene blue onto the synthesized ZnCo2O4 was higher than that of commercial ZnO and synthesized ZnO template. Copyright © 2019 BCREC Group. All rights reserved

Light extraction efficiency enhancement of colloidal quantum dot light-emitting diodes using large-scale nanopillar arrays

Cataloged from PDF version of article.A colloidal quantum dot light-emitting diode (QLED) is reported with substantially enhanced light extraction efficiency by applying a layer of large-scale, low-cost, periodic nanopillar arrays. Zinc oxide nanopillars are grown on the glass surface of the substrate using a simple, efficient method of non-wetting templates. With the layer of ZnO nanopillar array as an optical outcoupling medium, a record high current efficiency (CE) of 26.6 cd/A is achieved for QLEDs. Consequently, the corresponding external quantum efficiency (EQE) of 9.34% reaches the highest EQE value for green-emitting QLEDs. Also, the underlying physical mechanisms enabling the enhanced light-extraction are investigated, which leads to an excellent agreement of the numerical results based on the mode theory with the experimental measurements. This study is the first account for QLEDs offering detailed insight into the light extraction efficiency enhancement of QLED devices. The method demonstrated here is intended to be useful not only for opening up a ubiquitous strategy for designing high-performance QLEDs but also with respect to fundamental research on the light extraction in QLEDs

Energy-loss Function for Lead

We study the energy-loss function for lead in the framework of the time-dependent density functional theory, using the full-potential linearized augmented plane-wave plus local orbitals method. The ab initio calculations are performed in the adiabatic local density approximation. The comparison between the obtained energy-loss function for zero momentum transfer with those from reflection electron energy loss spectroscopy measurements and from first-principles calculations shows good agreement

Building the hospital event-based surveillance system in Viet Nam: a qualitative study to identify potential facilitators and barriers for event reporting

Introduction: Hospitals are a key source of information for the early identification of emerging disease outbreaks and acute public health events for risk assessment, decision-making, and public health response. The objectives of this study were to identify potential facilitators and barriers for reporting of unusual events from the curative sector to the preventive medicine system in Viet Nam. Methods: In 2016, we conducted 18 semi-structured in-depth interviews and 9 focus group discussions with representatives from the curative and preventive medicine sectors in four provinces. We transcribed the interviews and focus group discussions and conducted a thematic analysis of the factors that appeared to affect public health event reporting. Results: We identified five major themes. Firstly, the lack of a legal framework to guide reporting meant there was an over-reliance on internal procedures. Secondly, participants reported the importance of an enabling environment to facilitate reporting such as leadership support and having focal points for reporting. Thirdly, potential benefits for reporting were seen such as support during outbreaks and receiving feedback. Fourthly, some challenges prohibited timely reporting such as not perceiving reporting to be the task of the curative sector and hesitancy to report without laboratory confirmation. Finally, the limited resources and specialist capacities in remote areas hindered timely detection and reporting of unusual events. Discussion: This study identified potential opportunities to promote the detection and reporting of unusual events from health care workers to the public health sector, and thus improving the overall health security system in Viet Nam and beyond

Long Time to Diagnosis of Medulloblastoma in Children Is Not Associated with Decreased Survival or with Worse Neurological Outcome

International audienceBACKGROUND: The long time to diagnosis of medulloblastoma, one of the most frequent brain tumors in children, is the source of painful remorse and sometimes lawsuits. We analyzed its consequences for tumor stage, survival, and sequelae. PATIENTS AND METHODS: This retrospective population-based cohort study included all cases of pediatric medulloblastoma from a region of France between 1990 and 2005. We collected the demographic, clinical, and tumor data and analyzed the relations between the interval from symptom onset until diagnosis, initial disease stage, survival, and neuropsychological and neurological outcome. RESULTS: The median interval from symptom onset until diagnosis for the 166 cases was 65 days (interquartile range 31-121, range 3-457). A long interval (defined as longer than the median) was associated with a lower frequency of metastasis in the univariate and multivariate analyses and with a larger tumor volume, desmoplastic histology, and longer survival in the univariate analysis, but not after adjustment for confounding factors. The time to diagnosis was significantly associated with IQ score among survivors. No significant relation was found between the time to diagnosis and neurological disability. In the 62 patients with metastases, a long prediagnosis interval was associated with a higher T stage, infiltration of the fourth ventricle floor, and incomplete surgical resection; it nonetheless did not influence survival significantly in this subgroup. CONCLUSIONS: We found complex and often inverse relations between time to diagnosis of medulloblastoma in children and initial severity factors, survival, and neuropsychological and neurological outcome. This interval appears due more to the nature of the tumor and its progression than to parental or medical factors. These conclusions should be taken into account in the information provided to parents and in expert assessments produced for malpractice claims