522 research outputs found
Dynamics of the BCS-BEC crossover in a degenerate Fermi gas
We study the short-time dynamics of a degenerate Fermi gas positioned near a
Feshbach resonance following an abrupt jump in the atomic interaction resulting
from a change of external magnetic field. We investigate the dynamics of the
condensate order parameter and pair wavefunction for a range of field
strengths. When the abrupt jump is sufficient to span the BCS to BEC crossover,
we show that the rigidity of the momentum distribution precludes any
atom-molecule oscillations in the entrance channel dominated resonances
observed in the 40K and 6Li. Focusing on material parameters tailored to the
40K Feshbach resonance system at 202.1 gauss, we comment on the integrity of
the fast sweet projection technique as a vehicle to explore the condensed phase
in the crossover regionComment: 5 pages, 4 figure
Comparison of Flow-Through Cell and Paddle Methods for Testing Vaginal Tablets Containing a Poorly Water-Soluble Drug
Purpose: To evaluate the usefulness of the flow-through cell apparatus for testing commercial vaginal tablets containing poorly water-soluble clotrimazole.Methods: The effect of experimental conditions (type of dissolution medium, flow rate and positioning of the tablet) on the dissolution profile of clotrimazole were examined and optimal parameters for conducting the experiments were determined. The amount of drug released was analyzed by high performance chromatography (HPLC) at 210 nm. The usefulness of the flow-through cell apparatus was compared to FDA recommended paddle apparatus.Results: Using acetate buffer pH 5.2 containing 1 % SDS, both methods gave different dissolution profiles. The paddle apparatus tended to give faster rate of dissolution (approx. 88.5 % during the first 20 min of the experiment), which was probably caused by higher agitation and greater surface area of the drug-dissolution medium in a vessel. In the flow-through cell method, total drug release was definitely slower and was observed after 2 to 5 h; at a flow rate of 16 ml/min, more than 80 % of the drug dissolved after 30 min of the test. It was noticed that raising the flow rate of the dissolution medium caused significantly higher drug release.Conclusion: The results demonstrate that the flow-through cell method is reproducible and can be successfully used for evaluating in vitro dissolution of clotrimazole from non-modified release tablets. The slower rate of dissolution obtained in the flow-through cell method would help to distinguish between different formulations.Keywords: Dissolution test, Flow-through cell method, Paddle method, Clotrimazol
Spontaneous rotating vortex rings in a parametrically driven polariton fluid
We present the theoretical prediction of spontaneous rotating vortex rings in
a parametrically driven quantum fluid of polaritons -- coherent superpositions
of coupled quantum well excitons and microcavity photons. These rings arise not
only in the absence of any rotating drive, but also in the absence of a
trapping potential, in a model known to map quantitatively to experiments. We
begin by proposing a novel parametric pumping scheme for polaritons, with
circular symmetry and radial currents, and characterize the resulting
nonequilibrium condensate. We show that the system is unstable to spontaneous
breaking of circular symmetry via a modulational instability, following which a
vortex ring with large net angular momentum emerges, rotating in one of two
topologically distinct states. Such rings are robust and carry distinctive
experimental signatures, and so they could find applications in the new
generation of polaritonic devices.Comment: 6 pages, 4 figure
Trapping Long-Lifetime Excitons in a Two-Dimensional Harmonic Potential
We report an important step forward for the goal of unambiguous observation
of Bose-Einstein condensation of excitons in semiconductors. We have
demonstrated a system in which excitons live for microseconds, much longer than
their thermalization time, move over distances of hundreds of microns, and can
be trapped in a harmonic potential exactly analous to the traps for atomic
condensates. We also report recent results of a new method for observing
evidence of Bose-Einstein condensation, by angular resolution of the emitted
luminescence.Comment: Invited paper for International Conference on Spontaneous Coherence
in Excitonic Systems, Seven Springs, PA, May 2004. To appear in Solid State
Communication
Properties of the signal mode in the polariton optical parametric oscillator regime
Theoretical analyses of the polariton optical parametric oscillator (OPO) regime often rely on a mean-field approach based on the complex Gross-Pitaevskii equations in a three-mode approximation, where only three momentum states, the signal, pump, and idler, are assumed to be significantly occupied. This approximation, however, lacks a constraint to uniquely determine the signal and idler momenta. In contrast, multimode numerical simulations and experiments show a unique momentum structure for the OPO states. In this work we show that an estimate for the signal momentum chosen by the system can be found from a simple analysis of the pump-only configuration. We use this estimate to investigate how the chosen signal momentum depends on the properties of the drive
Polariton condensation and lasing in optical microcavities - the decoherence driven crossover
We explore the behaviour of a system which consists of a photon mode dipole
coupled to a medium of two-level oscillators in a microcavity in the presence
of decoherence. We consider two types of decoherence processes which are
analogous to magnetic and non-magnetic impurities in superconductors. We study
different phases of this system as the decoherence strength and the excitation
density is changed. For a low decoherence we obtain a polariton condensate with
comparable excitonic and photonic parts at low densities and a BCS-like state
with bigger photon component due to the fermionic phase space filling effect at
high densities. In both cases there is a large gap in the density of states. As
the decoherence is increased the gap is broadened and suppressed, resulting in
a gapless condensate and finally a suppression of the coherence in a low
density regime and a laser at high density limit. A crossover between these
regimes is studied in a self-consistent way analogous to the Abrikosov and
Gor'kov theory of gapless superconductivity.Comment: 17 pages, 8 figures, submitted to PR
Coordination and organometallic precursors of group 10 and 11 Focused electron beam induced deposition of metals and insight gained from chemical vapour deposition, atomic layer deposition, and fundamental surface and gas phase studies
Nanostructured materials made from group 10 Ni, Pd, Pt and group 11 Cu, Ag, Au elements have outstanding technological relevance in microelectronics, nano optics, catalysis, and energy conversion. Processes that allow for the easy and reliable fabrication of such nanostructures are heavily sought after. Focused electron beam induced deposition FEBID is the only direct write technique that can fabricate nanostructures with arbitrary shape and dimensions down to the sub 10 nm regime. However, the complex chemistry of FEBID involving electron induced dissociation processes of metalorganic precursors molecules, surface kinetics, and thermal effects is poorly understood and far from being optimized. Here, we review in a comparative manner the performance and the underlying chemical reactions of surface deposition processes, namely, chemical vapour deposition CVD , atomic layer deposition ALD , and FEBID itself. The knowledge gained in CVD and ALD as related surface deposition techniques will help us to understand the spatially selective chemistry occurring in FEBID. Fundamental surface and gas phase studies provide insight to electron induced chemistry and desorption of precursor fragments. Specific emphasis is put on the type of the ligands and their different behaviour under thermal, surface related, and electron induced processes. The comprehensive overview of the current state of FEBID for group 10 and 11 metals includes reactive environments and purification approaches as these may provide valuable information on the design of novel precursors. The evaluation of the precursor and process performance is extended to include W, Co, Fe, Ru, Rh, and Ir to represent a general guide towards future developments in FEBID. These may not only rely on the design of novel compounds but also on optimized deposition strategies inspired by ALD and CV
Yield criteria for glaciotectonically deformed deposits
Most glaciotectonically deformed deposits, including varved clays and glacial tills, are characterised by cracks and fissures. This paper presents a method for describing the yield criteria for glacitectonically deformed cohesive deposits using a model of cracked geomaterial with isotropic or anisotropic matrix. The general representation of the limit conditions for anisotropic materials in plane-strain is used to determine the yield criterion. The yield criterion represents a convex, piece-wise surface in the three-dimensional stress space revealing explicitly global, plastic properties of the materials considered. An example of using proposed yield criteria to solve a bearing capacity problem of a strip foundation constructed on a glaciotectonically cracked layer is presented. The lower and upper-bound estimates of limit loads on the strip footing are given. The limit state analysis presented in this paper can be used to solve many other geotechnical engineering problems, for example, the stability of slopes and reinforced walls or the bearing capacity of pile foundations
The effect of tumour necrosis factor-α (TNF-α) muteins on human neutrophils in vitro
Tumour necrosis factor-α (TNF-α) has been implicated as an important inflammatory mediator. In vitro, TNF-α is reported to activate human polymorphonuclear neutrophils (PMN), inducing responses such as phagocytic activity, degranulation and oxidative metabolism. Biological responses to TNF-α are initiated by its binding to specific cell surface receptors, and various studies have shown that the major TNF receptor species on PMN is the 75 kDa receptor. To verify the suggestion that the receptor binding domain includes the region close to the N-terminus of the TNF-α molecule, four TNF-α derivatives termed muteins were constructed, using a synthetic cDNA fragment substituting the N-terminal 3–7 selected hydrophilic or hydrophobic amino acids in the original TNF-α genomic DNA. Binding of muteins to PMN was assessed using monoclonal antibodies recognizing either the 55 kDa (p55) or the 75 kDa (p75) TNF receptor subtypes. Blocking by muteins of anti-p75 antibody binding to PMN was as expected from their N-terminal amino acid composition and hydrophilic properties. Hydrophilic muteins competed well with anti-TNF receptor antibodies for binding to the p75 receptor. In contrast, hydrophobic muteins were unable to block anti-p75 binding. Similarly, degranulation, chemiluminescence or enhancement of the PMN response to specific stimuli by the muteins correlated with the hydrophilic properties of the muteins. The significance of these observations in relation to the molecular structure of TNF-α is discussed
Many-body physics of a quantum fluid of exciton-polaritons in a semiconductor microcavity
Some recent results concerning nonlinear optics in semiconductor
microcavities are reviewed from the point of view of the many-body physics of
an interacting photon gas. Analogies with systems of cold atoms at thermal
equilibrium are drawn, and the peculiar behaviours due to the non-equilibrium
regime pointed out. The richness of the predicted behaviours shows the
potentialities of optical systems for the study of the physics of quantum
fluids.Comment: Proceedings of QFS2006 conference to appear on JLT
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