For the Sake of the Image

Panel Talk on sound and imagel: Nina Danino and Larry Syder, chaired by Gareth Evans, Exhibition Events, For the Sake of the Image, curated by Suki Chan

Two-Dimensional Local-Global Class Field Theory in Positive Characteristic

Using the higher tame symbol and Kawada and Satake's Witt vector method, A. N. Parshin developed class field theory for higher local fields, defining reciprocity maps separately for the tamely ramified and wildly ramified cases. We extend this technique to the case of local-global fields associated to points and curves on an algebraic surface over a finite field.Comment: 57 page

New Wineskins: With What Materials? A Theology of New Wineskins for the 21st Century

Dr. Howard Snyder’s article on “New Wineskins: With What Materials?” focuses on developing “A Theology of New Wineskins for the 21st Century.” In his thoughtful article, he demonstrates his skill at historical reflection as he points to helpful and unhelpful places to develop our ecclesiology

New Wineskins: With What Materials? A Theology of New Wineskins for the 21st Century

Dr. Howard Snyder’s article on “New Wineskins: With What Materials?” focuses on developing “A Theology of New Wineskins for the 21st Century.” In his thoughtful article, he demonstrates his skill at historical reflection as he points to helpful and unhelpful places to develop our ecclesiology

A Generic Model Of Predicting Probability Of Success-Distress Of An Organization: A Logistic Regression Analysis

Many bankruptcy prediction models have been created over the years using a mix of variables derived mostly from accrual-based accounting statements and were industry specific. The primary issue with using a model comprised of accrual-based variables is that firm management can manipulate different components and make the balance sheet and income statement misleading (Wanuga 2006). Thus, firms appear financially healthy yet unable to meet the day-to-day cash flow needs of the firm; these financial issues are less likely to be hidden in the cash flow statement (Sharma 2001). In this study, we use a binary regression model with theoretically supported variables obtained from the cash flow statement to forecast firm success versus distress. Of particular interest, we examine firms representing 85 industries using firm data during and immediately following the greatest recession in United States history (Fieldhouse 2014; Lee 2014). The model is generic in the sense that it can be used to predict the probability of success-distress of any entity using the three major financial statements. We find that the overall model correctly classifies organizations 90.290 percent of the time

Two-dimensional local-global class field theory in positive characteristic

Using the higher tame symbol and Kawada and Satake’s Witt vector method, A.N. Parshin developed class field theory for positive characteristic higher local fields, defining reciprocity maps separately for the tamely ramified and wildly ramified cases. We prove reciprocity laws for these symbols using techniques of Morrow for the Witt symbol and Romo for the higher tame symbol. We then extend this method of defining a reciprocity map to the case of positive characteristic local- global fields associated to points and curves on an algebraic surface over a finite field

Dead-time compensators: performance and robustness issues

This paper will compare a number of PID and predictive controller strategies to compensate processes modelled in first order lag plus time delay (FOLPD) form. The performance and robustness of the resulting compensated systems are evaluated analytically (where appropriate) and in simulation

Two-dimensional local-global class field theory in positive characteristic

Using the higher tame symbol and Kawada and Satake’s Witt vector method, A.N. Parshin developed class field theory for positive characteristic higher local fields, defining reciprocity maps separately for the tamely ramified and wildly ramified cases. We prove reciprocity laws for these symbols using techniques of Morrow for the Witt symbol and Romo for the higher tame symbol. We then extend this method of defining a reciprocity map to the case of positive characteristic local- global fields associated to points and curves on an algebraic surface over a finite field

Targeting HCV Entry For Development of Therapeutics

Recent progress in defining the molecular mechanisms of Hepatitis C Virus (HCV) entry affords the opportunity to exploit new viral and host targets for therapeutic intervention. Entry inhibitors would limit the expansion of the infected cell reservoir, and would complement the many replication inhibitors now under development. The current model for the pathway of entry involves the initial docking of the virus onto the cell surface through interactions of virion envelope and associated low density lipoproteins (LDL) with cell surface glycosaminoglycans and lipoprotein receptors, followed by more specific utilization with other hepatocyte membrane proteins: Scavenger Receptor Class B type 1 (SR-BI), CD81, Claudin 1 (CLDN1) and Occludin (OCLN). The use of blockers of these interactions, e.g. specific antibodies, suggests that inhibition of any one step in the entry pathway can inhibit infection. Despite this knowledge base, the tools for compound screening, HCV pseudoparticles (HCVpp) and cell culture virus (HCVcc), and the ability to adapt them to industrial use are only recently available and as a result drug discovery initiatives are in their infancy. Several therapies aiming at modulating the virus envelope to prevent host cell binding are in early clinical testing. The first test case for blocking a cellular co-receptor is an SR-BI modulator. ITX 5061, an orally active small molecule, targets SR-BI and has shown potent antiviral activity against HCVpp and HCVcc. ITX 5061 has exhibited good safety in previous clinical studies, and is being evaluated in the clinic in chronic HCV patients and patients undergoing liver transplantation. Entry inhibitors promise to be valuable players in the future development of curative therapy against HCV