18 research outputs found

    Development of beam position monitors for final focus systems at the International Linear Collider

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    EThOS - Electronic Theses Online ServiceGBUnited Kingdo

    Towards an Advanced Linear International Collider

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    This document provides detailed information on the status of Advanced and Novel Accelerators techniques and describes the steps that need to be envisaged for their implementation in future accelerators, in particular for high energy physics applications. It complements the overview prepared for the update of the European Strategy for particle physics, and provides a detailed description of the field. The scientific priorities of the community are described for each technique of acceleration able to achieve accelerating gradient in the GeV~range or above. ALEGRO working group leaders have coordinated the preparation of their working group contribution and contributed to editing the documents. The preparation of this document was coordinated by the Advanced LinEar collider study GROup, ALEGRO. The content was defined through discussions at the ALEGRO workshop in Oxford UK, March 2018, and an advanced draft was discussed during a one day meeting prior to the AAC workshop in Breckenridge, CO, USA, August 2018. This document was submitted as an addendum to the ALEGRO submission to the European Strategy for Particle Physics

    Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic : an international, multicenter, comparative cohort study

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    PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks
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