The Challenges Encountered in the Application of Kodaly Method in Turkey

Kodaly is a method used in many countries, particularly in Hungary. The method is based upon the introduction of singing and the applied aspect of music with children at early ages, by which they are ensured with a more qualified and permanent music education.This research focuses on possible actions to be taken in order to increase the quality of music education; as well as the opportunities offered by Kodaly method within this framework. With this in mind, the question “What are the challenges encountered in the application of Kodaly method?” is tried to be answered. The aim of this study is to point out the difficulties in the application of Kodaly Method, which is effectively applied in many countries, in Turkey and provide suggestions regarding its utilization. The study is based on descriptive methods and has been conducted by means of reviewing the relevant literature. Besides, opinions of an instructor using this method for five years have been consulted and several problems have been identified in line with these opinions. The research is considered significant in terms of identifying difficulties in the application of Kodaly Method in Turkey and suggesting solutions to them. It is also believed to shed light upon those who are willing to apply this method. In that sense, this study is believed to serve as a guideline in music education

Diagnosis of comorbid migraine without aura in patients with idiopathic/genetic epilepsy based on the gray zone approach to the International Classification of Headache Disorders 3 criteria

BackgroundMigraine without aura (MwoA) is a very frequent and remarkable comorbidity in patients with idiopathic/genetic epilepsy (I/GE). Frequently in clinical practice, diagnosis of MwoA may be challenging despite the guidance of current diagnostic criteria of the International Classification of Headache Disorders 3 (ICHD-3). In this study, we aimed to disclose the diagnostic gaps in the diagnosis of comorbid MwoA, using a zone concept, in patients with I/GEs with headaches who were diagnosed by an experienced headache expert.MethodsIn this multicenter study including 809 consecutive patients with a diagnosis of I/GE with or without headache, 163 patients who were diagnosed by an experienced headache expert as having a comorbid MwoA were reevaluated. Eligible patients were divided into three subgroups, namely, full diagnosis, zone I, and zone II according to their status of fulfilling the ICHD-3 criteria. A Classification and Regression Tree (CART) analysis was performed to bring out the meaningful predictors when evaluating patients with I/GEs for MwoA comorbidity, using the variables that were significant in the univariate analysis.ResultsLonger headache duration (<4 h) followed by throbbing pain, higher visual analog scale (VAS) scores, increase of pain by physical activity, nausea/vomiting, and photophobia and/or phonophobia are the main distinguishing clinical characteristics of comorbid MwoA in patients with I/GE, for being classified in the full diagnosis group. Despite being not a part of the main ICHD-3 criteria, the presence of associated symptoms mainly osmophobia and also vertigo/dizziness had the distinguishing capability of being classified into zone subgroups. The most common epilepsy syndromes fulfilling full diagnosis criteria (n = 62) in the CART analysis were 48.39% Juvenile myoclonic epilepsy followed by 25.81% epilepsy with generalized tonic-clonic seizures alone.ConclusionLonger headache duration, throbbing pain, increase of pain by physical activity, photophobia and/or phonophobia, presence of vertigo/dizziness, osmophobia, and higher VAS scores are the main supportive associated factors when applying the ICHD-3 criteria for the comorbid MwoA diagnosis in patients with I/GEs. Evaluating these characteristics could be helpful to close the diagnostic gaps in everyday clinical practice and fasten the diagnostic process of comorbid MwoA in patients with I/GEs

Sürdürülebilir tarım için yöneylem araştırması modelleri

TEZ6426Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 2007.Kaynakça (s.57-61) var.vii, 81 s. : res. ; 29 cm.In the study, a mathematical approach, which was improved by operations research techniques, was exposed for sustainable agricultural concept for the meeting the requirements of all the world population and to leave more livable world for next generations. The mixed integer mathematical model was developed for sustainable agriculture. The improved model was run with Lingo 8.0. that is used as a optimization program with inputs of Adana's Yumurtalık region, which were obtained from the official associations. At the end of the study, the results of model were discussed with the studies in the literature.Bu çalısmada, dünya nüfusunun tamamının ihtiyaçlarının karsılanabilmesi ve gelecekteki nesillere daha yasanılabilir bir dünya bırakılabilmesi için önerilen sürdürülebilir tarım kavramına yöneylem arastırması teknikleri ile matematiksel bir yaklasım ortaya konmustur. Sürdürülebilir tarım için karma tamsayılı matematiksel bir model gelistirilmistir. Gelistirilen model, eniyileme paket programlarından biri olarak kullanılan Lingo 8.0 programına aktarılmıs ve resmi kurumlardan alınan Adana'nın YumurtalıkBu çalışma Ç.Ü. Bilimsel Araştırma Projeleri Birimi Tarafından Desteklenmiştir. Proje No

The usage of bioactive extracts recovered from grape pomace in the enrichment of some fruit juices

Bu araştırma kapsamında, hammadde olarak üzümün sadece suyunu kullanarak üretim yapan işletmelerde ortaya çıkan bir tarımsal atık olan cibrenin fenolik bileşiklerinin geri kazanılarak, fonksiyonel zenginleştirici olarak meyve sularında kullanım olanakları incelenmiştir. Ekstraksiyon uygulaması olarak, yeni nesil yeşil ekstraksiyon tekniklerinden olan ultrasonik destekli ekstraksiyon tercih edilmiştir. Ekstraksiyon parametreleri incelenen optimizasyon çalışmalarına göre belirlenmiştir. Araştırma kapsamında hem cibre hem de cibreyi oluşturan kabuk ve çekirdek kısımlarında ayrı ayrı ekstraksiyon yapılmıştır. Elde edilen ekstraktlar vişne suyu, karışık meyve suyu ve üzüm suyuna %2,5, %5, %7,5 ve %10 oranlarında ilave edilerek fenolik bileşiklerce zenginleştirilmiş meyve suları elde edilmiştir. Elde edilen meyve sularında fenolik bileşik içeriği ve duyusal özellikleri bakımından hangi ekstrakt çeşidinin, hangi oranda ilave edilmesinin daha uygun olacağının değerlendirilmesi yapılmıştır. Elde edilen analiz sonuçlarına göre cibre, kabuk ve çekirdek ekstraktlarında toplam fenolik bileşik içeriği sırasıyla çekirdek 139,233 mg GAE/mL, cibre 115,167 mg GAE/mL ve kabuk 85,500 mg GAE/mL olarak belirlenmiştir. Analiz sonuçlarına göre tüm meyve suyu çeşitlerinde %7,5 cibre ve %10 kabuk ekstraktı oranına kadar tüm konsantrasyonlarda fonksiyonel olarak zenginleştirilmiş bir meyve suyu üretim potansiyeli olduğu belirlenmiştir. İlaveten, üzüm suyu ise aroma profili bakımından ekstraktlarla daha uyumlu olduğu için çekirdek ekstraktı olan örneklerde %5e kadar ilave edildiğinde kabul sınırlarının içinde kalmıştır.Within the content of this research, the possibilities of using the phenolic compounds of the grape pomace, which is an agricultural waste produced by the plants that use only the juice of the grape as raw material, in fruit juices as functional enricher were examined. As the extraction application, ultrasonic-assisted extraction, which is one of the new generation gren extraction techniques, has been preferred. Extraction parameters were determined according to the optimization studies examined.Within the scope of there search, grape pomaces and the parts of forming pomace both the skin and the seeds were extracted separately. The extracts were added to sour cherry juice, mixed fruit juice and grape juice at 2.5%, 5%, 7.5% and 10%, and fruit juices enriched with phenolic compounds were obtained. In terms of phenolic compound content and sensory properties of the fruit juices was evaluated which type of extract and what proportions would be more appropriate to add. According to the analysis results, the total phenolic compound content in grape pomace, skin and seed extracts was determined as 139.233 mg GAE/mL for seed, 115.167 mg GAE/mL for grape pomace and 85,500 mg GAE/mL for skin. According to the analysis results, in all fruit juices in all concentrations up to 7.5% grape pomace and 10% skin extract there is a fruit juice production potential that is enriched functionally. In addition, since grape juice is more compatible with extracts in terms of aroma profile, it remained within the acceptance limits when added up to 5% in samples with seed extracts

The cervical smear epithelial cell abnormality data of 354,725 patients from 38 pathology laboratories and 45 hospitals in Turkey

WOS: 000388614501035

Baş ve boyun bölgesinde çoklu metastaz yapmış solunum sıkıntısına yol açan dev karsinoma ex pleomorfik adenom

Carcinoma ex pleomorphic adenoma is a rare tumor that results from the carcinomatous transformation of a primer or recurrent pleomorphic adenoma. A 75-year-old male patient presented with a solid mass in his neck and respiratory failure. The patient had a 20-year history of this disease. A clinical examination revealed a solid and fixed mass with a number of lobules that fully pervaded the 2nd region on the left side of the neck, arising from the left parotid. Facial nerve functions were good. Furthermore, solid and mobile masses were identified in the frontal region, below the scalp, in the auricle of the left ear and the in left superficial layer of the sternocleidomastoid muscle. An oropharynx examination revealed that the left tonsil region had passed to the midline of the neck, pushing the uvula under the effect of the mass. In an MRI of the neck, the image involved the masticatory and parapharyngeal area that filled in the left parotid on the skull base, narrowed the Rosenmuller fossa on the left superior and obliterated significantly the air lumen on the oropharynx level. The mass extended to the hyoid bone in the caudal and to the bottom of skinto-skin in parotid region. The measurable size of the mass was 9 x 10 cm. The patient underwent a total parotidectomy and a left neck dissection in surgery, and in addition, other masses in the neck and the head were excised.Karsinoma ex pleomorfik adenom primer veya rekürren pleomorfik adenomun karsinomatöz transformasyonu olan nadir bir tümördür. Bu tümörlerin en yaygın klinik prezentasyonu parotis bezinde sert kitle olmasıdır. Bizim olgumuz boyunda kitle ve solunum sıkıntısı ile başvuran 75 yaşındaki erkek hastaydı. Hastanın 20 yıllık bir hikayesi bulunmaktaydı. Klinik muayenede sol parotisten kaynaklanan boynunun sol tarafında 2. bölgeyi de tamamen doldurmuş sert, fikse, çok sayıda lobüllü olan kitle mevcuttu. Fasyal sinir fonksiyonları salimdi. Ayrıca frontal bölgede, skalp altında, sol kulak aurikulasında ve sol sternokleidomastoid kas yüzeyelinde sert, mobil kitleleri mevcuttu. Orofarenks muayenesinde kitle etkisiyle sol tonsil loju uvulayı da iterek orta hattı belirgin bir şekilde geçmişti. Boyun MR’ında solda kafa tabanında, parotit alanı dolduran, süperiorda rosenmüller fossa seviyesinde, rossen müller fossayı soldan daraltan, orta hatta doğru uzanım gösteren, orofarenks düzeyinde hava lümenini belirgin derecede oblitere eden, mastikatör alan, parafarengeal alanı kaplayan parotis lojunda cilt-cilt altına doğruda uzanan, kaudalde hyoid kemik seviyesine kadar uzanan, ölçülebilen boyutu 9x10 cm boyutlarında T1 hafif hiperintens T2 hiperintens, lobüle konturlu, kontrast tutan solid kitle izlenmekteydi. Hastaya cerrahi olarak total parotidektomi ve sol boyun diseksiyonu uygulandı. Ayrıca baştaki ve boyundaki diğer kitleler de eksize edildi. Parotisteki kitle karsinoma ex pleomorfik adenom, baş ve boyun bölgesindeki çıkarılan diğer kitlelerin patolojik tanıları ise karsinoma ex pleomorfik adenom metastazı olarak rapor edildi. Lokal olarak agresif seyreden bu tümörlerin solunum sıkıntısna yol açacak şekilde boyutunun büyük olması, baş ve boyun bölgesinde yüzeyel olarak cildin hemen altında multiple metastazlara yol açması çok nadir olarak görülmektedir

Immunocytoexpression profile of ProExC in smears interpreted as ASC-US, ASC-H, and cervical intraepithelial lesion

WOS: 000393891700007PubMed ID: 28182079Aims: We aimed to investigate the immunocytoexpression profiles of a novel assay ProEx C for topoisomerase II alpha (TOP2A) and minichromosome maintenance protein 2 (MCM2) in abnormal interpreted smears. Settings and Design: Screening programs with Papanicolaou smear and high risk group human papilloma virus testing have yielded a dramatic reduction of cervical cancer incidence. However, both of these tests have limited specificity for the detection of clinically significant cervical high grade lesions. ProEx C for topoisomerase II alpha (TOP2A) and minichromosome maintenance protein 2 (MCM2) has been considered to have tight association with high grade intraepithelial lesions. Materials and Methods: A total number of 54 SurePath cervical cytology specimens of patients previously interpreted as atypical squamous cells-undetermined significance (ASC-US), atypical squamous cells-cannot exclude high grade squamous intraepithelial lesion (ASC-H), low grade squamous intraepithelial lesion (LSIL), and high grade squamous intraepithelial lesion (HSIL) were included in our study. Results and Conclusions: ProEx C was positive in 14 of HSILs (100%), 3 of 19 LSILs (16%), 2 of 4 ASC-Hs, and none of ASC-USs (0%). The ProEx C test showed very intense nuclear staining in all cytologically abnormal cells. Further studies are indicated to evaluate the diagnostic role of ProEx C

Gençlerin anüler likenoid dermatiti: İki olgu sunumu ve literatürün gözden geçirilmesi

Annular lichenoid dermatitis of youth is a rare chronic dermatosis with an unknown cause, affecting both genders at an equal frequency. It is clinically characterized by a hypopigmented center and an erythematous border or hyperpigmented annular patches or plaques. The differential diagnosis includes annular dermatoses, such as tinea, erythema annulare centrifugum, erythema chronicum migrans, morphea, and mycosis fungoides. In this case report, we examined the clinical and histopathological features of two male patients aged 9 and 12 years with annular lichenoid dermatitis and presented their 3-year follow-up data while also reviewing the cases reported in the literature.Gençlerin anüler likenoid dermatiti, sebebi net bilinmeyen, nadir görülen, her iki cinsiyeti de eşit sıklıkta etkileyen, kronik seyirli bir dermatozdur. Klinik olarak ortası hipopigmente, etrafı eritematöz veya hiperpigmente anüler yama veya plaklarla karakterizedir. Ayırıcı tanısında tinea, eritem anüler sentrifigum, eritema kronikum migrans, morfea, mikozis fungoides (MF) gibi anüler dermatozlar yer alır. Burada anüler likenoid dermatitli 9 ve 12 yaşlarında iki erkek hastanın klinik ve histopatolojik özeliklerini irdeleyip ayırıcı tanıya giren hastalıkları vurgulayıp üç yıllık takiplerini sunarken literatürde bildirilmiş olguları da gözden geçirdik