Self-leadership and Growth Mindset as Mutually Supportive Determinants of Behaviors

Purpose: This article is focused on checking whether there is an interdependence between the levels of self-leadership and growth mindset presented by an individual and whether these factors affect the functioning of employees.Methodology: The respondents were an open group of 237 participants of different age, job seniority and position. The following questionnaires were used in the study: ASQL by Houghton, Dawley and DiLiello – to measure the level of self-leadership, and NNR by Godlewska-Werner – to measure the level of growth mindset.Findings: The results of the study show that self-leadership and growth mindset are factors that significantly affect each other. However, there are no relationships between the overall level of self-leadership and: age, sex,job seniority or holding managerial positions.Research and practical implications: Research can be important to management practice in team building processes as the level of selfleadership can be a relevant factor which promoted and shared among coworkers allows to create a more balanced, engaging work environment for managers and those they lead. Originality/value: The research conducted so far has focused on the analysis of the connections between growth mindset and leadership. This research shows that growth mindset also affects the level of selfleadership, and thus individuals’ attitude to aspects such as: making the effort, accepting feedback or the success of co-workers.Paper type: research pape

Rapid generation of molecular complexity under Pd(II) and Rh(III) catalysis

1. Enantioselective Pd(II)-Catalysed Nucleophilic Additions of 2- Alkylazaarenes The first project deals with enantio- and diastereoselective palladium(II)-catalysed nucleophilic additions of 2-alkylazaarenes to N-Boc imines and nitroalkenes. Under the optimised reaction conditions high levels of diastereo- and enantioselection of the addition products were achieved. Introduction of the electron-withdrawing group at the aryl ring of the substrate allows running the reaction under mild, experimentally convenient reaction conditions. The new described method allows the enantioselective synthesis of 2-(β-aminoalkyl)azaarenes, which are substructures found in drug candidates molecules for the treatment of type 2 diabetes and schizophrenia. 2. Synthesis of Spirocyclic Enones via Rh(III)-Catalysed C–H Functionalisation The second project describes the synthesis of spirocyclic enones by rhodium(III)- catalysed dearomatising oxidative annulation of 2-alkenylphenols with alkynes and 1,3-enynes. A good to high yield with great regioselectivity was obtained. The further synthetic utility of the product was also investigated and led to the formation of highly functionalised tetracycles via 1,6 conjugation addition reaction

Synthesis of spirocyclic enones by rhodium-catalyzed dearomatizing oxidative annulation of 2-alkenylphenols with alkynes and enynes

The dearomatizing oxidative annulation of 2-alkenylphenols with alkynes and enynes proceeds with high yields and regioselectivities under Rh(III) catalysis. These reactions are successful using Cu(OAc)2 or air as the stoichiometric oxidant, and provide spirocyclic enones, the basic ring system of which appears in several natural products. Application of this process to the preparation of a highly functionalized tetracycle is also demonstrated

Practical aspects of genetic identification of hallucinogenic and other poisonous mushrooms for clinical and forensic purposes

Aim To assess the usefulness of a DNA-based method for identifying mushroom species for application in forensic laboratory practice. Methods Two hundred twenty-one samples of clinical forensic material (dried mushrooms, food remains, stomach contents, feces, etc) were analyzed. ITS2 region of nuclear ribosomal DNA (nrDNA) was sequenced and the sequences were compared with reference sequences collected from the National Center for Biotechnology Information gene bank (GenBank). Sporological identification of mushrooms was also performed for 57 samples of clinical material. Results Of 221 samples, positive sequencing results were obtained for 152 (69%). The highest percentage of positive results was obtained for samples of dried mushrooms (96%) and food remains (91%). Comparison with GenBank sequences enabled identification of all samples at least at the genus level. Most samples (90%) were identified at the level of species or a group of closely related species. Sporological and molecular identification were consistent at the level of species or genus for 30% of analyzed samples. Conclusion Molecular analysis identified a larger number of species than sporological method. It proved to be suitable for analysis of evidential material (dried hallucinogenic mushrooms) in forensic genetic laboratories as well as to complement classical methods in the analysis of clinical materia

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2-Alkylazaarenes to N-Boc Imines and Nitroalkenes

A chiral Pd(II)–bis(oxazoline) complex was found to be highly effective in promoting the first direct diastereo- and enantioselective addition of alkylazaarenes to N-Boc aldimines and nitroalkenes under mild conditions. Deprotection of Boc-protected products proceeded readily to provide amines in high yields

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2‑Alkylazaarenes to <i>N</i>‑Boc Imines and Nitroalkenes

A chiral Pd­(II)–bis­(oxazoline) complex was found to be highly effective in promoting the first direct diastereo- and enantioselective addition of alkyl­aza­arenes to <i>N</i>-Boc aldimines and nitroalkenes under mild conditions. Deprotection of Boc-protected products proceeded readily to provide amines in high yields

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2‑Alkylazaarenes to <i>N</i>‑Boc Imines and Nitroalkenes

A chiral Pd­(II)–bis­(oxazoline) complex was found to be highly effective in promoting the first direct diastereo- and enantioselective addition of alkyl­aza­arenes to <i>N</i>-Boc aldimines and nitroalkenes under mild conditions. Deprotection of Boc-protected products proceeded readily to provide amines in high yields

Diastereo- and Enantioselective Pd(II)-Catalyzed Additions of 2‑Alkylazaarenes to <i>N</i>‑Boc Imines and Nitroalkenes

A chiral Pd­(II)–bis­(oxazoline) complex was found to be highly effective in promoting the first direct diastereo- and enantioselective addition of alkyl­aza­arenes to <i>N</i>-Boc aldimines and nitroalkenes under mild conditions. Deprotection of Boc-protected products proceeded readily to provide amines in high yields

Low-cost, programmable infusion pump with bolus mode for in-vivo imaging

Syringe pumps are routinely used in biomedical imaging laboratories for delivering contrast agents and either infusing or injecting a precise amount of liquids. Commercial syringe pumps that are developed by specialized companies are expensive and only have standard functions, which often do not meet the requirements of individual experiments. In this paper, we demonstrate an open-source single syringe pump with the possibility of adapting to the needs of a researcher. The device that was designed, is controlled by an Arduino Leonardo, along with the stepper motor driver. For sending commands and receiving the current plunger position, a C# software was developed with serial communication via USB. Additionally, the 3D models were made in a universal way, which allows for the use of any syringe size. An example of the application of the syringe pump for biomedical applications was demonstrated using electron resonance imaging (ERI). The single syringe pump tests were demonstrated by simulating the filling of a particular volume inside the resonator. This example reflects the clearance process after an intravascular (I.V) drug administration in the murine model. The experiments were performed on an ERI TM 600 tomograph. The results confirmed that the designed syringe pump allowed for controlling the infusion speed and injected volume. Moreover, we present a user-friendly and opensource graphical interface that is a low-cost alternative for commercial devices