27 research outputs found
Organizational Justice, Parental Control And Team Commitment And Their Impacts On Strategic Performance
Penyelidikan ini menguji perhubungan di antara persepsi berkaitan kerja
(keadilan prosedur, keadilan pengagihan, dan kawalan strategik firma induk),
sikap (komitmen organisasi pada pelbagai pihak dan komitmen menjalankan
strategi), hasil gelagat (pencapaian organisasi dalam usahasama
antarabangsa).
The present research examines relationships among work-related perceptions
in term of procedural justice, distributive justice, and parental control, attitude
(organizational commitment to multiple parties and team’s commitment to
implementing strategy) and behavioral outcomes (organizational performance)
in IJV organization
Organizational Justice, Parental Control And Team Commitment And Their Impacts On Strategic Performance [HD6971.3. S995 2007 f rb].
Penyelidikan ini menguji perhubungan di antara persepsi berkaitan kerja (keadilan prosedur, keadilan pengagihan, dan kawalan strategik firma induk), sikap (komitmen organisasi pada pelbagai pihak dan komitmen menjalankan strategi), hasil gelagat (pencapaian organisasi dalam usahasama antarabangsa).
The present research examines relationships among work-related perceptions in term of procedural justice, distributive justice, and parental control, attitude (organizational commitment to multiple parties and team’s commitment to implementing strategy) and behavioral outcomes (organizational performance) in IJV organizatio
IMPLEMENTASI PROGRAM LAYANAN ADMINISTRASI KEPENDUDUKAN BERBASIS KEWENANGAN DESA DI DINAS KEPENDUDUKAN DAN CATATAN SIPIL KABUPATEN BANTAENG
This study purposed to determine the implementation of the village authority-based administrative service program based on program indicators, implementing organizations and target groups as well as supporting and inhibiting factors in its implementation at the Population and Civil Registration Office of Bantaeng Regency. This study used a qualitative descriptive type of research, to provide an overview of the implementation of village authority-based administrative services. The data analysis technique used data reduction, data presentation and conclusion. Then the data collection techniques used observation, interviews and documentation studies. The results of the study indicated that (a) the program, the village authority-based administrative service program had a clear objective, namely to make the administration of population administration closer, faster and the community no longer incured costs; (b) the implementing organization, the ability of the koordukcapil in providing population administration services in the village was good because it provided a quick response when there were people who took care of the authority-based administrative services; and (c) the target group were all village communities in Bantaeng Regency
A Preformulation of a Water Soluble Furosemide Dosage Form
Solid dispersion system of water-insoluble furosemide in polyvinylpirolidon (PVP) was prepared by a solvent method in various ratios of 1 : 1, 1 : 3, 1 : 5, 1 : 7 and 1 : 9 of the drug and PVP, respectively in order to improve furosemide solubility and dissolution. The improvement of furosemide solubility was studied by a solubility method in a shaking waterbath. The solubility test showed that various concentrations of PVP and temperature gave statistically significant increased of furosemida solubility (P < 0,05). The dissolution study of furosemide solid dispersion system was done using a dissolution tester at the rotation rate of 50 rpm. Furosemide concentration released was determined spectrophotometrically using a UV spectrofometer. This test showed a significant increased of furosemida solubility (P < 0,05), but with a prolonged of releasing time.Key Word : solid dispersion, solubility, dissolution, bioavailability
A COMPARATIVE BIOAVAILABILITY OF FUROSEMIDE IN SOLID DISPERSIONS FORMS
Furosemide is a poorly soluble diuretic drug, the solubility of which can be enhanced by solid dispersion with polyvinylpirolidon (PVP). The solid dispersion system was prepared by a solvent method in various ratios of 1 : 5 and 1 : 7 of the drug and PVP, respectively, in order to improve furosemide bioavailability. The bioavailability of furosemide - PVP solid dispersion was compared with pure furosemide (control) and Lasix (reference). The study was done in a cross over design with a single-dose peroral that administered to the white male rabbits (n = 6). Furosemide blood levels were determined spectrofluorometrically by an extraction method. The area under the blood concentration-time curve AUC0 - , peak blood concentration Cmax and time to reach peak blood concentration Tmax were used to compare their bioavailabilities. The solid dispersion systems produced a higher extent of bioavailability than pure furosemide (P < 0,05). On the contrary, no statistically significant difference about the extent of bioavailability between solid dispersion and Lasix (P > 0,05). Finally, furosemide – PVP solid dispersion (1 : 7) was the best formulation with the highest extent of bioavailability and bioequivalence with the Lasix formula.Key Word : Solid dispersion, solubility, dissolution, bioavailability, furosemide
Preformulasi Sediaan Furoseivhda Mudah Larut: A Preformulation of a Water Soluble Furosemide Dosage Form
Sistem dispersi padat furosemida yang sukar larut dalam air dan polivinilpirolidon disiapkan melalui metode pelarut dengan perbandingan 1 : 11 : 31 : 51 : 7 dan 1 : 9 dalam upaya meningkatkan kelarutan dan disolusi furosemida. Peningkatan kelarutan furosemida dilakukan dengan metode kelarutan menggunakan shaking waterbath. Uji kelarutan memperlihatkan bahwa PVP dengan berbagai kadar dan pada suhu yang berbeda meningkatkan kelarutan furosemida secara bermakna (P < 0,05). .
Uji disolusi sistem dispersi padat furosemida dilakukan menggunakan alat disolusi dengan kecepatan putar 50 rpm. Kadar furosemida terlarut ditentukan secara spektrofotometri UV. Uji ini memperlihatkan peningkatan jumlah furosemida yang terlarut secara bennakna (P < 0,05), tetapi tedadi penundaan waktu pelepasan awal.
!Cab\u27 Kunci : dispersi padat, kelarutan, disolusi, furosemida.
ABSTRACT
Solid dispersion system of water-insoluble furosemide in polyvinylpirolidon (PVP) was prepared by a solvent method in various ratios of 1 : 1, 1 : 3, I : 5, 1 : 7 and 1 : 9 of the drug and PVP, respectively in order to improve furosemide solubility and dissolution. The improvement of furosemide solubility was studied by a solubility method in a shaking waterbath. The solubility test showed that various concentrations of PVP and temperature gave statistically significant increased of furosemida solubility (P < 0,05).
The dissolution study of furosemide solid dispersion system was done using a dissolution tester at the rotation rate of 50 rpm. Furosemide concentration released was determined spectrophotometrically using a UV spectrofometer. This test showed a significant increased of furosemida solubility (P < 0,05), but with a prolonged of releasing time.
Key Word : solid dispersion, solubility, dissolution, bioavailability
Fairness Of Strategic Resource Allocation, Team Commitment And Commitment To Implementing Strategy In Indonesian International Joint Ventures
This study seeks to investigate the relationship between fairness of strategic resources allocation, management team’s commitment to multiple parties, and strategy of international joint ventures (IJVs) in Indonesia. Using a sample of 113 IJVs, the results of the regression analyses showed a positive relationship between fairness of strategic resources allocation and team’s commitment to implementing strategy whereby team commitment served as a mediator. In addition, fairness of strategic resources allocation was positively related to team commitment and team’s strategy. Im-plications, limitations, and suggestions for future research are discussed
Measuring Efficiency of Islamic Banks: Evidence From Indonesia
The present study investigates the efficiency of Islamic banks in Indonesia particularly for the period of 2014-2015. To meet that objective, the data envelopment analysis (DEA) particularly input-oriented, variable return to scale (VRS) has been employed. Additionally, twelve full-fledge Islamic commercial banks are included as the sample of the study. Having analysed using the DEA model, we find the average technical efficiency score of Islamic banks in 2014 is 0.843. In this regard, the inefficiency of Islamic banks is attributed equally to pure technical efficiency and scale efficiency. Moreover, the average technical efficiency score of Islamic banks for the year of 2015 is 0.832 which is lower than the previous year. The inefficiency of Islamic banks in 2015 is mainly contributed by the scale inefficiency. Moreover, the results reveal a declining productivity of Islamic banks during the period of study
Ketersediaan hayati relatif furosemida dalam bentuk dispersi padat =Comparative Bio availability Furosemide in Solid Dispersion Forms
ABSTRACT
Solid dispersion system of water-insoluble furosemide in polyvinylpirolidon (PVP) was prepared by a solvent method in various ratios of 1 : 5 and 1 : 7 of the drug and PVP, respectively in order to improve furosemide bioavailability.
The bioavailability of furosemide - PVP solid dispersion was compared with pure furosemide (control) and Lasix® (reference). The study was done in a cross over design with a single-dose peroral that administered to the white male rabbits (n = 6). Furosemide blood levels were determined spectrofluorometrically by an extraction method. The area under the blood concentration-time curve AUC0 y peak blood concentration Cmax and time to reach peak blood concentration Tmax were used to compare their bioavailabilities. The solid dispersion systems produced a higher extent of bioavailability than pure furosemide (P 0,05). Finally, furosemide - PVP solid dispersion (1: 7) was the best formulation with the highest extent of bioavailability and bioequivalence with the Lasix® formula\u27s.
Keywords: solid dispersion - solubility - dissolution - bioavailability -furosemide
ANALYSIS OF SOCIAL RESPONSIBILITY IMPLEMENTATION OF PT SEMEN PADANG BASED ON THE LEVEL OF COMMUNITY SATISFACTION WITH THE CORPORATE IMAGE IN PADANG CITY
The beginning of the formation of social responsibility or better known as Corporate Social Responsibility (CSR) is the provision of assistance to local organizations and lower-class communities in developing countries from companies operating in the vicinity. This study is intended to analyze the relationship between CSR Implementation on Community Satisfaction and Corporate Image. This research will use quantitative methods. Based on the research objectives, it was made to analyze the Implementation of PT Semen Padang's Social Responsibility based on the Level of Public Satisfaction with the Company's Image in the City of Padang. The number of samples in this study were 130 samples. The results of this study are the implementation of CSR has an effect on the level of community satisfaction. The implementation of CSR has an effect on corporate image, the level of community satisfaction has an effect on corporate image. The implementation of CSR affects the Company's Image through Community Satisfaction