Socket restoration by simple incision

Objectives: To ensure reconstruction of contracted eyesocket with the use of simple incision and appropriateconformer.Materials and Methods: A total 54 cases who appliedbetween 1991-2006 years, due to the complaint of notfitting the prosthesis were enrolled.Results: The mean follow up time was 72.8 (6-119)months. After simple incision 28 patients was able to fittheir prosthesis after first operation. This incision was repeatedtwo times in 7 patients and three times in 2 patients.We were unable to follow 7 patients with simpleincision. In 37 out of 47 patients the results were found tobe successful, in 12 patients other methods were used.Conclusion: In anophthalmic socket and postenucleationsocket syndrome, simple incision can be taken intoconsideration before deciding for an enhancement operation

Indications and Outcomes of Amniotic Membrane Transplantation

Objectives: To investigate the indications and outcomes of amniotic membrane transplantation (AMT). Materials and Methods: A total of 87 eyes who underwent amnion membrane transplantation in our clinic between February 2010 and April 2013 were included in this study. Mean follow-up period was 7.49±7.84 months (range 1-29 months). Amnion membrane defrosted at room temperature and washed three times with saline covered all over the cornea independent of the position and size of the lesion and was sutured to the peripheral cornea circumferentially by 10/0 monofilament suture. At the end of the operation, therapeutic contact lens was placed. All cases were evaluated with respect to duration of surface epithelial healing, visual acuity, presence of recurrence, and infection. Results: Forty-six of the 87 patients (52.8%) were men and 41 (47.1%) were women. The mean age was 57.02±19.74 years (range 31-89 years) in men and 66.69±16.56 years (range 8-88 years) in women. The indications were: ulcers in 27 eyes, keratitis in 24 eyes, topical anesthetic abuse in 10 eyes, bullous keratopathy in 7 eyes, conjunctival mass in 7 eyes, symblepharon in 3 eyes, chemical burns in 3 eyes, pterygium in 2 eyes, endophthalmitis in 2 eyes, dellen in 1 eye, and conjunctival laceration in 1 eye. After AMT, 12 patients required second AMT, and 2 cases required third AMT. 2 eyes were eviscerated, 1 eye was exenterated. At the final follow-up visit, except for patients who underwent evisceration and exenteration, improved visual acuity was observed in 45 of the 84 eyes (53.5%). The average of healing time was between 4 and 6 weeks. No infectious, inflammatory, immunologic, or toxic/allergic reactions related to AMT was observed. Conclusion: Amniotic membrane transplantation is a safe and effective technique in ocular surface diseases. (Turk J Ophthalmol 2014; 44: 123-

Formula Student csapat teljesítménymenedzsment-rendszerének kialakítása

A szakdolgozat célja egy teljesítménymenedzsment-rendszer kialakítása egy Formula Student csapat számára, figyelembe véve a motivációs tényezőket. Ez azért szükséges, mert a jelenlegi működési keretek nincsenek átláthatóan kiépítve, ill. problémák merülnek fel a teljesítménnyel és a motivációval kapcsolatban. A teljesítményértékelés során egyéni és csapat szinten átláthatóbbá válik a munkavégzés, tisztázhatóak az elvárások és a problémák, ösztönözhetők a tagok a fejlődésre és az aktivitásra

Effects of melatonin on Wi-Fi-induced oxidative stress in lens of rats

Introduction: Melatonin has been considered a potent antioxidant that detoxifies a variety of reactive oxygen species in many pathophysiological states of eye. The present study was designed to determine the effects of Wi-Fi exposure on the lens oxidant, antioxidant redox systems, as well as the possible protective effects of melatonin on the lens injury induced by electromagnetic radiation (EMR). Materials and Methods: Thirty-two rats were used in the current study and they were randomly divided into four equal groups as follows: First and second groups were cage-control and sham-control rats. Rats in third group were exposed to Wi-Fi (2.45 GHz) for duration of 60 min/day for 30 days. As in the third group, the fourth group was treated with melatonin. The one-hour exposure to irradiation in second, third and fourth took place at noon each day. Results: Lipid peroxidation levels in the lens were slightly higher in third (Wi-Fi) group than in cage and sham control groups although their concentrations were significantly (P < 0.05) decreased by melatonin supplementation. Glutathione peroxidase (GSH-Px) activity was significantly (P < 0.05) lower in Wi-Fi group than in cage and sham control groups although GSH-Px (P < 0.01) and reduced glutathione (P < 0.05) values were significantly higher in Wi-Fi + melatonin group than in Wi-Fi group. Conclusions: There are poor oxidative toxic effects of one hour of Wi-Fi exposure on the lens in the animals. However, melatonin supplementation in the lens seems to have protective effects on the oxidant system by modulation of GSH-Px activity

Involvement of bilateral lacrimal gland in systemic Hodgkin disease

Five percent (5%) of lacrimal gland tumors are originatedfrom lymphoid tissue. In one type of Hodgkin diseasewhich is abounding in lymphocytes, involvement of lacrimalgland is a rather rare entity.A 48 – year old woman who had swollen both eyelids,applied to department of oculoplasty in our clinic. At inspection,when eyelids were rotated, a mass was seenat the region which fits to bilateral lacrimal gland area.Magnetic resonance imaging of the orbita showed a welldemarcatedsoft tissue mass without invade adjacentstructure in the supero-lateral aspect of the bilateral orbit,occupying lacrimal gland. Lymphadenopathies in abdominal,cervical, inguinal, axillary regions have been found insystemic scanning. Biopsy of lacrimal gland and axillarylymphadenopahty were performed and histopathologicalexamination revealed the diagnosis as Hodgkin diseaseabounding in lymphocytes. The patient was underwentfour cure chemotherapy. Clinical and tomographic findingswere found to be regressed after treatment

Pachydermoperiostosis as a Rare Cause of Blepharoptosis

A 37-year-old male patient diagnosed with pachydermoperiostosis at another center came to our clinic to rectify his blepharoptosis. The physical examination of the patient revealed skeleton and skin symptoms typical for pachydermoperiostosis. There was thickening and extending horizontal length of the eyelids, an S-shaped deformity on the edges of the eyelids, and symmetric bilateral mechanical blepharoptosis. In order to treat the blepharoptosis, excision of the thickened skin and the orbicular muscle as well as levator aponeurosis surgery was performed. The esthetic result was satisfactory. Pachydermoperiostosis is a rare cause of blepharoptosis. Meibomius gland hyperplasia, increase of collagen substance in the dermis, mucin accumulation are reasons of thickening the eyelid and finally this causes the development of mecanical blepharoptosis. Even though many two or three phased surgical procedures can be applied to these cases, satisfactory results can be achieved with levator surgery and excision of the thickened skin and the orbicular muscle as well. (Turk J Ophthalmol 2014; 44: 416-8

Comparison of Cumulative Corticosteroid Doses for Critically Ill Patients with COVID-19

Introduction: Dexamethasone is the first medication that improved survival in patients with Coronavirus disease-2019 (COVID-19); however, the effects of corticosteroids with different cumulative doses on disease outcome must be elucidated. Our study aimed to compare clinical features, hospital mortality, and secondary infections in patients with COVID-19 receiving different cumulative doses of systemic corticosteroids. Materials and Methods: A retrospective, observational study was conducted on patients with COVID-19 admitted to intensive care unit between 21st March 2020 and 20th September 2020 to determine who did not receive systemic corticosteroids, who received low-to-moderate cumulative doses of corticosteroids as recommended by the RECOVERY trial [proposed 6 mg of dexamethasone (equivalent to 32 mg methylprednisolone)] for 10 days (total dose of ≤320 mg of methylprednisolone or equivalent doses of corticosteroids), and who received high cumulative doses of corticosteroids (total dose of >320 mg methylprednisolone equivalent). Results: Among 134 patients, 35 (26%) did not receive systemic corticosteroids, 34 (25%) received low-to-moderate cumulative doses of corticosteroids, and 65 (49%) received high cumulative doses of corticosteroids. Secondary bacterial (31.4% vs. 41.2% and 63.1%, p=0.006) and opportunistic infections (2.9% vs. 5.9% and 21.5%, p=0.011) were more frequently observed in the low-to-moderate- and high-dose corticosteroid groups compared with those in the no corticosteroid group. Hospital mortality was 20% in patients who did not receive steroids and 29.4% and 46.2% in patients who received low-to-moderate and high doses of corticosteroids, respectively (p=0.012). High cumulative doses of systemic corticosteroids were found to be the independent determinant for hospital mortality [Odds ratio (OR): 6.302 (1.856-21.394); p=0.003] and secondary infection [OR: 3.334 (1.313-8.496); p=0.011]. Conclusion: Comparison among patients administered with and without systemic corticosteroids revealed that high cumulative doses may be associated with adverse events in critically ill patients with COVID-19

Evaluation of Intranasal Ostium in External Dacryocystorhinostomy

Objective: The investigation of factors affecting the dimension and configuration of the intranasal ostium in successful external dacryocystorhinostomy (DCR). Material and Methods: Fifty-one patients were enrolled within this study. During operation, dimensions of bone window were measured. In the postoperative sixth month, changes in bone window size were evaluated using spiral paranasal tomography, and the intranasal ostium was examined with nasal endoscopy. Results: There were 19 patients who underwent DCR and 32 patients who underwent DCR+silicone tube intubations (SI). The mean bone window size was 214.37 mm2 during operation and 214.87 mm2 after six months. The mean intranasal ostium size was measured as 51.42 mm2 for patients who had undergone DCR and 28.66 mm2 for the DCR+SI cases. The endoscopic appearance of the ostium was observed as oval or round for the DCR cases and in slit form for the DCR+SI cases. A multiple logistic regression model showed that silicon tube intubation posed an 11 times greater risk for configuration distortion in the intranasal ostium (p=0.0079).Conclusion: Postoperative intranasal ostium size has a relation with the intraoperative bone window size. The difference of mean intranasal ostium sizes of DCR and DCR+SI cases was not statistically significant. However, because SI gives rise to ostium configuration by triggering fibrosis, it should not be carried out unless absolutely necessary

Association Between Mobile Phone Radiation Exposure and the Secretion of Melatonin and Cortisol, Two Markers of the Circadian System : A Review

The extremely important use of mobile phones in the world, at all ages of life, including children and adolescents, leads to significant exposure of these populations to electromagnetic waves of radiofrequency. The question, therefore, arises as to whether exposure to these radiofrequencies (RFs) could lead to deleterious effects on the body's biological systems and health. In the current article, we review the effects, in laboratory animals and humans, of exposure to RF on two hormones considered as endocrine markers: melatonin, a neurohormone produced by the pineal gland and cortisol, a glucocorticosteroid synthesized by the adrenal glands. These two hormones are also considered as markers of the circadian system. The literature search was performed using PubMed, Medline, Web of Sciences (ISI Web of Knowledge), Google Scholar, and EMF Portal. From this review on RF effects on cortisol and melatonin, it appears that scientific papers in the literature are conflicting, showing effects, no effects, or inconclusive data. This implies the need for additional research on higher numbers of subjects and with protocols perfectly controlled with follow‐up studies to better determine whether the chronic effect of RF on the biological functioning and health of users exists (or not). Bioelectromagnetics