(Penta­fluoro­propionato-κO)tetra­kis­(trimethyl­phosphine oxide-κO)copper(II) penta­fluoro­propionate

The title compound, [Cu(C3F5O2)(C3H9OP)4](C3F5O2), comprises a cationic CuII complex and a disordered penta­fluoro­propionate counter-ion. The metal atom has a distorted square-pyramidal coordination environment formed by four O atoms originating from trimethyl­phosphine oxide mol­ecules and the remaining one belonging to the monodentate penta­fluoro­propionate anion, which is situated in the basal plane of the pyramid. The mol­ecules are held together in the crystal by a net of weak C—H⋯O and C—H⋯F hydrogen bonds. The counter anion is disordered over two sets of sites in a 0.629 (5):0.371 (5) ratio

Non-equilibrium quantum condensation in an incoherently pumped dissipative system

We study spontaneous quantum coherence in an out of equilibrium system, coupled to multiple baths describing pumping and decay. For a range of parameters describing coupling to, and occupation of the baths, a stable steady-state condensed solution exists. The presence of pumping and decay significantly modifies the spectra of phase fluctuations, leading to correlation functions that differ both from an isolated condensate and from a laser.Comment: 5 pages, 2 eps figure

Thermodynamics and Excitations of Condensed Polaritons in Disordered Microcavities

We study the thermodynamic condensation of microcavity polaritons using a realistic model of disorder in semiconductor quantum wells. This approach correctly describes the polariton inhomogeneous broadening in the low density limit, and treats scattering by disorder to all orders in the condensed regime. While the weak disorder changes the thermodynamic properties of the transition little, the effects of disorder in the condensed state are prominent in the excitations and can be seen in resonant Rayleigh scattering.Comment: 5 pages, 3 eps figures (published version

POLISH TOWNS AND THE CHANGES IN THEIR AREAS AND POPULATION DENSITIES

DOI: 10.2478 Available on-line at: http://www.bulletinofgeography.umk.pl http://versita.com/bgssThis article presents the spatial and population density changes in Polish towns in the years 1960–2003. The assumed time frame allowed identifying area changes for a complete set of towns in different socio-economic conditions: the period of intense industrialisation, the economic crisis of the 1980s, the period of economic transition and finally in the years of a market economy. The investigation revealed that the trend shown by changes and the size of a town as measured by the number of its population are distinctly interrelated. It also demonstrated a much stronger dynamics of changes in the first subperiod, i.e. years 1960–1985, followed by a phase of relative stabilization (compared with the previous period) after the year 1980 (mainly of the spatial changes). Moreover, change intensity and change trends observed for the urban areas and population densities vary considerably in terms of space

A comparison of the Antileukaemic Effects of Recombinant Human Tumour Necrosis Factor-α and its Muteins on Leukaemia L1210 and Leukaemia P388 in Mice

We investigated the influence of recombinant human tumour necrosis factor alpha (TNF-α) and its derivatives termed muteins III, V, VI—in which the first 3 to 7 amino acids of native TNF-α have been replaced—on the survival time of mice inoculated with leukaemia L1210 or leukaemia P338. TNF-α prolonged the survival of mice with leukaemia L1210 but did not have any therapeutic activity in leukaemia P388-bearing mice. Muteins-treated mice with leukaemia P388 lived longer than animals receiving TNF-α, while those inoculated with leukaemia L1210 did not show any significant prolongation of life compared with the TNF-α treated group. The results presented in this report indicate that the antileukaemic activity of TNF-α is governed at least in part by the nature of the N-terminal amino acids

Vortex and half-vortex dynamics in a spinor quantum fluid of interacting polaritons

Spinorial or multi-component Bose-Einstein condensates may sustain fractional quanta of circulation, vorticant topological excitations with half integer windings of phase and polarization. Matter-light quantum fluids, such as microcavity polaritons, represent a unique test bed for realising strongly interacting and out-of-equilibrium condensates. The direct access to the phase of their wavefunction enables us to pursue the quest of whether half vortices ---rather than full integer vortices--- are the fundamental topological excitations of a spinor polariton fluid. Here, we are able to directly generate by resonant pulsed excitations, a polariton fluid carrying either the half or full vortex states as initial condition, and to follow their coherent evolution using ultrafast holography. Surprisingly we observe a rich phenomenology that shows a stable evolution of a phase singularity in a single component as well as in the full vortex state, spiraling, splitting and branching of the initial cores under different regimes and the proliferation of many vortex anti-vortex pairs in self generated circular ripples. This allows us to devise the interplay of nonlinearity and sample disorder in shaping the fluid and driving the phase singularities dynamicsComment: New version complete with revised modelization, discussion and added material. 8 pages, 7 figures. Supplementary videos: https://drive.google.com/folderview?id=0B0QCllnLqdyBfmc2ai0yVF9fa2g2VnZodGUwemVkLThBb3BoOVRKRDJMS2dUdjlZdkRTQk

Conventional character of the BCS-BEC cross-over in ultra-cold gases of 40K

We use the standard fermionic and boson-fermion Hamiltonians to study the BCS-BEC cross-over near the 202 G resonance in a two-component mixture of fermionic 40K atoms employed in the experiment of C.A. Regal et al., Phys. Rev. Lett. 92, 040403 (2004). Our mean-field analysis of many-body equilibrium quantities shows virtually no differences between the predictions of the two approaches, provided they are both implemented in a manner that properly includes the effect of the highest excited bound state of the background scattering potential, rather than just the magnetic-field dependence of the scattering length. Consequently, we rule out the macroscopic occupation of the molecular field as a mechanism behind the fermionic pair condensation and show that the BCS-BEC cross-over in ultra-cold 40K gases can be analysed and understood on the same basis as in the conventional systems of solid state physics.Comment: 16 pages, 10 eps figures; final versio

The effect of enzyme replacement therapy on clinical outcomes in paediatric patients with Fabry disease – A systematic literature review by a European panel of experts

BACKGROUND: Fabry disease is caused by a deficiency of the lysosomal enzyme α-galactosidase, resulting in progressive accumulation of globotriaosylceramide (GL-3). The disease can manifest early during childhood and adolescence. Enzyme replacement therapy (ERT) with recombinant human α-galactosidase is the first specific treatment for Fabry disease and has been available in Europe since 2001. This paper presents the findings of a systematic literature review of clinical outcomes with ERT in paediatric patients with Fabry disease. METHODS: A comprehensive systematic review of published literature on ERT in Fabry disease was conducted in January 2017. The literature analysis included all original articles reporting outcomes of ERT in paediatric patients. RESULTS: Treatment-related outcomes in the paediatric population were reported in six publications derived from open-label clinical trials and in 10 publications derived from observational or registry-based studies. ERT was shown to significantly reduce plasma and urine GL-3 levels in paediatric patients with Fabry disease. The effect of ERT on GL-3 clearance from renal podocytes appeared to be agalsidase dose-dependent. ERT relieved pain and improved gastrointestinal symptoms and quality of life. CONCLUSIONS: Based on the published literature, the use of ERT in paediatric patients can significantly clear GL-3 accumulation, ameliorate the early symptoms of Fabry disease, and improve quality of life. Treatment with ERT in paediatric patients with Fabry disease may be important to prevent further disease progression and overt organ damage

Collective coherence in planar semiconductor microcavities

Semiconductor microcavities, in which strong coupling of excitons to confined photon modes leads to the formation of exciton-polariton modes, have increasingly become a focus for the study of spontaneous coherence, lasing, and condensation in solid state systems. This review discusses the significant experimental progress to date, the phenomena associated with coherence which have been observed, and also discusses in some detail the different theoretical models that have been used to study such systems. We consider both the case of non-resonant pumping, in which coherence may spontaneously arise, and the related topics of resonant pumping, and the optical parametric oscillator.Comment: 46 pages, 12 figure

EVALUATION OF CONDITIONS CONCERNING THE DEVELOPMENT OF TOURISM. INVESTIGATION INTO THE BASIN OF THE PARSĘTA RIVER

DOI: 10.2478/v10089-008-0021-7 Available on-line at: http://www.bulletinofgeography.umk.pl http://versita.com/bgssThe article presents the results of multidimensional evaluation of conditions concerning the development of tourism in rural areas of Parsęta basin. For the purpose the synthetic measure has been applied in reference to 27 variables divided into two groups: suitable for tourism or investing. Having conducted the analysis of the selected variables, the investigated area was divided into three regions: the seaside at the North with very good conditions for the development of the touristic function as its core function, the central region, highly diversified with only moderate touristic capabilities, and finally the southern region, the lake district, with adequate features for the development of tourism