253 research outputs found

    Production Technology and Competitiveness In the Hungarian Manufacturing Industry

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    Following the big transformations of the 1990s, enterprise structure and technological level seem to have become stabilised in Hungary. Under these circumstances it is especially interesting to identify the elements responsible for competitiveness in general, and the role technology plays in development in particular, according to managers experienced in production and marketing. This empirical study – based on in-depth interviews and field research – summarises characteristics of the technological level in the sectors examined, role of technology and labour in production, effects of foreign direct investment, relations between competition and firm-level factors determining competitiveness, and concludes by summing up those most frequently mentioned proposals that should be incorporated into economic policy according to managers. Main findings indicate that more qualified, more intensive and cheaper labour can be substituted for high technology. The competitiveness of an enterprise is not determined by technology alone, but rather by a combination of technology, the parameters of available labour and the costs of investment increasing productivity. The insufficiency of inter-company relations, together with a shortage of available assets necessary for investment constitute the major threat undermining the competitiveness of enterprises in present-day Hungary

    Influence of copper on nickel-based catalysts in the conversion of glycerol

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    The catalytic transformation of glycerol to value-added compounds was investigated over bimetallic Ni-Cu/gamma-Al2O3 catalysts with Ni/Cu atomic ratios of 8/1, 4/1, 2/1, 1/1, 1/2, 1/4, and 1/8. XPS analysis revealed that the surface composition of the catalyst exhibited progressive enrichment of Cu as its content in the catalyst increased. H-2-chemisorption indicated that the total number of exposed Ni atoms decreased as the Cu content increased. As a result, deep hydrogenolysis to produce CH4 was inhibited by the addition of Cu to the Ni catalyst, yielding higher selectivity toward the dehydration products of glycerol such as hydroxyacetone.; FTIR spectra of adsorbed CO reveal that Cu asserts both geometric and electronic effects on the adsorption properties of Ni. The geometrical effect is visualized by the progressive disappearance of the bridge bound adsorbed CO on metallic Ni by the incorporation of Cu. This suggests that the deep hydrogenolysis of glycerol to CH4 formation requires an ensemble of adjacent active Ni atoms. The electronic effect of Cu on Ni is indicated by the red shift of the IR peak of adsorbed CO as the Cu content increases. The electronic interaction between Cu and Ni species was also substantiated by XANES results. HTREM revealed metal particles very well distributed on the support with particle size of 1.5 to 5 nm. The Ni Cu samples were not a total intermetallic alloys. (C) 2014 Elsevier B.V. All rights reserved.Postprint (published version

    Catches of Euxoa tritici in pheromone traps for Anarsia lineatella are due to the presence of (Z)-5-decenyl acetate as an impurity

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    Traps baited with the synthetic pheromone of Anarsia lineatella Zeller (Lepidoptera: Gelechiidae) frequently captured also Euxoa tritici L. males (Lepidoptera: Noctuidae) in field tests in Hungary. As (E)-monounsaturated compounds are uncommon among sex attractants or pheromone components of Noctuidae, it was hypothesized that the Euxoa catches may have been due to impurities of the (Z) isomer in synthetic (E)-5-decenyl acetate, which is the major component in the pheromone lure of A. lineatella. Traps baited with synthetic (Z)-5-decenyl acetate captured large numbers of E. tritici, and the compound showed a clear dose–response effect. Reanalysis of the synthetic batch of (E)-5-decenyl acetate used in preparation of the A. lineatella lure showed the presence of 10% of the (Z) isomer. Traps baited with synthetic (Z)-5-decenyl acetate can be used in the future for detection and monitoring purposes of E. tritici, a widely distributed pest of cereals and other field crops. The compound also showed attraction of Euxoa seliginis Duponche

    The 6 May 1976 Friuli earthquake: re-evaluating and consolidating

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    The aim of this paper is to propose the creation, in terms of European Macroseismic Scale (EMS-98), of the entire macroseismic fi eld of the 6 May 1976 Friuli earthquake. Only forty odd years have passed, and nothwithsatnding that there is a huge quantity of existing data, it was still disturbing to fi nd that much of the original data are missing and probably lost forever Efforts have therefore been made to fi nd additional and still unknown primary data. For the majority of the collected national data sets, a reevaluation was then possible. This study presents the comprehensive macroseismic data set for 14 European countries. It is, to our knowledge, one of the largest European data sets, consisting of 3423 intensity data points (IDPs). The earthquake was felt from Rome to the Baltic Sea, and from Belgium to Warsaw. The maximum intensity 10 EMS-98 was reached in eight localities in Friuli (Italy). Compared to previous studies, the Imax values have changed from country to country, in some cases being lowered due to methodological differences, but in the case of three among the most hit countries, Imax is now higher than in the previous studies, mainly due to the new data.Published417-4444T. Sismicità dell'ItaliaJCR Journa

    Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells

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    BACKGROUND: Diabetes mellitus is linked to pancreatic cancer. We hypothesized a role for pancreatic stellate cells (PSC) in the hyperglycemia induced deterioration of pancreatic cancer and therefore studied two human cell lines (RLT-PSC, T3M4) in hyperglycemic environment. METHODOLOGY/PRINCIPAL FINDINGS: The effect of chronic hyperglycemia (CHG) on PSCs was studied using mRNA expression array with real-time PCR validation and bioinformatic pathway analysis, and confirmatory protein studies. The stress fiber formation (IC: αSMA) indicated that PSCs tend to transdifferentiate to a myofibroblast-like state after exposure to CHG. The phosphorylation of p38 and ERK1/2 was increased with a consecutive upregulation of CDC25, SP1, cFOS and p21, and with downregulation of PPARγ after PSCs were exposed to chronic hyperglycemia. CXCL12 levels increased significantly in PSC supernatant after CHG exposure independently from TGF-β1 treatment (3.09-fold with a 2.73-fold without TGF-β1, p<0.05). The upregualtion of the SP1 transcription factor in PSCs after CHG exposure may be implicated in the increased CXCL12 and IGFBP2 production. In cancer cells, hyperglycemia induced an increased expression of CXCR4, a CXCL12 receptor that was also induced by PSC's conditioned medium. The receptor-ligand interaction increased the phosphorylation of ERK1/2 and p38 resulting in activation of MAP kinase pathway, one of the most powerful stimuli for cell proliferation. Certainly, conditioned medium of PSC increased pancreatic cancer cell proliferation and this effect could be partially inhibited by a CXCR4 inhibitor. As the PSC conditioned medium (normal glucose concentration) increased the ERK1/2 and p38 phosphorylation, we concluded that PSCs produce other factor(s) that influence(s) pancreatic cancer behaviour. CONCLUSIONS: Hyperglycemia induces increased CXCL12 production by the PSCs, and its receptor, CXCR4 on cancer cells. The ligand-receptor interaction activates MAP kinase signaling that causes increased cancer cell proliferation and migration

    Odderon Exchange from Elastic Scattering Differences between pp and pp^{-} Data at 1.96 TeV and from pp Forward Scattering Measurements

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    We describe an analysis comparing the p¯p elastic cross section as measured by the D0 Collaboration at a center-of-mass energy of 1.96 TeV to that in pp collisions as measured by the TOTEM Collaboration at 2.76, 7, 8, and 13 TeV using a model-independent approach. The TOTEM crosssections, extrapolated to a center-of-mass energy of √s=1.96  TeV, are compared with the D0 measurement in the region of the diffractive minimum and the second maximum of the pp cross section. The two data sets disagree at the 3.4σ level and thus provide evidence for the t-channel exchange of a colorless, C-odd gluonic compound, also known as the odderon. We combine these results with a TOTEM analysis of the same C-odd exchange based on the total cross section and the ratio of the real to imaginary parts of the forward elastic strong interaction scatteringamplitude in pp scattering for which the significance is between 3.4σ and 4.6σ. The combined significance is larger than 5σ and is interpreted as the first observation of the exchange of a colorless, C-odd gluonic compound
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