23 research outputs found

    A new hereditary colorectal cancer network in the Middle East and eastern mediterranean countries to improve care for high-risk families

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    Colorectal cancer (CRC) has a very high incidence in the western world. Data from registries in the Middle East showed that the incidence of CRC is relatively low in these countries. However, these data also showed that CRC incidence has increased substantially over the past three decades and that a high proportion of cases are diagnosed at an early age (<50 years). In view of these findings, more attention should be paid to prevention. Because of the often limited financial resources, focused screening of individuals with hereditary CRC, in particular those with Lynch syndrome, appears to be the most cost-effective strategy. During recent meetings of the Palestinian Society of Gastroenterology and the Mediterranean Task force for Cancer Control (MTCC) in Jericho, and the Patient�s Friends Society of Jerusalem in Hebron the issue of hereditary CRC in the Middle East was discussed and the idea was conceived to establish a network on hereditary colorectal cancer (HCCN-ME) with the goal of improving care for high-risk groups in the Middle East and (Eastern) Mediterranean Countries. © 2017, The Author(s)

    Erratum to: A new hereditary colorectal cancer network in the Middle East and eastern Mediterranean countries to improve care for high-risk families (Familial Cancer, (2018), 17, 2, (209-212), 10.1007/s10689-017-0018-6)

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    Unfortunately, the 10th author name in the author group was published incorrectly in the original publication as �Keivan Maijdzadeh� the correct name is: Keivan Majidzadeh.Author name has also been corrected in the original publication. © Springer Science+Business Media B.V. 2017

    A new hereditary colorectal cancer network in the Middle East and eastern mediterranean countries to improve care for high-risk families

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    Colorectal cancer (CRC) has a very high incidence in the western world. Data from registries in the Middle East showed that the incidence of CRC is relatively low in these countries. However, these data also showed that CRC incidence has increased substantially over the past three decades and that a high proportion of cases are diagnosed at an early age (<50 years). In view of these findings, more attention should be paid to prevention. Because of the often limited financial resources, focused screening of individuals with hereditary CRC, in particular those with Lynch syndrome, appears to be the most cost-effective strategy. During recent meetings of the Palestinian Society of Gastroenterology and the Mediterranean Task force for Cancer Control (MTCC) in Jericho, and the Patient�s Friends Society of Jerusalem in Hebron the issue of hereditary CRC in the Middle East was discussed and the idea was conceived to establish a network on hereditary colorectal cancer (HCCN-ME) with the goal of improving care for high-risk groups in the Middle East and (Eastern) Mediterranean Countries. © 2017, The Author(s)

    Safety out of control: dopamine and defence

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    Performance enhancement of self-cleaning hydrophobic nanocoated photovoltaic panels in a dusty environment

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    The efficiency of a photovoltaic (PV) panels drops significantly in dusty environments. The variation in temperature could have a substantial impact on PV panel cells, which could further lead to high deterioration and eventually permanent damage to the PV material in the presence of dust. To resolve this issue, in this work a novel hydrophobic silicon dioxide (SiO2)-based nanoparticle coating is proposed for the PV panel, to shrink the surface stress developed between the water and the coated facet. Two identical PV modules were installed to conduct comparable experimental tests simultaneously. The first module is coated by the SiO2 nanoparticles, and the second is uncoated and used as a reference. To maintain coherency, the experiments are done in the same environmental conditions, cleaning the PV modules at regular intervals. Results reveal that the accumulated energy generated during this period of study was comprehensively enhanced. Moreover, the self-cleaning property of the hydrophobic surface of the coated panel allowed water droplets to slide smoothly down the PV module surface, carrying dust particles. Useful recommendations are made at the end to enhance the performance of PV panels in dusty environments.Funding: Natural Sciences and Engineering Research Council of Canada (NSERC), Discovery Grant no. RGPIN-2021-02574, Innocent Kamwa, Laval University.Scopu

    Synthesis and Preliminary Biological Evaluation of New Heterocyclic Carboxamide Models

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    The heterocyclic system is a promising core nucleus in many bioactive compounds. This work describes our effort to synthesize and characterize a set of new biphenyl, benzofuran and benzothiophene carboxamide derivatives. Our biological studies showed that compounds 10 and 17 have antifungal activity against C. galabrate more potent than fluconazole compounds 9, 10, and 17 exerted cytotoxic activities in immortalized embryonic mouse fibroblast cells (3T3) and a human cervical cancer cell line (HeLa); in particular, the cyclic amidine derivative 17 showed selective toxicity against HeLa. This study showed that the tested compounds have the potential to be useful as antitumor drugs after further optimization
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