Construcción de una institucionalidad democrática intercultural

Cobrar conciencia de la importancia de lo local como ineludible espacio de reconocimiento, de afirmación identitaria y de construcción colectiva de mecanismos de negociación con, o de resistencia a, ese entorno cada vez más absorbente en el que todo, incluidos los vertiginosos cambios tecnológicos, da la impresión de escapar a cualquier posibilidad de control, adquiriendo una autonomía que lleva la alienación del sujeto a límites insospechados no hace tanto tiempo. Semejante densificación de lo local, su centralidad en cualquier diseño colectivo de futuro que se pueda imaginar, es lo que algunos teóricos han denominado “glocalización”, como el reverso de la medalla de la globalización. (Párrafo extraído del texto a modo de resumen)Facultad de Bellas Arte

Construcción de una institucionalidad democrática intercultural

Cobrar conciencia de la importancia de lo local como ineludible espacio de reconocimiento, de afirmación identitaria y de construcción colectiva de mecanismos de negociación con, o de resistencia a, ese entorno cada vez más absorbente en el que todo, incluidos los vertiginosos cambios tecnológicos, da la impresión de escapar a cualquier posibilidad de control, adquiriendo una autonomía que lleva la alienación del sujeto a límites insospechados no hace tanto tiempo. Semejante densificación de lo local, su centralidad en cualquier diseño colectivo de futuro que se pueda imaginar, es lo que algunos teóricos han denominado “glocalización”, como el reverso de la medalla de la globalización. (Párrafo extraído del texto a modo de resumen)Facultad de Bellas Arte

Controlling structural and functional features of photosynthetic antenna

In order to gain control over the assembly and functioning of photosynthetic antenna, we have developed methods to manipulate pigment composition of bacterial LH1 complexes via their reconstitution with modified bacteriochlorophylls or carotenoids, major photoactive cofactors of these antennae. In the present work we show how the reconstitution and pigment exchange approach is applied to control structural and functional parameters of LH1 and its subunits. The size of the subunits and the energy of the first excited singlet state can be controlled via the use of detergent while the thermodynamics of LH1 formation can be modified using carotenoids and/or a co-solvent. Carotenoids affect the efficiency of the intracomplex energy transfer, while the replacement of native bacteriochlorophyll a with its Ni-substituted analog allows one to control the excited state properties of LH1. These results show that LH1 is a very promising model system applicable for the design of bio-inspired device performing solar energy conversion

An Integrated Approach towards Building a Simulation Model Supporting the Management of the Passenger Transportation System. Part 1 - Theoretical basis.

This article presents an integrated approach towards building a simulation model of the transportation network. The proposed method is based on the recommendations of the Blue Book for Sector of Public Transport in cities, agglomerations and regions issued by Jaspers (Joint Assistance to Support Projects in European Regions). It comprises six steps with such elements as econometric modelling, artificial neural networks and mathematical model. It is dedicated to developing simulation models for the purpose of picturing present situation and dependencies dominating in the transportation network, easily reflecting effects of potential modifications and providing forecasts for the future. The described hybrid method was verified in practice by building the simulation model which is presented in the next article in this series entitled: An Integrated Approach towards Building a Simulation Model Supporting the Management of the Passenger Transportation System. Part 2 – Case Study

Pulmonary metastases of the A549-derived lung adenocarcinoma tumors growing in nude mice : a multiple case study

Lung adenocarcinoma is a leading human malignancy with fatal prognosis. Ninety percent of the deaths, however, are caused by metastases. The model of subcutaneous tumor xenograft in nude mice was adopted to study the growth of control and photodynamically treated tumors derived from the human A549 lung adenocarcinoma cell line. As a side-result of the primary studies, observations on the metastasis of these tumors to the murine lungs were collected, and reported in the present paper. The metastasizing primary tumors were drained by a prominent number of lymphatic vessels. The metastatic tissue revealed the morphology of well-differentiated or trans-differentiated adenocarcinoma. Further histological and histochemical analyses demonstrated the presence of golden-brown granules in the metastatic tissue, similar to these found in the tumor tissue. In contrast to the primary tumors, the electron paramagnetic resonance spectroscopy revealed no nitric oxide - hemoglobin complexes (a source of intense paramagnetic signals), in the metastases. No metastases were found in other murine organs; however, white infarctions were identified in a single liver. Taken together, the A549-derived tumors growing subcutaneously in nude mice can metastasize and grow on site in the pulmonary tissue. Thus, they can represent an alternative for the model of induced metastatic nodule formation, following intravenous administration of the cancerous cells

A comparison of enzyme patterns in the granular and molecular layers of the rabbit cerebellar cortex

1. (1) Homogenates of hand-dissected granular and molecular layers of the cerebellar cortex of the rabbit were prepared and the following enzymes assayed: acetylcholinesterase, succinate-INT-reductase, particulate [alpha]-glycerophosphate dehydrogenase, arylsulfatase, glutamine synthetase and glutamic decarboxylase. Except for [alpha]-glycerophosphate dehydrogenase which was higher in the granular layer, all of the other activities showed higher values in the molecular layer.2. (2) Differential centrifugation of the homogenates into the nuclear, heavy particulate, microsomal and soluble fractions yielded peaks of relative specific activity of acetylcholinesterase in the microsomal, of glutamic decarboxylase in the soluble and the heavy particulate, of succinate-INT-reductase, [alpha]-glycerophosphate dehydrogenase and arylsulfatase in the heavy particulate and of glutamine synthetase in no single fraction.3. (3) Further separation of the heavy particulate fraction was accomplished by discontinuous gradient density centrifugation which yielded 5 fractions including a pellet. The distribution of glutamic decarboxylase and morphological evidence adduced previously20 make it possible to state that the system of excitatory synapses sedimented predominantly into fractions 0.8 M and 1.0 M of the molecular layer and fractions 1.2 M and 1.4 M of the granular layer. The distribution of [alpha]-glycerophosphate dehydrogenase, an enzyme predominantly associated with glial mitochondria29, further suggested an equal extent of contamination of the molecular and granular layers by glial cells.4. (4) This study also provides a finding of general interest, inasmuch as it reveals that, by prior physical separation of the granular and molecular layers followed by their differential and density gradient centrifugation, it is possible to achieve a partial separation, although by no means a purification, of their excitatory and inhibitory synaptic complexes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/34068/1/0000346.pd

Brooklyn Nets/Barclay Center

NY, Brookly